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GENE：TRIB1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TRIB1
FullNmae tribbles pseudokinase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16891
EnsembleID ENSG00000173334
Uniprot Q96RU8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TRIB1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TRIB1 GO:0004860,GO:0005515,GO:0005634,GO:0005634,GO:0005737,GO:0005829,GO:0006469,GO:0007254,GO:0014912,GO:0031434,GO:0031434,GO:0031625,GO:0031665,GO:0032436,GO:0032436,GO:0032496,GO:0032496,GO:0043405,GO:0043405,GO:0043433,GO:0043433,GO:0045645,GO:0045651,GO:0045659,GO:0048662,GO:0055106,GO:0061629

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 TRIB1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 TRIB1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 TRIB1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 TRIB1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 TRIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TRIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TRIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 TRIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TRIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TRIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TRIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 TRIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TRIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TRIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TRIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 TRIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC TRIB1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003380CC TRIB1 19296470 rna interference,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00003380CC TRIB1 19296470 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000237AF9 TRIB1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000157026 TRIB1 20371350 25416803 26701625 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS0000122ED0 TRIB1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 TRIB1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000184017 TRIB1 24382668 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00003E226A TRIB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 TRIB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005E1A16 TRIB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C TRIB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 TRIB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000031E12 TRIB1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001597DC TRIB1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003BD367 TRIB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 TRIB1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 TRIB1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 TRIB1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 TRIB1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 TRIB1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000137EDE TRIB1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000019907A TRIB1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000035AC91 TRIB1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000292B1 TRIB1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000041E780 TRIB1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000521626 TRIB1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000002569A TRIB1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001A4ABF TRIB1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 TRIB1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000022B729 TRIB1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005194EC TRIB1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002CEB74 TRIB1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D TRIB1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 TRIB1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000070B1D TRIB1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 TRIB1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001A405B TRIB1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004C5774 TRIB1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002E92A8 TRIB1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003758F0 TRIB1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000024CEE0 TRIB1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001C308D TRIB1 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CD81 TRIB1 25361965 interaction type N/A PTMCode2
TRIB1 CD81 25361965 interaction type N/A PTMCode2
ITGA3 TRIB1 25361965 interaction type N/A PTMCode2
TRIB1 ITGA3 25361965 interaction type N/A PTMCode2
TRIB1 ITGB1 25361965 interaction type N/A PTMCode2
ITGB1 TRIB1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
JUNB TRIB1 25348397 N/A physical interaction ComPPI
FOSL2 TRIB1 25348397 N/A physical interaction ComPPI
COP1 TRIB1 25348397 N/A physical interaction ComPPI
CEBPB TRIB1 17724128 24234451 25348397 27898060 physical association two hybrid ComPPI,IntAct,OmniPath
MAP2K4 TRIB1 14525934 15299019 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,in vivo ComPPI,HPRD,IntAct
MAP2K1 TRIB1 14525934 15299019 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,in vivo ComPPI,HPRD,IntAct
TRIB1 MAP2K7 25348397 N/A in vivo ComPPI
TRIB1 ALOX12 10727209 14525934 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
TRIB1 ELAVL1 25348397 N/A physical interaction ComPPI
TRIB1 STK40 24234451 25348397 25852190 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIB1 LLGL1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIB1 PCDH1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIB1 BECN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIB1 STK17B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIB1 RASSF8 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIB1 MORC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIB1 SLAIN2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIB1 HNRNPA1L2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIB1 FOS 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TRIB1 MALT1 25348397 N/A physical interaction ComPPI
TRIB1 PECR 25348397 N/A physical interaction ComPPI
TRIB1 DET1 25348397 N/A physical interaction ComPPI
TRIB1 ISCA1 25348397 N/A physical interaction ComPPI
TRIB1 TRIB2 25348397 N/A physical interaction ComPPI
TRIB1 UBE2E1 25348397 N/A physical interaction ComPPI
TRIB1 CEBPA 25348397 26455797 27898060 N/A isothermal titration calorimetry,pull down,physical interaction ComPPI,OmniPath

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