GENE：GRB10
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | GRB10 |
| FullNmae | growth factor receptor bound protein 10 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:4564 |
| EnsembleID | ENSG00000106070 |
| Uniprot | Q13322 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| GRB10 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| GRB10 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| GRB10 | GO:0005158,GO:0005158,GO:0005515,GO:0005737,GO:0005829,GO:0005886,GO:0008286,GO:0010467,GO:0030159,GO:0030178,GO:0030178,GO:0030949,GO:0032991,GO:0042326,GO:0046325,GO:0046627,GO:0046627,GO:0048009,GO:0070371,GO:0120162,GO:1904738 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| GRB10 | hsa:2887 | path:hsa04150 | mTOR signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GRB10 | RAF1 | 10585452 23180781 | physical association | anti tag coimmunoprecipitation,two hybrid | InnateDB |
| GRB10 | INSR | 12493740 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| GRB10 | AKT1 | 15722337 23180781 | phosphorylation reaction | in-gel kinase assay | InnateDB |
| APP | GRB10 | 21832049 23180781 | physical association | protein array | InnateDB |
| GRB10 | NEDD4 | 12697834 23331499 | stimulation | N/A | SignaLink,SignaLink |
| RET | GRB10 | 23331499 7665556 | stimulation | N/A | SignaLink |
| GRB10 | ABL1 | 23331499 9006901 9747873 | stimulation | N/A | SignaLink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GRB10 | JAK2 | 20005715 | interaction type | N/A | PSP |
| GRB10 | ABL1 | 20005715 | interaction type | N/A | PSP |
| GRB10 | RAF1 | 10585452 18988627 20005715 21071413 9553107 | interaction type | N/A | PSP,SignaLink |
| GRB10 | INSR | 12493740 18988627 20005715 21071413 7479769 8621530 9506989 | interaction type | N/A | PSP,SignaLink |
| GRB10 | FYN | 20005715 | interaction type | N/A | PSP |
| GRB10 | RET | 20005715 | interaction type | N/A | PSP |
| GRB10 | IGF1R | 20005715 | interaction type | N/A | PSP |
| GRB10 | PDGFRB | 20005715 | interaction type | N/A | PSP |
| GRB10 | BCR | 20005715 | interaction type | N/A | PSP |
| GRB10 | SRC | 20005715 | interaction type | N/A | PSP |
| GRB10 | MAPK1 | 20005715 | interaction type | N/A | PSP |
| GRB10 | AKT1 | 20005715 | interaction type | N/A | PSP |
| GRB10 | KDR | 20005715 | interaction type | N/A | PSP |
| GRB10 | NEDD4 | 20005715 | interaction type | N/A | PSP |
| GRB10 | MAP2K1 | 20005715 | interaction type | N/A | PSP |
| GRB10 | ABL1 | 20005715 | N/A | N/A | SignaLink |
| GRB10 | IGF1R | 12697834 18988627 19165858 20005715 21071413 8621530 8764099 8776723 9506989 | N/A | N/A | SignaLink |
| GRB10 | NEDD4 | 20005715 | N/A | N/A | SignaLink |
| GRB10 | SRC | 10871840 20005715 21071413 | N/A | N/A | SignaLink |
| GRB10 | AKT1 | 11809791 18988627 20005715 20005715 | N/A | N/A | SignaLink |
| GRB10 | BCR | 18988627 20005715 20005715 21071413 9747873 9747873 9747873 9747873 | N/A | N/A | SignaLink |
| GRB10 | FYN | 10871840 20005715 20005715 21071413 | N/A | N/A | SignaLink |
| GRB10 | JAK2 | 18988627 20005715 20005715 9632636 | N/A | N/A | SignaLink |
| GRB10 | KDR | 11494124 18988627 20005715 20005715 | N/A | N/A | SignaLink |
| GRB10 | MAP2K1 | 18988627 20005715 20005715 21071413 9553107 9553107 9553107 9553107 | N/A | N/A | SignaLink |
| GRB10 | MAPK1 | 20005715 20005715 | N/A | N/A | SignaLink |
| GRB10 | PDGFRB | 18988627 20005715 20005715 9006901 | N/A | N/A | SignaLink |
| GRB10 | RET | 18988627 20005715 20005715 21071413 7665556 7665556 | N/A | N/A | SignaLink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | GRB10 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | GRB10 | 18414489 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | GRB10 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | GRB10 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TP63 | GRB10 | 17521434 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | GRB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | GRB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | GRB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | GRB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | GRB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | GRB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | GRB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | GRB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HIF1A | GRB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | GRB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | GRB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PRDM14 | GRB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | GRB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | GRB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | GRB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | GRB10 | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00002C0FCB | GRB10 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | nucleotide sequence identification,clip | TarBase |
| URS0000070B1D | GRB10 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000153377 | GRB10 | 23622248 25416803 26236014 | mrna cleavage,inhibition | clash,miRNA interference luciferase reporter assay | TarBase |
| URS0000029EBD | GRB10 | 24608802 25416803 | mrna cleavage,inhibition | experimental interaction detection,western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr | TarBase |
| URS0000195F5B | GRB10 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005CC20C | GRB10 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002ECEE4 | GRB10 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000043D2C1 | GRB10 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004BC299 | GRB10 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000045DBD | GRB10 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D2F5 | GRB10 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006F90B | GRB10 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000012930C | GRB10 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C11BC | GRB10 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000031602A | GRB10 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000251D0B | GRB10 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000315338 | GRB10 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006FDD4 | GRB10 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000250A40 | GRB10 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000170CF4 | GRB10 | 25416803 26236014 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
| URS0000070CD2 | GRB10 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000346991 | GRB10 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000027080C | GRB10 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000041E949 | GRB10 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000508C13 | GRB10 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00003883FE | GRB10 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000037D7E5 | GRB10 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SRC | GRB10 | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
| MAPK1 | GRB10 | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
| MTOR | GRB10 | 22135298 | phosphorylation | N/A | PhosphoSite |
| FYN | GRB10 | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
| NEDD4 | GRB10 | 25361965 | interaction type | N/A | PTMCode2 |
| GRB10 | NEDD4 | 25361965 | interaction type | N/A | PTMCode2 |
| RAF1 | GRB10 | 25361965 | interaction type | N/A | PTMCode2 |
| GRB10 | RAF1 | 25361965 | interaction type | N/A | PTMCode2 |
| GRB10 | MAPK1 | 25361965 | interaction type | N/A | PTMCode2 |
| GHR | GRB10 | 25361965 | interaction type | N/A | PTMCode2 |
| GRB10 | GHR | 25361965 | interaction type | N/A | PTMCode2 |
| KDR | GRB10 | 25361965 | interaction type | N/A | PTMCode2 |
| GRB10 | KDR | 25361965 | interaction type | N/A | PTMCode2 |
| IGF1R | GRB10 | 25361965 | interaction type | N/A | PTMCode2 |
| GRB10 | IGF1R | 25361965 | interaction type | N/A | PTMCode2 |
| GRB10 | GIGYF2 | 25361965 | interaction type | N/A | PTMCode2 |
| GIGYF2 | GRB10 | 25361965 | interaction type | N/A | PTMCode2 |
| GRB10 | FYN | 25361965 | interaction type | N/A | PTMCode2 |
| GIGYF1 | GRB10 | 25361965 | interaction type | N/A | PTMCode2 |
| GRB10 | GIGYF1 | 25361965 | interaction type | N/A | PTMCode2 |
| GRB10 | SRC | 25361965 | interaction type | N/A | PTMCode2 |
| CSF1R | GRB10 | 25361965 | interaction type | N/A | PTMCode2 |
| GRB10 | CSF1R | 25361965 | interaction type | N/A | PTMCode2 |
| MAP2K1 | GRB10 | 25361965 | interaction type | N/A | PTMCode2 |
| GRB10 | MAP2K1 | 25361965 | interaction type | N/A | PTMCode2 |
| EGFR | GRB10 | 25361965 | interaction type | N/A | PTMCode2 |
| GRB10 | EGFR | 25361965 | interaction type | N/A | PTMCode2 |
| ABL1 | GRB10 | 25361965 | interaction type | N/A | PTMCode2 |
| GRB10 | ABL1 | 25361965 | interaction type | N/A | PTMCode2 |
| IRS1 | GRB10 | 25361965 | interaction type | N/A | PTMCode2 |
| GRB10 | IRS1 | 25361965 | interaction type | N/A | PTMCode2 |
| AKT1 | GRB10 | 25361965 | interaction type | N/A | PTMCode2 |
| GRB10 | AKT1 | 25361965 | interaction type | N/A | PTMCode2 |
| KIT | GRB10 | 25361965 | interaction type | N/A | PTMCode2 |
| GRB10 | KIT | 25361965 | interaction type | N/A | PTMCode2 |
| EPHB1 | GRB10 | 25361965 | interaction type | N/A | PTMCode2 |
| GRB10 | EPHB1 | 25361965 | interaction type | N/A | PTMCode2 |
| RET | GRB10 | 25361965 | interaction type | N/A | PTMCode2 |
| GRB10 | RET | 25361965 | interaction type | N/A | PTMCode2 |
| JAK2 | GRB10 | 25361965 | interaction type | N/A | PTMCode2 |
| GRB10 | JAK2 | 25361965 | interaction type | N/A | PTMCode2 |
| DOK1 | GRB10 | 25361965 | interaction type | N/A | PTMCode2 |
| GRB10 | DOK1 | 25361965 | interaction type | N/A | PTMCode2 |
| INSR | GRB10 | 25361965 | interaction type | N/A | PTMCode2 |
| GRB10 | INSR | 25361965 | interaction type | N/A | PTMCode2 |
| BCR | GRB10 | 25361965 | interaction type | N/A | PTMCode2 |
| GRB10 | BCR | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| MAPK1 | GRB10 | 14525934 15952796 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| KIT | GRB10 | 11809791 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| PIK3R1 | GRB10 | 23246379 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| SRC | GRB10 | 10871840 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| GRB10 | PDGFRB | 10454568 14525934 24234451 25348397 9006901 | association | experimental interaction detection,pull down,in vitro | ComPPI,HPRD,IntAct |
| GRB10 | MAP2K1 | 14525934 25348397 9553107 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| GRB10 | KDR | 11494124 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| GRB10 | ELK1 | 14525934 25348397 8798570 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| GRB10 | EPHB1 | 14525934 24234451 25348397 8798570 | association,physical association | two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,two hybrid | ComPPI,HPRD,IntAct |
| GRB10 | GHR | 14525934 25348397 9632636 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| GRB10 | NEDD4 | 10446181 12697834 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| GRB10 | GIGYF1 | 12771153 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD |
| GRB10 | GIGYF2 | 12771153 14525934 25348397 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD |
| GRB10 | MEGF10 | 12421765 14525934 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
| GRB10 | DOK1 | 11551902 14525934 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| GRB10 | EGFR | 14525934 24234451 24658140 25348397 9006901 9506989 | physical association | two hybrid,experimental interaction detection,pull down,ubiquitin reconstruction,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
| GRB10 | FYN | 10871840 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| GRB10 | INSR | 12493740 14525934 24234451 25348397 7479769 8621530 9506989 | physical association | anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,protein three hybrid,in vitro,in vivo,two hybrid | ComPPI,HPRD,IntAct |
| GRB10 | JAK2 | 14525934 25348397 9632636 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| GRB10 | BCR | 14525934 25348397 9747873 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| GRB10 | AKT1 | 11809791 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| GRB10 | RAF1 | 10585452 14525934 25348397 9553107 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| GRB10 | RET | 14525934 25348397 7665556 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| GRB10 | IRS1 | 25348397 | N/A | physical interaction | ComPPI |
| GRB10 | ABL1 | 25348397 | N/A | physical interaction | ComPPI |
| GRB10 | NOA1 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| GRB10 | ELAVL1 | 25348397 | N/A | physical interaction | ComPPI |
| GRB10 | IRS2 | 25348397 | N/A | physical interaction | ComPPI |
| GRB10 | APP | 25348397 | N/A | physical interaction | ComPPI |
| GRB10 | DENND5B | 25348397 | N/A | physical interaction | ComPPI |
| GRB10 | IQCB1 | 21565611 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| GRB10 | CNOT9 | 25348397 | N/A | physical interaction | ComPPI |
| GRB10 | HECW2 | 25348397 | N/A | physical interaction | ComPPI |
| GRB10 | YWHAE | 25348397 | N/A | physical interaction | ComPPI |
| GRB10 | ZDHHC17 | 24234451 24705354 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| GRB10 | CHFR | 25348397 | N/A | physical interaction | ComPPI |
| GRB10 | NARS1 | 25348397 | N/A | physical interaction | ComPPI |
| GRB10 | BAIAP2 | 25348397 | N/A | physical interaction | ComPPI |
| GRB10 | RCAN3 | 24234451 25348397 25814554 | physical association | two hybrid,physical interaction,two hybrid array,luminescence based mammalian interactome mapping,validated two hybrid | ComPPI,IntAct |
| GRB10 | XPO1 | 25348397 | N/A | physical interaction | ComPPI |
| GRB10 | WDR59 | 25348397 | N/A | physical interaction | ComPPI |
| GRB10 | IL2RG | 25348397 | N/A | physical interaction | ComPPI |
| GRB10 | IL4R | 25348397 | N/A | physical interaction | ComPPI |
| GRB10 | HNRNPL | 25348397 | N/A | physical interaction | ComPPI |
| GRB10 | NRAS | 25348397 | N/A | anti tag coimmunoprecipitation,physical interaction | ComPPI |
| GRB10 | CAV1 | 20808760 24234451 25348397 | N/A | protein array,physical interaction | ComPPI,IntAct |
| GRB10 | GRB2 | 17474147 24234451 25348397 | physical association | peptide array | ComPPI,IntAct |
| GRB10 | ABI1 | 20598684 24234451 25348397 | N/A | array technology | ComPPI,IntAct |
| GRB10 | FLT3 | 23246379 24234451 25348397 | physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down | ComPPI,IntAct |
| NEDD4L | GRB10 | 25348397 | N/A | physical interaction | ComPPI |
| MAP3K14 | GRB10 | 12853971 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| IGF1R | GRB10 | 14525934 24234451 25348397 8621530 8764099 9506989 | physical association | two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD,IntAct |
| MKI67 | GRB10 | 24234451 26949251 | association | anti tag coimmunoprecipitation | IntAct |
| SRC | GRB10 | 10871840 27898060 | inhibition,stimulant | N/A | OmniPath |
| FYN | GRB10 | 10871840 27898060 | inhibition,stimulant | N/A | OmniPath |
| RET | GRB10 | 27898060 7665556 8631863 | stimulant | N/A | OmniPath |
| IGF1R | GRB10 | 12697834 19165858 20980250 27898060 8621530 8764099 8776723 9062339 9506989 | stimulant | N/A | OmniPath |
| GRB10 | IGF1R | 12697834 19165858 20980250 21659604 27898060 8621530 8764099 8776723 9062339 9506989 | inhibition | N/A | OmniPath |
| AKT1 | GRB10 | 11809791 15722337 27898060 | N/A | N/A | OmniPath |
| GRB10 | NEDD4 | 10446181 12697834 20980250 27898060 | stimulant | N/A | OmniPath |
| MAPK3 | GRB10 | 15952796 18220336 18669648 27898060 | stimulant | N/A | OmniPath |
| GRB10 | PIK3CA | 12783867 27898060 | stimulant | N/A | OmniPath |
| GRB10 | ABL1 | 27898060 9006901 9747873 | stimulant | N/A | OmniPath |
| RAF1 | GRB10 | 10585452 27898060 9553107 | N/A | N/A | OmniPath |
| GRB10 | RAF1 | 10585452 27898060 9553107 | N/A | N/A | OmniPath |
| MAPK1 | GRB10 | 15952796 18220336 18669648 20068231 27898060 | stimulant | N/A | OmniPath |
| MTOR | GRB10 | 15952796 21659604 27898060 | stimulant | N/A | OmniPath |
| INSR | GRB10 | 10871840 12493740 12783867 15664450 27898060 7479769 8621530 9006901 9506989 | stimulant | N/A | OmniPath |
| GRB10 | INSR | 10871840 12493740 15664450 21659604 27898060 7479769 8621530 9006901 9506989 | inhibition | N/A | OmniPath |
| TEC | GRB10 | 27898060 9753425 | N/A | N/A | OmniPath |