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GENE：PNN

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PNN
FullNmae pinin, desmosome associated protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9162
EnsembleID ENSG00000100941
Uniprot Q9H307

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PNN mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PNN autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PNN GO:0000398,GO:0003677,GO:0003723,GO:0005198,GO:0005515,GO:0005654,GO:0005882,GO:0005886,GO:0005911,GO:0007155,GO:0016020,GO:0016607,GO:0030057,GO:0071013,GO:0071013

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PNN hsa:5411 path:hsa03013 Nucleocytoplasmic transport - Homo sapiens (human)
PNN hsa:5411 path:hsa03015 mRNA surveillance pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PNN CTBP1 15542832 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
PNN NFKBIL1 17353931 23180781 physical association anti tag coimmunoprecipitation,affinity technology InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 PNN 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PNN 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PNN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PNN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PNN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PNN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PNN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PNN 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000171CD1 PNN 18362358 rna interference,inhibition array technology miRSponge
URS0000171CD1 PNN 18362358 25416803 mrna cleavage,inhibition array technology TarBase
URS0000272039 PNN 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00002152A8 PNN 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000183BED PNN 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000070B1D PNN 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD PNN 22012620 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS00002D2333 PNN 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000023133F PNN 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 PNN 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003808EC PNN 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0BB4 PNN 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000004CA3 PNN 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00005CCD18 PNN 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 PNN 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000042619A PNN 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003CCBB9 PNN 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PNN SF3A2 25361965 interaction type N/A PTMCode2
SF3A2 PNN 25361965 interaction type N/A PTMCode2
PNN CTBP1 25361965 interaction type N/A PTMCode2
CTBP1 PNN 25361965 interaction type N/A PTMCode2
PNN KRT8 25361965 interaction type N/A PTMCode2
KRT8 PNN 25361965 interaction type N/A PTMCode2
PNN CTBP2 25361965 interaction type N/A PTMCode2
CTBP2 PNN 25361965 interaction type N/A PTMCode2
PNN RNPS1 25361965 interaction type N/A PTMCode2
RNPS1 PNN 25361965 interaction type N/A PTMCode2
PNN PRPF4B 25361965 interaction type N/A PTMCode2
PRPF4B PNN 25361965 interaction type N/A PTMCode2
PNN ZCCHC17 25361965 interaction type N/A PTMCode2
ZCCHC17 PNN 25361965 interaction type N/A PTMCode2
PNN KRT18 25361965 interaction type N/A PTMCode2
KRT18 PNN 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KRT18 PNN 25348397 N/A two hybrid,physical interaction,in vitro ComPPI
UBE2I PNN 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
SNW1 PNN 18794151 20467437 24234451 25348397 30021884 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,cross-linking study,physical interaction ComPPI,IntAct
CDC5L PNN 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
KRT19 PNN 25348397 N/A two hybrid,physical interaction,in vitro ComPPI
SAP18 PNN 22388736 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMC3 PNN 25348397 N/A physical interaction ComPPI
YWHAG PNN 15324660 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,coimmunoprecipitation,in vivo ComPPI,IntAct
SNIP1 PNN 18794151 24234451 25348397 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
SF3A2 PNN 17332742 24234451 25348397 physical association affinity chromatography technology,physical interaction ComPPI,IntAct
RBM39 PNN 25348397 N/A physical interaction ComPPI
RBBP6 PNN 25348397 N/A physical interaction ComPPI
CTBP1 PNN 25348397 N/A physical interaction,in vitro,in vivo ComPPI
CTBP2 PNN 25348397 N/A in vivo ComPPI
U2AF2 PNN 25348397 N/A physical interaction ComPPI
YWHAZ PNN 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DLD PNN 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
NTRK1 PNN 25348397 N/A physical interaction ComPPI
PRPF40A PNN 25348397 N/A physical interaction ComPPI
PDPK1 PNN 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SREK1 PNN 25348397 N/A physical interaction ComPPI
CLK2 PNN 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CSNK2A1 PNN 22113938 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
MDK PNN 25348397 N/A physical interaction ComPPI
PDHA1 PNN 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
XAB2 PNN 25348397 N/A physical interaction ComPPI
NOS1AP PNN 25348397 N/A physical interaction ComPPI
CNGB1 PNN 25348397 N/A two hybrid ComPPI
GRK5 PNN 25348397 N/A physical interaction ComPPI
TOPORS PNN 25348397 N/A physical interaction ComPPI
SRPK1 PNN 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CSNK2A2 PNN 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
EPB41L3 PNN 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EPB41L2 PNN 25348397 N/A physical interaction ComPPI
CDK2 PNN 25348397 N/A physical interaction ComPPI
VAMP8 PNN 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
DNM1L PNN 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
CUL7 PNN 25348397 N/A physical interaction ComPPI
HDAC11 PNN 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EDA PNN 25348397 N/A physical interaction ComPPI
BCLAF1 PNN 18794151 24234451 25348397 colocalization molecular sieving,physical interaction ComPPI,IntAct
BARD1 PNN 25348397 N/A physical interaction ComPPI
VANGL2 PNN 25348397 N/A physical interaction ComPPI
ACIN1 PNN 24234451 25348397 30021884 physical association cross-linking study,physical interaction ComPPI,IntAct
SRPK2 PNN 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PRPF4B PNN 23602568 24234451 25348397 association two hybrid,physical interaction,in vivo,tandem affinity purification ComPPI,IntAct
ZMYND11 PNN 25348397 N/A physical interaction ComPPI
VANGL1 PNN 25348397 N/A physical interaction ComPPI
RPL6 PNN 25348397 N/A physical interaction ComPPI
CASC3 PNN 25348397 N/A physical interaction ComPPI
PARK7 PNN 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SRSF4 PNN 25348397 N/A two hybrid,physical interaction,in vivo ComPPI
MAGOH PNN 23084401 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PNN SRRM2 25348397 N/A two hybrid,physical interaction,in vivo ComPPI
PNN RNPS1 14517304 14729963 17353931 22388736 24234451 25348397 26344197 27898060 physical association anti bait coimmunoprecipitation,molecular sieving,pull down,physical interaction,in vitro,in vivo ComPPI,IntAct,OmniPath
PNN PNISR 25348397 N/A two hybrid,physical interaction,in vivo ComPPI
PNN PPIG 15358154 25348397 27898060 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI,OmniPath
PNN ZCCHC17 12893261 25348397 27898060 N/A two hybrid,physical interaction ComPPI,OmniPath
PNN DYNC1I2 25348397 N/A two hybrid ComPPI
PNN KRT8 25348397 N/A two hybrid,physical interaction,in vitro ComPPI
PNN NFKBIL1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PNN TCEA2 25348397 N/A physical interaction ComPPI
PNN SIRT7 25348397 N/A physical interaction ComPPI
PNN HNRNPA1 25348397 N/A physical interaction ComPPI
PNN PCLAF 25348397 N/A physical interaction ComPPI
PNN OBSL1 25348397 N/A physical interaction ComPPI
PNN LUZP4 25348397 N/A physical interaction ComPPI
PNN TRA2A 25348397 N/A physical interaction ComPPI
PNN RALYL 25348397 N/A physical interaction ComPPI
PNN FAM9A 25348397 N/A physical interaction ComPPI
PNN LUC7L 25348397 N/A physical interaction ComPPI
PNN LUC7L2 25348397 N/A physical interaction ComPPI
PNN PTGER3 25348397 N/A physical interaction ComPPI
PNN NKAPD1 25348397 N/A physical interaction ComPPI
PNN DENND2D 25348397 N/A physical interaction ComPPI
PNN ZC3H18 25348397 N/A physical interaction ComPPI
PNN IFI16 25348397 N/A physical interaction ComPPI
PNN NDUFAF1 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PNN USP37 25348397 N/A physical interaction ComPPI
PNN CCDC9 25348397 N/A physical interaction ComPPI
PNN ZC3H14 25348397 N/A physical interaction ComPPI
PNN CAMKV 25348397 N/A physical interaction ComPPI
PNN AKAP17A 25348397 N/A physical interaction ComPPI
PNN CLK3 25348397 N/A physical interaction ComPPI
PNN PIP4K2A 25348397 N/A physical interaction ComPPI
PNN SCAF1 25348397 N/A physical interaction ComPPI
PNN NCBP3 24234451 25348397 26382858 association pull down,physical interaction ComPPI,IntAct
PNN RSBN1L 25348397 N/A physical interaction ComPPI
PNN THRAP3 18794151 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PNN PES1 25348397 N/A physical interaction ComPPI
PNN WSB2 25348397 N/A physical interaction ComPPI
PNN RBM22 25348397 N/A physical interaction ComPPI
PNN ELAVL2 25348397 N/A physical interaction ComPPI
PNN CDC40 25348397 N/A physical interaction ComPPI
PNN CFAP20 25348397 N/A physical interaction ComPPI
PNN NKTR 25348397 N/A physical interaction ComPPI
PNN FYTTD1 25348397 N/A physical interaction ComPPI
PNN PPIE 25348397 N/A physical interaction ComPPI
PNN NKAP 25348397 N/A physical interaction ComPPI
PNN SMOC1 25348397 N/A physical interaction ComPPI
PNN RSBN1 25348397 N/A physical interaction ComPPI
PNN CRNKL1 25348397 N/A physical interaction ComPPI
PNN ISY1 25348397 N/A physical interaction ComPPI
PNN GPALPP1 25348397 N/A physical interaction ComPPI
PNN SRSF10 25348397 N/A physical interaction ComPPI
PNN DHX8 25348397 N/A physical interaction ComPPI
PNN AQR 25348397 N/A physical interaction ComPPI
PNN COX15 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PNN DLST 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PNN MED19 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PNN TOE1 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PNN FOS 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
PNN KRT27 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PNN PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
SRRM1 PNN 25348397 N/A physical interaction ComPPI
EIF4A3 PNN 23084401 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SARNP PNN 25348397 N/A physical interaction ComPPI
DDX41 PNN 24234451 25348397 25920683 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MKI67 PNN 24234451 26949251 association anti tag coimmunoprecipitation IntAct
PNN PPIAL4F 24234451 30021884 physical association cross-linking study IntAct
PNN EXOSC2 24234451 30021884 physical association cross-linking study IntAct
PNN C2ORF49 24234451 30021884 physical association cross-linking study IntAct

Visualization










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