GENE：TTBK2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | TTBK2 |
| FullNmae | tau tubulin kinase 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:19141 |
| EnsembleID | ENSG00000128881 |
| Uniprot | Q6IQ55 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| TTBK2 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| TTBK2 | GO:0000226,GO:0004672,GO:0004674,GO:0004674,GO:0004674,GO:0005515,GO:0005524,GO:0005615,GO:0005634,GO:0005634,GO:0005737,GO:0005814,GO:0005829,GO:0005829,GO:0007026,GO:0007165,GO:0007224,GO:0018105,GO:0018105,GO:0019894,GO:0021549,GO:0021681,GO:0021935,GO:0030334,GO:0035869,GO:0035869,GO:0035869,GO:0036064,GO:0036064,GO:0048156,GO:0050321,GO:0050321,GO:0051010,GO:0060271,GO:0060271,GO:0060271,GO:0106310,GO:1902817,GO:1904527 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | TTBK2 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | TTBK2 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | TTBK2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | TTBK2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | TTBK2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | TTBK2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | TTBK2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | TTBK2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | TTBK2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GABARAPL2 | TTBK2 | 20562859 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| MCM2 | TTBK2 | 25348397 | N/A | physical interaction | ComPPI |
| CRK | TTBK2 | 19380743 24234451 25348397 | association | tandem affinity purification | ComPPI,IntAct |
| COPS5 | TTBK2 | 25348397 | N/A | physical interaction | ComPPI |
| CFTR | TTBK2 | 25348397 | N/A | physical interaction | ComPPI |
| PTEN | TTBK2 | 25348397 | N/A | physical interaction | ComPPI |
| ZWINT | TTBK2 | 25348397 | N/A | physical interaction | ComPPI |
| KLHL12 | TTBK2 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| TTBK2 | SV2A | 25673844 27898060 | N/A | N/A | OmniPath |
| TTBK2 | KIF2A | 26323690 27898060 | N/A | N/A | OmniPath |