GENE:CNOT4
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CNOT4 |
| FullNmae | CCR4-NOT transcription complex subunit 4 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:7880 |
| EnsembleID | ENSG00000080802 |
| Uniprot | O95628 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CNOT4 | parthanatos | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| CNOT4 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| CNOT4 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CNOT4 | GO:0000289,GO:0003723,GO:0004842,GO:0004842,GO:0005515,GO:0005634,GO:0005829,GO:0006511,GO:0016567,GO:0030014,GO:0030014,GO:0045652,GO:0046872,GO:0051865 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| CNOT4 | hsa:4850 | path:hsa03018 | RNA degradation - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | CNOT4 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | CNOT4 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | CNOT4 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | CNOT4 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | CNOT4 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | CNOT4 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | CNOT4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | CNOT4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CNOT4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | CNOT4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | CNOT4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | CNOT4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | CNOT4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | CNOT4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | CNOT4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | CNOT4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | CNOT4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000122ED0 | CNOT4 | 17942906 25416803 | mrna cleavage,inhibition | quantitative reverse transcription pcr | TarBase |
| URS00002C0FCB | CNOT4 | 20371350 21572407 23592263 25416803 | mrna cleavage,inhibition | nucleotide sequence identification,clip | TarBase |
| URS000021D7C8 | CNOT4 | 20371350 23622248 25416803 | mrna cleavage,inhibition | nucleotide sequence identification,clash | TarBase |
| URS00000DDD35 | CNOT4 | 20371350 21572407 23592263 25416803 | mrna cleavage,inhibition | nucleotide sequence identification,clip | TarBase |
| URS000003ABC4 | CNOT4 | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
| URS000039607D | CNOT4 | 24374217 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001270D3 | CNOT4 | 20371350 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000CBE63 | CNOT4 | 20371350 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00003758F0 | CNOT4 | 20371350 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001F5B39 | CNOT4 | 20371350 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C7B2B | CNOT4 | 20371350 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000EED18 | CNOT4 | 20371350 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000000C73C | CNOT4 | 20371350 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000521626 | CNOT4 | 20371350 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00003BBF48 | CNOT4 | 20371350 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A7F58 | CNOT4 | 20371350 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B989F | CNOT4 | 20371350 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00002FC5B0 | CNOT4 | 20371350 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C85B2 | CNOT4 | 20371350 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00002198F3 | CNOT4 | 20371350 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000027352D | CNOT4 | 20371350 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000366551 | CNOT4 | 20371350 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000041FA2C | CNOT4 | 20371350 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F2EB0 | CNOT4 | 20371350 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000195F5B | CNOT4 | 20371350 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006FDD4 | CNOT4 | 20371350 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002ECEE4 | CNOT4 | 20371350 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000043D2C1 | CNOT4 | 20371350 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004BC299 | CNOT4 | 20371350 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000045DBD | CNOT4 | 20371350 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000031602A | CNOT4 | 20371350 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000251D0B | CNOT4 | 20371350 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C11BC | CNOT4 | 20371350 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000315338 | CNOT4 | 20371350 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000037D7E5 | CNOT4 | 20371350 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003883FE | CNOT4 | 20371350 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000298BA3 | CNOT4 | 20371350 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B3783 | CNOT4 | 20371350 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000042E1F | CNOT4 | 20371350 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002075FA | CNOT4 | 20371350 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000600E6 | CNOT4 | 20371350 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000039E1E1 | CNOT4 | 20371350 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000012930C | CNOT4 | 20371350 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| UBE2D1 | CNOT4 | 25348397 | N/A | physical interaction | ComPPI |
| MCM2 | CNOT4 | 25348397 | N/A | physical interaction | ComPPI |
| UBE2E3 | CNOT4 | 14525934 15001359 19690564 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid | ComPPI,HPRD,IntAct |
| UBE2D4 | CNOT4 | 19690564 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| EP300 | CNOT4 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| UBE2D2 | CNOT4 | 14525934 15001359 19690564 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid | ComPPI,HPRD,IntAct |
| UBE2N | CNOT4 | 19690564 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| MYC | CNOT4 | 21150319 24234451 25348397 | association | tandem affinity purification | ComPPI,IntAct |
| XPO1 | CNOT4 | 25348397 | N/A | physical interaction | ComPPI |
| UBE2D3 | CNOT4 | 19690564 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| ELAVL1 | CNOT4 | 25348397 | N/A | physical interaction | ComPPI |
| UBE2E1 | CNOT4 | 14525934 15001359 25348397 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD |
| CNOT8 | CNOT4 | 10637334 14525934 25348397 | N/A | two hybrid,two hybrid | ComPPI,HPRD |
| CNOT1 | CNOT4 | 10637334 14525934 25348397 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD |
| CNOT4 | UBE2W | 19690564 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| CNOT4 | RBM15 | 25348397 | N/A | physical interaction | ComPPI |
