Gene Information gene info

GENE:WDR77

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol WDR77
FullNmae WD repeat domain 77
LocusType gene with protein product
Status Approved
HGNC_id HGNC:29652
EnsembleID ENSG00000116455
Uniprot Q9BQA1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
WDR77 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
WDR77 GO:0000387,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005737,GO:0005794,GO:0005829,GO:0005829,GO:0006357,GO:0006511,GO:0007309,GO:0008284,GO:0008327,GO:0030374,GO:0031465,GO:0034709,GO:0034709,GO:0045893,GO:0048026,GO:0060528,GO:0060767,GO:0060770,GO:1990756

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PRR5 WDR77 17461779 23180781 physical association anti tag coimmunoprecipitation InnateDB
MYSM1 WDR77 17707232 23180781 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 WDR77 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 WDR77 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 WDR77 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CTCF WDR77 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 WDR77 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001B341F WDR77 21558443 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00001B341F WDR77 21558443 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00000DDD35 WDR77 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD WDR77 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002367FA WDR77 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EED18 WDR77 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004DA9DB WDR77 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A WDR77 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 WDR77 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 WDR77 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B WDR77 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 WDR77 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 WDR77 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000078918 WDR77 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000259AE4 WDR77 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000331800 WDR77 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002B0920 WDR77 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000003FD55 WDR77 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00004AC389 WDR77 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000016D2D4 WDR77 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK4 WDR77 22135298 phosphorylation N/A PhosphoSite
SNRPD3 WDR77 25361965 interaction type N/A PTMCode2
WDR77 SNRPD3 25361965 interaction type N/A PTMCode2
WDR77 CTDP1 25361965 interaction type N/A PTMCode2
CTDP1 WDR77 25361965 interaction type N/A PTMCode2
WDR77 SUZ12 25361965 interaction type N/A PTMCode2
SUZ12 WDR77 25361965 interaction type N/A PTMCode2
WDR77 SNRPD2 25361965 interaction type N/A PTMCode2
SNRPD2 WDR77 25361965 interaction type N/A PTMCode2
WDR77 SNRPE 25361965 interaction type N/A PTMCode2
SNRPE WDR77 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SNRPC WDR77 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SNRPB WDR77 11756452 14525934 25348397 N/A experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD
GPKOW WDR77 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SAP30BP WDR77 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPIL1 WDR77 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SMYD1 WDR77 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CCND1 WDR77 20951943 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SNRPF WDR77 11756452 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
UBL4A WDR77 25348397 N/A physical interaction ComPPI
CLNS1A WDR77 11756452 18984161 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
LSM3 WDR77 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LSM6 WDR77 25348397 N/A physical interaction ComPPI
SNRPD1 WDR77 11756452 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
GABARAPL2 WDR77 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SF3B4 WDR77 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KHDRBS2 WDR77 25348397 N/A physical interaction ComPPI
EMC2 WDR77 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SMAD1 WDR77 25348397 N/A physical interaction ComPPI
PPP1R8 WDR77 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GRB2 WDR77 21706016 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AR WDR77 25348397 N/A physical interaction ComPPI
PRKG1 WDR77 25348397 N/A physical interaction ComPPI
CUL3 WDR77 25348397 N/A physical interaction ComPPI
YWHAB WDR77 14525934 15324660 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
YWHAZ WDR77 15324660 24234451 25348397 physical association coimmunoprecipitation ComPPI,IntAct
HGS WDR77 25348397 N/A physical interaction ComPPI
UBC WDR77 25348397 N/A physical interaction ComPPI
NTRK1 WDR77 25348397 N/A physical interaction ComPPI
SMARCA4 WDR77 20951943 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MYC WDR77 17314511 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PRMT5 WDR77 11756452 12972618 14525934 18404153 20951943 21316606 22169276 22365833 22863883 23071334 23892143 24234451 25348397 26344197 26763441 26912361 27898060 methylation reaction,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,cosedimentation in solution,experimental interaction detection,molecular sieving,pull down,x-ray crystallography,physical interaction,in vitro,in vivo,methyltransferase assay ComPPI,HPRD,IntAct,OmniPath
YWHAQ WDR77 14525934 15324660 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,in vivo ComPPI,HPRD,IntAct
THOC1 WDR77 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ARRB1 WDR77 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ABCE1 WDR77 25348397 N/A physical interaction ComPPI
CTDP1 WDR77 12560496 14525934 15670829 24234451 25348397 physical association affinity chromatography technology,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
CUL2 WDR77 25348397 N/A physical interaction ComPPI
ARRB2 WDR77 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SNRPD3 WDR77 11756452 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
LSM11 WDR77 25348397 N/A physical interaction ComPPI
WDR77 SNRPD2 11756452 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
WDR77 SNRPE 11756452 14525934 24234451 25348397 N/A experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
WDR77 CXXC1 25348397 N/A physical interaction ComPPI
WDR77 SUZ12 16712789 22169276 25348397 27898060 N/A physical interaction ComPPI,OmniPath
WDR77 H2AC21 25348397 N/A physical interaction ComPPI
WDR77 MACROH2A1 25348397 N/A physical interaction ComPPI
WDR77 MBD2 25348397 N/A physical interaction ComPPI
WDR77 MYSM1 25348397 N/A physical interaction ComPPI
WDR77 CTNNBL1 25348397 N/A physical interaction ComPPI
WDR77 CDK4 20951943 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
WDR77 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WDR77 AGO4 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WDR77 USP12 25348397 N/A physical interaction ComPPI
WDR77 USP46 25348397 N/A physical interaction ComPPI
WDR77 TLE4 25348397 N/A physical interaction ComPPI
WDR77 UBE2Q2 25348397 N/A physical interaction ComPPI
WDR77 APEX1 25348397 N/A physical interaction ComPPI
WDR77 NKX3-1 25348397 N/A physical interaction ComPPI
WDR77 MAGOH 25348397 N/A physical interaction ComPPI
WDR77 SMURF1 25348397 N/A physical interaction ComPPI
WDR77 POLR2C 18562274 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WDR77 SF3A1 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
WDR77 SF1 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
WDR77 RBM5 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
WDR77 PQBP1 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
WDR77 AQR 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
WDR77 ZNF207 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
WDR77 HNRNPM 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
WDR77 PCBP2 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
WDR77 BAG2 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
WDR77 TOE1 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
WDR77 QKI 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
WDR77 PAN2 25348397 N/A physical interaction ComPPI
WDR77 FBXO6 25348397 N/A physical interaction ComPPI
WDR77 COPS4 25348397 N/A physical interaction ComPPI
WDR77 TBC1D4 25348397 N/A physical interaction ComPPI
WDR77 COPS7A 25348397 N/A physical interaction ComPPI
WDR77 COPS8 25348397 N/A physical interaction ComPPI
WDR77 DCAF8 25348397 N/A physical interaction ComPPI
WDR77 EPB41L2 25348397 N/A physical interaction ComPPI
WDR77 WWOX 25348397 N/A physical interaction ComPPI
WDR77 ASB15 25348397 N/A physical interaction ComPPI
WDR77 ZBTB1 25348397 N/A physical interaction ComPPI
WDR77 TP53 25348397 N/A physical interaction ComPPI
WDR77 CDK2 25348397 N/A physical interaction ComPPI
WDR77 RIOK1 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WDR77 PRKG2 25348397 N/A physical interaction ComPPI
WDR77 EPB41L3 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WDR77 NSD2 25348397 N/A physical interaction ComPPI
WDR77 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
WDR77 CDK2AP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WDR77 GAR1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WDR77 WIZ 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WDR77 CHTOP 25348397 N/A physical interaction ComPPI
WDR77 GAN 25348397 N/A physical interaction ComPPI
WDR77 CDK8 25348397 N/A physical interaction ComPPI
WDR77 CDK19 25348397 N/A physical interaction ComPPI
WDR77 CRY1 25348397 N/A physical interaction ComPPI
WDR77 TSC22D2 25348397 N/A physical interaction ComPPI
WDR77 CRBN 25348397 N/A physical interaction ComPPI
WDR77 CCT6B 25348397 N/A physical interaction ComPPI
WDR77 SNRPN 25348397 N/A physical interaction ComPPI
WDR77 CCT3 25348397 N/A physical interaction ComPPI
WDR77 CCT2 25348397 N/A physical interaction ComPPI
WDR77 CCT4 25348397 N/A physical interaction ComPPI
WDR77 CCT6A 25348397 N/A physical interaction ComPPI
WDR77 CCT5 25348397 N/A physical interaction ComPPI
WDR77 CIRBP 25348397 N/A physical interaction ComPPI
WDR77 CCT7 25348397 N/A physical interaction ComPPI
WDR77 NDUFAF8 25348397 N/A physical interaction ComPPI
WDR77 CYLD 25348397 N/A physical interaction ComPPI
WDR77 TRIM25 25348397 N/A physical interaction ComPPI
WDR77 SIRT7 25348397 N/A physical interaction ComPPI
WDR77 KMT2B 23995757 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WDR77 PRR5 25348397 N/A anti tag coimmunoprecipitation ComPPI
WDR77 ARHGAP8 25348397 N/A anti tag coimmunoprecipitation ComPPI
WDR77 AGO1 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
WDR77 AGO2 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
WDR77 UBE2F 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
WDR77 GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
WDR77 GABARAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
WDR77 HIF1AN 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
WDR77 IFT88 24234451 25348397 27173435 association anti tag coimmunoprecipitation ComPPI,IntAct
WDR77 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
TCP1 WDR77 25348397 N/A physical interaction ComPPI
H3C1 WDR77 25348397 N/A physical interaction ComPPI
EIF4A3 WDR77 25348397 N/A physical interaction ComPPI
IVL WDR77 24234451 26763441 physical association chromatin immunoprecipitation assay IntAct
METTL3 WDR77 24234451 29507755 association anti tag coimmunoprecipitation IntAct

Visualization