Gene Information gene info

GENE:CBFA2T2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CBFA2T2
FullNmae CBFA2/RUNX1 partner transcriptional co-repressor 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1536
EnsembleID ENSG00000078699
Uniprot O43439

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CBFA2T2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CBFA2T2 GO:0000122,GO:0003714,GO:0003714,GO:0003714,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0006351,GO:0010976,GO:0010977,GO:0045746,GO:0045892,GO:0045892,GO:0046872,GO:0060575

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR CBFA2T2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 CBFA2T2 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ESR1 CBFA2T2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 CBFA2T2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 CBFA2T2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 CBFA2T2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 CBFA2T2 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 CBFA2T2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 CBFA2T2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CBFA2T2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CBFA2T2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CBFA2T2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CBFA2T2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CBFA2T2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 CBFA2T2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000600E6 CBFA2T2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003FBC84 CBFA2T2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC4BD CBFA2T2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 CBFA2T2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 CBFA2T2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000007F792 CBFA2T2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD002 CBFA2T2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001496AE CBFA2T2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075ABF4 CBFA2T2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075AB14 CBFA2T2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 CBFA2T2 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CBFA2T2 RUNX1 25361965 interaction type N/A PTMCode2
RUNX1 CBFA2T2 25361965 interaction type N/A PTMCode2
CBFA2T2 CBFB 25361965 interaction type N/A PTMCode2
CBFB CBFA2T2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MDFI CBFA2T2 14525934 16189514 19060904 21516116 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PRDM14 CBFA2T2 24234451 25348397 25416956 27281218 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,molecular sieving,physical interaction,mammalian protein protein interaction trap,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRKDC CBFA2T2 24234451 25348397 27281218 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC3 CBFA2T2 25348397 N/A physical interaction ComPPI
NCOR2 CBFA2T2 25348397 N/A in vitro,in vivo ComPPI
NCOR1 CBFA2T2 10675041 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SIN3A CBFA2T2 12242670 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CBFA2T3 CBFA2T2 12242670 14525934 24234451 25348397 27281218 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
HNRNPL CBFA2T2 25348397 N/A physical interaction ComPPI
PDP1 CBFA2T2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CBFA2T2 NTAQ1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CBFA2T2 CBFB 14525934 25348397 9447981 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CBFA2T2 ZNF652 14525934 16966434 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,in vivo ComPPI,HPRD,IntAct
CBFA2T2 RERE 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
CBFA2T2 RUNX1 10675041 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CBFA2T2 RUNX1T1 25348397 N/A physical interaction ComPPI
CBFA2T2 TAL1 25348397 N/A physical interaction ComPPI
CBFA2T2 GTF2E1 25348397 N/A physical interaction ComPPI
CBFA2T2 FBXL19 25348397 N/A physical interaction ComPPI
CBFA2T2 ATN1 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
CBFA2T2 ATXN1L 25348397 N/A physical interaction ComPPI
CBFA2T2 APP 25348397 N/A physical interaction ComPPI
CBFA2T2 LBP 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CBFA2T2 NOTCH3 25348397 N/A physical interaction ComPPI
CBFA2T2 PRDM6 25348397 N/A physical interaction ComPPI
CBFA2T2 TCF4 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
CBFA2T2 CCDC88A 24234451 25348397 27281218 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CBFA2T2 RNF2 24234451 25348397 27281218 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CBFA2T2 ANKFY1 24234451 25348397 27281218 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CBFA2T2 ZBTB2 24234451 25348397 27281218 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CBFA2T2 CCAR2 24234451 25348397 27281218 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CBFA2T2 MAGED2 24234451 25348397 27281218 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CBFA2T2 STAT3 24234451 25348397 27281218 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CBFA2T2 TRIM33 20603019 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TAL2 CBFA2T2 25348397 N/A physical interaction ComPPI
ID3 CBFA2T2 25348397 N/A physical interaction ComPPI
TCP1 CBFA2T2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NEUROG1 CBFA2T2 25348397 N/A physical interaction ComPPI
CBFA2T2 CBFA2T2 24234451 25416956 physical association two hybrid array IntAct

Visualization