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GENE：TMEM14A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TMEM14A
FullNmae transmembrane protein 14A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:21076
EnsembleID ENSG00000096092
Uniprot Q9Y6G1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TMEM14A autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TMEM14A apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TMEM14A apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
TMEM14A GO:0005515,GO:0005789,GO:0006915,GO:0031966,GO:0031966,GO:0043066,GO:0070453,GO:1901029

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 TMEM14A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 TMEM14A 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 TMEM14A 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 TMEM14A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TMEM14A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TMEM14A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TMEM14A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TMEM14A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TMEM14A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TMEM14A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TMEM14A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000508C13 TMEM14A N/A 15685193 rna interference,inhibition array technology miRSponge
URS0000508C13 TMEM14A 15685193 25416803 mrna cleavage,inhibition array technology,array technology,experimental interaction detection TarBase
URS0000521626 TMEM14A 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS00003BBF48 TMEM14A 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase

Source Target Pmid Interactiontype Methods Database
LMNA TMEM14A 25348397 N/A physical interaction ComPPI
SLC7A1 TMEM14A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TMEM14A ELAVL1 25348397 N/A physical interaction ComPPI
TMEM14A CREB3 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TMEM14A USP18 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TMEM14A MTNR1A 24234451 25348397 26514267 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
TMEM14A MTNR1B 24234451 25348397 26514267 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
TMEM14A SRPK2 23602568 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
TMEM14A CREB3L1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TMEM14A CXCR3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TMEM14A PDZK1IP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

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