Gene Information gene info

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GENE：MYL9

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MYL9
FullNmae myosin light chain 9
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15754
EnsembleID ENSG00000101335
Uniprot P24844

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MYL9 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MYL9 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MYL9 GO:0001725,GO:0005509,GO:0005737,GO:0005829,GO:0005859,GO:0005938,GO:0006937,GO:0008307,GO:0030016,GO:0030018,GO:0030239,GO:0032036,GO:0070527

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MYL9 hsa:10398 path:hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human)
MYL9 hsa:10398 path:hsa04024 cAMP signaling pathway - Homo sapiens (human)
MYL9 hsa:10398 path:hsa04270 Vascular smooth muscle contraction - Homo sapiens (human)
MYL9 hsa:10398 path:hsa04360 Axon guidance - Homo sapiens (human)
MYL9 hsa:10398 path:hsa04510 Focal adhesion - Homo sapiens (human)
MYL9 hsa:10398 path:hsa04520 Adherens junction - Homo sapiens (human)
MYL9 hsa:10398 path:hsa04530 Tight junction - Homo sapiens (human)
MYL9 hsa:10398 path:hsa04670 Leukocyte transendothelial migration - Homo sapiens (human)
MYL9 hsa:10398 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
MYL9 hsa:10398 path:hsa04814 Motor proteins - Homo sapiens (human)
MYL9 hsa:10398 path:hsa04921 Oxytocin signaling pathway - Homo sapiens (human)
MYL9 hsa:10398 path:hsa05131 Shigellosis - Homo sapiens (human)
MYL9 hsa:10398 path:hsa05132 Salmonella infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SMARCA4 MYL9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MYL9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MYL9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MYL9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MYL9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MYL9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TIRAP MYL9 19724058 trascriptional regulation,stimulation inferred by curator TFlink
CD8A MYL9 19724058 trascriptional regulation,stimulation inferred by curator TFlink
MRTFA MYL9 19724058 trascriptional regulation,stimulation inferred by curator TFlink
MAL MYL9 19724058 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 MYL9 20876458 22898599 trascriptional regulation,stimulation inferred by curator TFlink
SRF MYL9 19724058 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004929F1 MYL9 24014830 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000AB32B MYL9 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002004E0 MYL9 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000058DCD8 MYL9 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000B7E30 MYL9 25416803 27121304 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CIT MYL9 22135298 phosphorylation N/A PhosphoSite
CDC42BPA MYL9 22135298 phosphorylation N/A PhosphoSite
ROCK1 MYL9 22135298 phosphorylation N/A PhosphoSite
PAK1 MYL9 22135298 phosphorylation N/A PhosphoSite
PRKCA MYL9 22135298 phosphorylation N/A PhosphoSite
MYLK MYL9 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
MCM2 MYL9 25348397 N/A physical interaction ComPPI
SP1 MYL9 25348397 N/A physical interaction ComPPI
PRKAA1 MYL9 17486097 24234451 25348397 phosphorylation reaction phosphorylation reaction,protein kinase assay ComPPI,IntAct
CFTR MYL9 25348397 N/A physical interaction ComPPI
TP73 MYL9 25348397 N/A physical interaction ComPPI
OCRL MYL9 24234451 25107275 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
EIF3I MYL9 25348397 N/A physical interaction ComPPI
HSPB1 MYL9 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
TP63 MYL9 25348397 N/A physical interaction ComPPI
PIP4K2B MYL9 25348397 N/A physical interaction ComPPI
EIF2S2 MYL9 25348397 N/A physical interaction ComPPI
CDC42BPA MYL9 11283256 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
FOXP1 MYL9 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TES MYL9 25348397 N/A physical interaction ComPPI
MYL12B MYL9 25348397 N/A physical interaction ComPPI
MYH9 MYL9 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CCND2 MYL9 25348397 N/A physical interaction ComPPI
PIP4K2C MYL9 25348397 N/A physical interaction ComPPI
MYL9 TP53 25348397 N/A physical interaction ComPPI
MYL9 FBXO25 25348397 N/A physical interaction ComPPI
MYL9 LRRK2 24234451 24510904 25348397 N/A protein array,physical interaction ComPPI,IntAct
MYL9 MYH14 25348397 N/A physical interaction ComPPI
MYL9 MYL12A 25348397 N/A physical interaction ComPPI
MYL9 FOXD3 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PRKCA MYL9 10514500 12802051 18835557 22136066 27898060 3036866 inhibition N/A OmniPath
EGFR MYL9 2526655 27898060 8578591 N/A N/A OmniPath
ROCK1 MYL9 27898060 8702756 stimulant N/A OmniPath
CDC42BPA MYL9 11283256 19851336 27898060 stimulant N/A OmniPath
PAK1 MYL9 10092231 10704379 11673466 12081505 12716456 15056655 15333633 15695393 17895359 18079119 18854160 21336303 25068972 26152729 26169356 27898060 3839510 N/A N/A OmniPath
PAK2 MYL9 10047984 27898060 N/A N/A OmniPath
DAPK3 MYL9 10356987 11384979 15096528 19851336 2526655 27898060 stimulant N/A OmniPath
MYLK MYL9 11942626 17287340 18669648 19851336 21457715 27898060 stimulant N/A OmniPath

Visualization










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