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GENE：HRH1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HRH1
FullNmae histamine receptor H1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5182
EnsembleID ENSG00000196639
Uniprot P35367

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HRH1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HRH1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HRH1 GO:0004930,GO:0004969,GO:0004993,GO:0005829,GO:0005886,GO:0005886,GO:0005886,GO:0006954,GO:0007186,GO:0007187,GO:0007200,GO:0007268,GO:0007613,GO:0008542,GO:0030425,GO:0030594,GO:0032962,GO:0043114,GO:0045202,GO:0045907,GO:0048167,GO:0071420,GO:0098664

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HRH1 hsa:3269 path:hsa04020 Calcium signaling pathway - Homo sapiens (human)
HRH1 hsa:3269 path:hsa04080 Neuroactive ligand-receptor interaction - Homo sapiens (human)
HRH1 hsa:3269 path:hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR HRH1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 HRH1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 HRH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HRH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 HRH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HRH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 HRH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS HRH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYB HRH1 24535227 trascriptional regulation,stimulation inferred by curator TFlink
NR3C1 HRH1 24535227 trascriptional regulation,stimulation inferred by curator TFlink
STAT5A HRH1 24535227 trascriptional regulation,stimulation inferred by curator TFlink
JUN HRH1 N/A trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A HRH1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000B59A2 HRH1 19074876 rna interference,inhibition array technology,experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00000B59A2 HRH1 19074876 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000075AB14 HRH1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000237AF9 HRH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000005481D HRH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000355E82 HRH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000254A6 HRH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 HRH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000076995 HRH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB HRH1 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CAMK2A HRH1 22135298 phosphorylation N/A PhosphoSite
PRKACA HRH1 22135298 phosphorylation N/A PhosphoSite
PRKG1 HRH1 22135298 phosphorylation N/A PhosphoSite
GRK2 HRH1 22135298 phosphorylation N/A PhosphoSite
PRKCA HRH1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
SH3GL3 HRH1 25348397 N/A pull down,physical interaction ComPPI
SH3GL2 HRH1 24234451 25348397 25517094 physical association pull down,physical interaction ComPPI,IntAct
SH3GL1 HRH1 25348397 N/A pull down,physical interaction ComPPI
IL6 HRH1 24234451 25241761 25348397 physical association physical interaction,proximity ligation assay ComPPI,IntAct
HRH1 YIPF3 24234451 28298427 physical association ubiquitin reconstruction IntAct
HRH1 SLC43A2 24234451 28298427 physical association ubiquitin reconstruction IntAct
HRH1 SLC35B1 24234451 28298427 physical association ubiquitin reconstruction IntAct
HRH1 ATP6V0A1 24234451 28298427 physical association ubiquitin reconstruction IntAct
HRH1 CNBP 24234451 28298427 physical association ubiquitin reconstruction IntAct
HRH1 ADGRA3 24234451 28298427 physical association ubiquitin reconstruction IntAct
HRH1 CD81 24234451 28298427 physical association ubiquitin reconstruction IntAct
HRH1 DHRS7 24234451 28298427 physical association ubiquitin reconstruction IntAct
HRH1 WLS 24234451 28298427 physical association ubiquitin reconstruction IntAct
HRH1 LIMS2 24234451 28298427 physical association ubiquitin reconstruction IntAct
HRH1 MAT2B 24234451 28298427 physical association ubiquitin reconstruction IntAct
PRKG1 HRH1 10101032 15107581 15328002 27898060 inhibition N/A OmniPath
PRKACA HRH1 15328002 27898060 inhibition N/A OmniPath
PRKCA HRH1 10101032 15107581 27898060 inhibition N/A OmniPath
CSNK2A1 HRH1 15107581 27898060 N/A N/A OmniPath
CAMK2A HRH1 10101032 15107581 27898060 inhibition N/A OmniPath
GRK2 HRH1 15107581 27898060 N/A N/A OmniPath
HDC HRH1 1768863 27898060 stimulant N/A OmniPath

Visualization










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