GeneInfo:
| GeneAttribute |
GeneDescription |
| GeneSymbol |
GLRX |
| FullNmae |
glutaredoxin |
| LocusType |
gene with protein product |
| Status |
Approved |
| HGNC_id |
HGNC:4330 |
| EnsembleID |
ENSG00000173221 |
| Uniprot |
P35754 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
| GLRX |
pyroptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
| GLRX |
autosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
| GeneSymbol |
Go id |
| GLRX |
GO:0005515,GO:0005634,GO:0005829,GO:0015038,GO:0015038,GO:0015949,GO:0045838,GO:0070062,GO:0080058,GO:2000651 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| AR |
GLRX |
20610535
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
| ETS1 |
GLRX |
20019798
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
| GATA1 |
GLRX |
19941826
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
| GATA2 |
GLRX |
19941826
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
| HIF1A |
GLRX |
19828020
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
| FOXP3 |
GLRX |
20554955
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
| SMARCA4 |
GLRX |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CEBPA |
GLRX |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CTCF |
GLRX |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| E2F1 |
GLRX |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOXA1 |
GLRX |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| HNF4A |
GLRX |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| MITF |
GLRX |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| SPI1 |
GLRX |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| URS0000065D58 |
GLRX |
18668040
25416803
|
mrna cleavage,inhibition |
experimental interaction detection |
TarBase |
| URS000003ABC4 |
GLRX |
19088304
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
| URS00002ED720 |
GLRX |
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00000B989F |
GLRX |
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00005F9738 |
GLRX |
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS0000148B91 |
GLRX |
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS000036B845 |
GLRX |
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00000BD1DE |
GLRX |
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| TXN2 |
GLRX |
25361965
|
interaction type |
N/A |
PTMCode2 |
| GLRX |
TXN2 |
25361965
|
interaction type |
N/A |
PTMCode2 |
| GLRX |
PRDX6 |
25361965
|
interaction type |
N/A |
PTMCode2 |
| PRDX6 |
GLRX |
25361965
|
interaction type |
N/A |
PTMCode2 |
| GLRX |
MAP3K5 |
25361965
|
interaction type |
N/A |
PTMCode2 |
| MAP3K5 |
GLRX |
25361965
|
interaction type |
N/A |
PTMCode2 |
| GLRX |
PTPN1 |
25361965
|
interaction type |
N/A |
PTMCode2 |
| PTPN1 |
GLRX |
25361965
|
interaction type |
N/A |
PTMCode2 |
| GLRX |
TXN |
25361965
|
interaction type |
N/A |
PTMCode2 |
| TXN |
GLRX |
25361965
|
interaction type |
N/A |
PTMCode2 |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| MAD2L2 |
GLRX |
24234451
25348397
29656893
|
association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
| AQP5 |
GLRX |
21988832
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
| MCM2 |
GLRX |
25348397
|
N/A |
physical interaction |
ComPPI |
| DDIT4L |
GLRX |
24234451
25348397
|
physical association |
two hybrid,two hybrid array,two hybrid prey pooling approach |
ComPPI,IntAct |
| CASP3 |
GLRX |
21988832
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
| NIT1 |
GLRX |
25348397
|
N/A |
physical interaction |
ComPPI |
| PTPN1 |
GLRX |
10350489
14525934
25348397
27898060
|
N/A |
experimental interaction detection,in vitro,in vivo |
ComPPI,HPRD,OmniPath |
| MAP3K5 |
GLRX |
12244106
14525934
25348397
|
N/A |
experimental interaction detection,physical interaction,in vitro |
ComPPI,HPRD |
| GLRX |
NFIC |
14525934
25348397
27898060
7961993
9417094
|
N/A |
experimental interaction detection,in vitro,in vivo |
ComPPI,HPRD,OmniPath |
| GLRX |
ATP7A |
25348397
|
N/A |
physical interaction |
ComPPI |
| GLRX |
ATP7B |
25348397
|
N/A |
physical interaction |
ComPPI |
| GLRX |
GOT2 |
21900206
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
| GLRX |
MMP23B |
21988832
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
| GLRX |
CFAP298 |
25348397
|
N/A |
physical interaction |
ComPPI |
| GLRX |
ASNS |
25348397
|
N/A |
physical interaction |
ComPPI |
| GLRX |
KYNU |
25348397
|
N/A |
physical interaction |
ComPPI |
| GLRX |
MDH1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| GLRX |
MTAP |
25348397
|
N/A |
physical interaction |
ComPPI |
| GLRX |
SCCPDH |
25348397
|
N/A |
physical interaction |
ComPPI |
| GLRX |
SOD1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| GLRX |
TKT |
25348397
|
N/A |
physical interaction |
ComPPI |
| GLRX |
TKTL2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| GLRX |
TPR |
25348397
|
N/A |
physical interaction |
ComPPI |
| GLRX |
TRAP1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| GLRX |
TRIM25 |
25348397
|
N/A |
physical interaction |
ComPPI |
| GLRX |
TRIM62 |
24234451
25348397
|
physical association |
two hybrid,two hybrid array,two hybrid prey pooling approach |
ComPPI,IntAct |
| GLRX |
NFYA |
19737086
27898060
|
stimulant |
N/A |
OmniPath |
| GLRX |
GAPDH |
12556467
27898060
|
inhibition |
N/A |
OmniPath |
| GLRX |
MAP3K5 |
12244106
27898060
|
inhibition |
N/A |
OmniPath |
| GLRX |
IRF3 |
18309294
27898060
|
stimulant |
N/A |
OmniPath |
| GLRX |
ACTA1 |
12556467
27898060
|
stimulant |
N/A |
OmniPath |
| GLRX |
IKBKB |
16916935
27898060
|
stimulant |
N/A |
OmniPath |
Visualization