Gene Information gene info

GENE:GLRX

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GLRX
FullNmae glutaredoxin
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4330
EnsembleID ENSG00000173221
Uniprot P35754

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GLRX pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GLRX autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GLRX GO:0005515,GO:0005634,GO:0005829,GO:0015038,GO:0015038,GO:0015949,GO:0045838,GO:0070062,GO:0080058,GO:2000651

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR GLRX 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 GLRX 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 GLRX 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 GLRX 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A GLRX 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXP3 GLRX 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 GLRX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA GLRX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GLRX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 GLRX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GLRX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GLRX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF GLRX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 GLRX 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000065D58 GLRX 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000003ABC4 GLRX 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00002ED720 GLRX 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F GLRX 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005F9738 GLRX 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000148B91 GLRX 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000036B845 GLRX 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000BD1DE GLRX 23446348 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TXN2 GLRX 25361965 interaction type N/A PTMCode2
GLRX TXN2 25361965 interaction type N/A PTMCode2
GLRX PRDX6 25361965 interaction type N/A PTMCode2
PRDX6 GLRX 25361965 interaction type N/A PTMCode2
GLRX MAP3K5 25361965 interaction type N/A PTMCode2
MAP3K5 GLRX 25361965 interaction type N/A PTMCode2
GLRX PTPN1 25361965 interaction type N/A PTMCode2
PTPN1 GLRX 25361965 interaction type N/A PTMCode2
GLRX TXN 25361965 interaction type N/A PTMCode2
TXN GLRX 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MAD2L2 GLRX 24234451 25348397 29656893 association anti tag coimmunoprecipitation ComPPI,IntAct
AQP5 GLRX 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MCM2 GLRX 25348397 N/A physical interaction ComPPI
DDIT4L GLRX 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CASP3 GLRX 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NIT1 GLRX 25348397 N/A physical interaction ComPPI
PTPN1 GLRX 10350489 14525934 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
MAP3K5 GLRX 12244106 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
GLRX NFIC 14525934 25348397 27898060 7961993 9417094 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
GLRX ATP7A 25348397 N/A physical interaction ComPPI
GLRX ATP7B 25348397 N/A physical interaction ComPPI
GLRX GOT2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GLRX MMP23B 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
GLRX CFAP298 25348397 N/A physical interaction ComPPI
GLRX ASNS 25348397 N/A physical interaction ComPPI
GLRX KYNU 25348397 N/A physical interaction ComPPI
GLRX MDH1 25348397 N/A physical interaction ComPPI
GLRX MTAP 25348397 N/A physical interaction ComPPI
GLRX SCCPDH 25348397 N/A physical interaction ComPPI
GLRX SOD1 25348397 N/A physical interaction ComPPI
GLRX TKT 25348397 N/A physical interaction ComPPI
GLRX TKTL2 25348397 N/A physical interaction ComPPI
GLRX TPR 25348397 N/A physical interaction ComPPI
GLRX TRAP1 25348397 N/A physical interaction ComPPI
GLRX TRIM25 25348397 N/A physical interaction ComPPI
GLRX TRIM62 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GLRX NFYA 19737086 27898060 stimulant N/A OmniPath
GLRX GAPDH 12556467 27898060 inhibition N/A OmniPath
GLRX MAP3K5 12244106 27898060 inhibition N/A OmniPath
GLRX IRF3 18309294 27898060 stimulant N/A OmniPath
GLRX ACTA1 12556467 27898060 stimulant N/A OmniPath
GLRX IKBKB 16916935 27898060 stimulant N/A OmniPath

Visualization