Gene Information gene info

  1. Home

GENE：CNOT1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CNOT1
FullNmae CCR4-NOT transcription complex subunit 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7877
EnsembleID ENSG00000125107
Uniprot A5YKK6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CNOT1 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CNOT1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CNOT1 GO:0000122,GO:0000288,GO:0000289,GO:0000932,GO:0000932,GO:0000932,GO:0001829,GO:0003723,GO:0004535,GO:0005515,GO:0005615,GO:0005634,GO:0005829,GO:0005829,GO:0010606,GO:0016020,GO:0017148,GO:0019904,GO:0030014,GO:0030014,GO:0030015,GO:0030331,GO:0033147,GO:0035195,GO:0042974,GO:0048387,GO:0060090,GO:0060090,GO:0060213,GO:0060213,GO:0061014,GO:0070016,GO:1900153,GO:2000036

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CNOT1 hsa:23019 path:hsa03018 RNA degradation - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 CNOT1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 CNOT1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 CNOT1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CNOT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CNOT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CNOT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CNOT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CNOT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CNOT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CNOT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CNOT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR CNOT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EC1BE CNOT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000DDD35 CNOT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001012BC CNOT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000031602A CNOT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004505E4 CNOT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 CNOT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 CNOT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000BE495 CNOT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002C0FCB CNOT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000170CF4 CNOT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001CC864 CNOT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 CNOT1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
TOB1 CNOT1 25361965 interaction type N/A PTMCode2
CNOT1 TOB1 25361965 interaction type N/A PTMCode2
CNOT8 CNOT1 25361965 interaction type N/A PTMCode2
CNOT1 CNOT8 25361965 interaction type N/A PTMCode2
CNOT2 CNOT1 25361965 interaction type N/A PTMCode2
CNOT1 CNOT2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KRT18 CNOT1 25348397 N/A physical interaction ComPPI
DDX6 CNOT1 25348397 N/A physical interaction ComPPI
SNW1 CNOT1 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L CNOT1 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
NANOS2 CNOT1 25348397 N/A physical interaction ComPPI
GTF2A1 CNOT1 25348397 N/A physical interaction ComPPI
KEAP1 CNOT1 25348397 N/A physical interaction ComPPI
EGLN3 CNOT1 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
MMP7 CNOT1 25348397 N/A physical interaction ComPPI
TOB1 CNOT1 18377426 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 CNOT1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SND1 CNOT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GRB2 CNOT1 19380743 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
JUN CNOT1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
FHL2 CNOT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THRB CNOT1 14525934 16778766 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
GADD45B CNOT1 25348397 N/A physical interaction ComPPI
UBTF CNOT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NTRK1 CNOT1 25348397 N/A physical interaction ComPPI
BTRC CNOT1 25348397 N/A physical interaction ComPPI
BAG6 CNOT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CAPZA1 CNOT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HNRNPL CNOT1 25348397 N/A physical interaction ComPPI
ZFP36 CNOT1 23644599 25348397 27898060 N/A isothermal titration calorimetry,pull down,x-ray crystallography,physical interaction ComPPI,OmniPath
PPARG CNOT1 14525934 16778766 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
BTG2 CNOT1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SDCBP CNOT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XPO1 CNOT1 25348397 N/A physical interaction ComPPI
SSX2IP CNOT1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
RAVER1 CNOT1 25348397 N/A physical interaction ComPPI
CENPJ CNOT1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
VCAM1 CNOT1 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
HIF1AN CNOT1 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
ATRX CNOT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IBTK CNOT1 25348397 N/A physical interaction ComPPI
PEX14 CNOT1 21525035 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
TRIM25 CNOT1 25348397 N/A physical interaction ComPPI
BRCA1 CNOT1 25348397 N/A physical interaction ComPPI
CNOT7 CNOT1 21278420 22977175 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,molecular sieving,pull down,x-ray crystallography,physical interaction ComPPI,IntAct
CNOT8 CNOT1 10637334 14525934 16778766 17353931 22977175 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
TOB2 CNOT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AFF4 CNOT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EPAS1 CNOT1 25348397 N/A physical interaction ComPPI
AURKAIP1 CNOT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NANOS1 CNOT1 25348397 N/A physical interaction ComPPI
FBXW11 CNOT1 25348397 N/A physical interaction ComPPI
TNKS1BP1 CNOT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BTG3 CNOT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT1 CNOT2 10637334 12215531 14525934 16263706 16778766 19707589 20386698 21669201 24121231 24234451 25348397 26496610 27898060 7926748 9463387 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vivo,tandem affinity purification,inference by socio-affinity scoring,two hybrid ComPPI,HPRD,IntAct,OmniPath
CNOT1 CNOT4 10637334 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
CNOT1 CNOT3 14525934 16778766 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
CNOT1 USP22 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT1 SIRT7 25348397 N/A physical interaction ComPPI
CNOT1 CNOT9 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT1 ALB 15174051 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT1 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
CNOT1 CNOT6L 17452450 21984185 22977175 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT1 CNOT6 17452450 22977175 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CNOT1 PPP6R1 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CNOT1 CCAR2 25348397 N/A physical interaction ComPPI
CNOT1 POLR1C 25348397 N/A physical interaction ComPPI
CNOT1 LGR4 25348397 N/A physical interaction ComPPI
CNOT1 TNRC6A 21981923 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT1 TNRC6C 21981923 21984184 21984185 23463101 24234451 25348397 27898060 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct,OmniPath
CNOT1 RXRA 14525934 16778766 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD,IntAct
CNOT1 CCDC8 25348397 N/A physical interaction ComPPI
CNOT1 NANOS3 25348397 N/A physical interaction ComPPI
CNOT1 TRIM74 25348397 N/A physical interaction ComPPI
CNOT1 CT55 25348397 N/A physical interaction ComPPI
CNOT1 CAPZA2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT1 SCN2B 25348397 N/A physical interaction ComPPI
CNOT1 TNRC6B 21981923 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CNOT1 AGO2 21981923 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT1 IFI16 25348397 N/A physical interaction ComPPI
CNOT1 MED4 25348397 N/A physical interaction ComPPI
CNOT1 CEP152 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CNOT1 CNTROB 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CNOT1 NINL 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CNOT1 ABCF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT1 CAPZB 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
CNOT1 RPS27 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT1 NUP42 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT1 REEP5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT1 CNOT10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT1 PI4K2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT1 CNOT11 23232451 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,tandem affinity purification ComPPI,IntAct
CNOT1 GPBP1L1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT1 INTS5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT1 MEX3C 25348397 N/A physical interaction ComPPI
CNOT1 RC3H1 25348397 N/A physical interaction ComPPI
CNOT1 EYA2 25348397 N/A physical interaction ComPPI
CNOT1 RIBC1 25348397 N/A physical interaction ComPPI
CNOT1 IZUMO1 25348397 N/A physical interaction ComPPI
CNOT1 G3BP1 25348397 N/A physical interaction ComPPI
CNOT1 STK40 25348397 N/A physical interaction ComPPI
CNOT1 KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
OBI1 CNOT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TEX13A CNOT1 25348397 N/A physical interaction ComPPI
CNOT1 RARA 14525934 16778766 N/A two hybrid HPRD
CNOT1 CNOT1 22977175 24234451 N/A x-ray crystallography IntAct
TANK CNOT1 24234451 30561431 association virotrap IntAct
CNOT1 CCR4 10490603 11023781 11733989 16263706 20386698 21669201 22959269 27898060 9463387 N/A N/A OmniPath

Visualization










  Return