Gene Information gene info

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GENE：THOC5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol THOC5
FullNmae THO complex subunit 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19074
EnsembleID ENSG00000100296
Uniprot Q13769

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
THOC5 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
THOC5 GO:0000346,GO:0000347,GO:0000445,GO:0000445,GO:0000781,GO:0003729,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0006397,GO:0006406,GO:0006406,GO:0008380,GO:0030224,GO:0032786,GO:0032786,GO:0046784,GO:0060215,GO:2000002

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
THOC5 hsa:8563 path:hsa03013 Nucleocytoplasmic transport - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 THOC5 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 THOC5 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 THOC5 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 THOC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA THOC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF THOC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 THOC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 THOC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 THOC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 THOC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000122ED0 THOC5 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00003D5391 THOC5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 THOC5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000065D58 THOC5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 THOC5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000759B6A THOC5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 THOC5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB14 THOC5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC4BD THOC5 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00006DE17B THOC5 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000005CE28 THOC5 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000021202F THOC5 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000D4AB5 THOC5 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075BDAA THOC5 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075CC78 THOC5 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075D814 THOC5 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001012BC THOC5 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PDGFRB THOC5 22135298 phosphorylation N/A PhosphoSite
PRKCA THOC5 22135298 phosphorylation N/A PhosphoSite
CSF1R THOC5 25361965 interaction type N/A PTMCode2
THOC5 CSF1R 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MAGOHB THOC5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPIL1 THOC5 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
VIM THOC5 25348397 N/A physical interaction ComPPI
LSM3 THOC5 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SMAD4 THOC5 25348397 N/A physical interaction ComPPI
PRKCA THOC5 14525934 15221008 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
LIG4 THOC5 25348397 N/A physical interaction ComPPI
TAP1 THOC5 19165146 24234451 25348397 physical association two hybrid,pull down ComPPI,IntAct
PDGFRA THOC5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FMNL1 THOC5 25348397 N/A physical interaction ComPPI
CSNK2A1 THOC5 22113938 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
THOC5 THOC7 14525934 19059247 24234451 25348397 26496610 colocalization,association,physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,fluorescence microscopy,in vitro ComPPI,HPRD,IntAct
THOC5 CSF1R 10597251 14525934 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
THOC5 DDX39B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 ALYREF 19165146 23299939 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
THOC5 THOC2 19165146 23299939 24234451 25348397 26496610 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 THOC1 19059247 19165146 22365833 23299939 24234451 25348397 26496610 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,physical interaction,fluorescence microscopy ComPPI,IntAct
THOC5 THOC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 THOC6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 NCBP1 25348397 N/A physical interaction ComPPI
THOC5 NXF1 23299939 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 DDX23 25348397 N/A physical interaction ComPPI
THOC5 ZC3H15 25348397 N/A physical interaction ComPPI
THOC5 ZKSCAN5 25348397 N/A physical interaction ComPPI
THOC5 RRP9 25348397 N/A physical interaction ComPPI
THOC5 UTRN 25348397 N/A physical interaction ComPPI
THOC5 ZPR1 25348397 N/A physical interaction ComPPI
THOC5 ZNF606 25348397 N/A physical interaction ComPPI
THOC5 TJP2 25348397 N/A physical interaction ComPPI
THOC5 ZNF830 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
THOC5 RNF2 25348397 N/A physical interaction ComPPI
THOC5 LUZP4 25348397 N/A physical interaction ComPPI
THOC5 HSPB1 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
THOC5 TJP1 25348397 N/A physical interaction ComPPI
THOC5 GTF2F1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 RPL6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 RPL22 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 RPL27A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 HSF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 BCLAF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 NCBP3 24234451 25348397 26382858 26496610 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
THOC5 NEMF 25348397 N/A physical interaction ComPPI
THOC5 ZC3H11A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 DDX39A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 KIF1C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 MRPS27 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 SIRT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 CCDC9 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 CHTOP 23299939 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 WDR74 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 DDX24 25348397 N/A physical interaction ComPPI
THOC5 KIAA1522 25348397 N/A physical interaction ComPPI
THOC5 MYO1G 25348397 N/A physical interaction ComPPI
THOC5 ZC3H14 25348397 N/A physical interaction ComPPI
THOC5 KLF16 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 FYTTD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 POLDIP3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 SERPINB12 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 C19ORF47 25348397 N/A physical interaction ComPPI
THOC5 MRPL12 25348397 N/A physical interaction ComPPI
THOC5 SLC25A10 25348397 N/A physical interaction ComPPI
XPO4 THOC5 25348397 N/A physical interaction ComPPI
EIF4A3 THOC5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IMP4 THOC5 25348397 N/A physical interaction ComPPI
SARNP THOC5 25348397 N/A physical interaction ComPPI
UBR7 THOC5 25348397 N/A physical interaction ComPPI
CSW THOC5 25348397 N/A two hybrid ComPPI
MKI67 THOC5 24234451 26949251 association anti tag coimmunoprecipitation IntAct
OXTR THOC5 24234451 28298427 physical association ubiquitin reconstruction IntAct
NCBP2 THOC5 24234451 26382858 association pull down IntAct
PRKCA THOC5 15221008 20068231 27898060 stimulant N/A OmniPath
PDGFRB THOC5 23032722 27898060 N/A N/A OmniPath

Visualization










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