GENE:ICAM3
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ICAM3 |
| FullNmae | intercellular adhesion molecule 3 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:5346 |
| EnsembleID | ENSG00000076662 |
| Uniprot | P32942 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ICAM3 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ICAM3 | GO:0005102,GO:0005178,GO:0005178,GO:0005515,GO:0005886,GO:0006909,GO:0007155,GO:0070062,GO:0098609 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| ICAM3 | hsa:3385 | path:hsa04514 | Cell adhesion molecules - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ESR1 | ICAM3 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | ICAM3 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | ICAM3 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| CEBPA | ICAM3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ICAM3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | ICAM3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | ICAM3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | ICAM3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | ICAM3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | ICAM3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | ICAM3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX3 | ICAM3 | 22479382 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| PRKCQ | ICAM3 | 22135298 | phosphorylation | N/A | PhosphoSite |
| ICAM3 | ITGB2 | 25361965 | interaction type | N/A | PTMCode2 |
| ITGB2 | ICAM3 | 25361965 | interaction type | N/A | PTMCode2 |
| ICAM3 | CD209 | 25361965 | interaction type | N/A | PTMCode2 |
| CD209 | ICAM3 | 25361965 | interaction type | N/A | PTMCode2 |
| ICAM3 | CLEC4M | 25361965 | interaction type | N/A | PTMCode2 |
| CLEC4M | ICAM3 | 25361965 | interaction type | N/A | PTMCode2 |
| ICAM3 | EZR | 25361965 | interaction type | N/A | PTMCode2 |
| EZR | ICAM3 | 25361965 | interaction type | N/A | PTMCode2 |
| ICAM3 | ITGAL | 25361965 | interaction type | N/A | PTMCode2 |
| ITGAL | ICAM3 | 25361965 | interaction type | N/A | PTMCode2 |
| ICAM3 | MSN | 25361965 | interaction type | N/A | PTMCode2 |
| MSN | ICAM3 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SEC22A | ICAM3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| SFTPC | ICAM3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| SMCO4 | ICAM3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| ACTB | ICAM3 | 25348397 | N/A | physical interaction | ComPPI |
| PRKCQ | ICAM3 | 14525934 25348397 9268366 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| ITGB2 | ICAM3 | 25348397 | N/A | in vitro,in vivo | ComPPI |
| ZBTB16 | ICAM3 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| MSN | ICAM3 | 10733515 11784723 14525934 23463506 25348397 27898060 9298994 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| CLDN4 | ICAM3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| EZR | ICAM3 | 11784723 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| ITGAL | ICAM3 | 11353828 14525934 15728350 24234451 25348397 | N/A | experimental interaction detection,x-ray crystallography,in vitro,in vivo | ComPPI,HPRD,IntAct |
| ICAM3 | ITGAD | 14525934 25348397 8777714 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD |
| ICAM3 | APP | 25348397 | N/A | physical interaction | ComPPI |
| ICAM3 | ZNF431 | 25348397 | N/A | physical interaction | ComPPI |
| ICAM3 | TMEM192 | 25348397 | N/A | physical interaction | ComPPI |
| ICAM3 | FUT8 | 25348397 | N/A | physical interaction | ComPPI |
| ICAM3 | NINJ2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| ICAM3 | TSPO | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| ICAM3 | SMIM1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CD209 | ICAM3 | 10721994 11017109 11799126 14525934 25348397 27898060 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| CLEC4M | ICAM3 | 11257134 25348397 27898060 | N/A | in vitro | ComPPI,OmniPath |
| EDDM3B | ICAM3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| PRKCQ | ICAM3 | 11784723 27898060 9268366 | stimulant | N/A | OmniPath |
| GRK2 | ICAM3 | 11784723 27898060 | N/A | N/A | OmniPath |
