GENE：RLF
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | RLF |
| FullNmae | RLF zinc finger |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:10025 |
| EnsembleID | ENSG00000117000 |
| Uniprot | Q13129 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| RLF | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| RLF | GO:0000981,GO:0001228,GO:0003677,GO:0005515,GO:0005634,GO:0005634,GO:0006357,GO:0044030,GO:0045893,GO:0045944,GO:0046872 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | RLF | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | RLF | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | RLF | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| HIF1A | RLF | 18971253 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| YBX1 | RLF | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | RLF | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | RLF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | RLF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | RLF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | RLF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | RLF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | RLF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | RLF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | RLF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | RLF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | RLF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000ED600 | RLF | 20215506 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000016FF9C | RLF | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
| URS0000070B1D | RLF | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00001CC379 | RLF | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00002075FA | RLF | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000003ABC4 | RLF | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000018C928 | RLF | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000236310 | RLF | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| H2BC4 | RLF | 25348397 | N/A | physical interaction | ComPPI |
| PRPF40A | RLF | 14525934 15231748 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
| CLK1 | RLF | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPL | RLF | 25348397 | N/A | physical interaction | ComPPI |
| CNKSR2 | RLF | 25348397 | N/A | physical interaction | ComPPI |
| RIT1 | RLF | 10545207 14525934 24234451 25348397 | physical association | two hybrid,pull down,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
| RLF | RIT2 | 10545207 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| RLF | GCH1 | 14525934 16696853 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
| RLF | ALB | 15174051 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| RLF | H2BC11 | 25348397 | N/A | physical interaction | ComPPI |
| RLF | TRIM11 | 25348397 | N/A | physical interaction | ComPPI |
| RLF | SUMO3 | 17000644 24234451 25348397 | association | affinity chromatography technology | ComPPI,IntAct |
| RLF | ZNF24 | 20195357 24234451 25348397 | physical association | display technology | ComPPI,IntAct |
| RLF | CBX3 | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| CBX5 | RLF | 20562864 24234451 25348397 27705803 | association | anti tag coimmunoprecipitation,tandem affinity purification | ComPPI,IntAct |
| H3C1 | RLF | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | RLF | 10545207 27898060 | N/A | N/A | OmniPath |
| RLF | RIN1 | 10545207 27898060 | stimulant | N/A | OmniPath |
| RLF | RIT1 | 10545207 27898060 | stimulant | N/A | OmniPath |