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GENE：COPS7B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol COPS7B
FullNmae COP9 signalosome subunit 7B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16760
EnsembleID ENSG00000144524
Uniprot Q9H9Q2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
COPS7B autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
COPS7B GO:0000338,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005829,GO:0008180,GO:0008180,GO:0008180,GO:0010387,GO:0045116,GO:2000434

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NEDD8 COPS7B 21145461 23180781 physical association anti tag coimmunoprecipitation InnateDB
APP COPS7B 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 COPS7B 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 COPS7B 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 COPS7B 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 COPS7B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA COPS7B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF COPS7B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 COPS7B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 COPS7B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS COPS7B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A COPS7B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002152A8 COPS7B 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000065D58 COPS7B 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000048BA36 COPS7B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000037E170 COPS7B 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C3AC1 COPS7B 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC COPS7B 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002E177F COPS7B 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 COPS7B 22927820 23824327 24906430 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 COPS7B 22927820 23313552 23824327 24906430 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 COPS7B 23824327 25416803 27418678 28735896 mrna cleavage,inhibition clip TarBase
URS0000065FDF COPS7B 25416803 27418678 28735896 mrna cleavage,inhibition clip TarBase
URS000018D2BE COPS7B 25416803 27418678 28735896 mrna cleavage,inhibition clip TarBase
URS000025EABA COPS7B 25416803 27418678 28735896 mrna cleavage,inhibition clip TarBase
URS00002C02E4 COPS7B 25416803 27418678 28735896 mrna cleavage,inhibition clip TarBase
URS000075ABF4 COPS7B 25416803 27418678 28735896 mrna cleavage,inhibition clip TarBase
URS000005A8ED COPS7B 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS000002569A COPS7B 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS000028D811 COPS7B 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS0000572E11 COPS7B 25416803 28735896 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NMI COPS7B 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BEX5 COPS7B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CUL5 COPS7B 25348397 N/A physical interaction ComPPI
KRAS COPS7B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FBXO17 COPS7B 25348397 N/A physical interaction ComPPI
DCUN1D1 COPS7B 25348397 N/A physical interaction ComPPI
JUNB COPS7B 25348397 N/A physical interaction ComPPI
EIF3E COPS7B 12220626 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
APPBP2 COPS7B 25348397 N/A physical interaction ComPPI
SPAG5 COPS7B 25348397 N/A physical interaction ComPPI
COPS5 COPS7B 18850735 19615732 20399188 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
COP1 COPS7B 25348397 N/A physical interaction ComPPI
CUL3 COPS7B 25348397 N/A physical interaction ComPPI
YWHAZ COPS7B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBB COPS7B 25348397 N/A physical interaction ComPPI
DLD COPS7B 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PRMT1 COPS7B 25348397 N/A physical interaction ComPPI
BTRC COPS7B 25348397 N/A physical interaction ComPPI
EWSR1 COPS7B 25348397 N/A physical interaction ComPPI
COPS2 COPS7B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
NEDD8 COPS7B 25348397 N/A physical interaction ComPPI
CUL2 COPS7B 25348397 N/A physical interaction ComPPI
CUL4B COPS7B 25348397 N/A physical interaction ComPPI
CUL1 COPS7B 25348397 N/A physical interaction ComPPI
CUL4A COPS7B 25348397 N/A physical interaction ComPPI
COPS3 COPS7B 20399188 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
COPS4 COPS7B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GPS1 COPS7B 20399188 24234451 25348397 physical association electron microscopy,molecular sieving,physical interaction ComPPI,IntAct
COPS6 COPS7B 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction,inference by socio-affinity scoring ComPPI,IntAct
COPS7A COPS7B 25348397 N/A physical interaction ComPPI
COPS8 COPS7B 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
CDK2AP1 COPS7B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPIA COPS7B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PCMT1 COPS7B 25348397 N/A physical interaction ComPPI
PMF1 COPS7B 12020345 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
SARS2 COPS7B 25348397 N/A physical interaction ComPPI
ELAVL1 COPS7B 25348397 N/A physical interaction ComPPI
DDB2 COPS7B 25348397 N/A physical interaction ComPPI
DDB1 COPS7B 25348397 N/A physical interaction ComPPI
FBXO7 COPS7B 25348397 N/A physical interaction ComPPI
ASPM COPS7B 25348397 N/A physical interaction ComPPI
COPS7B DCAF1 25348397 N/A physical interaction ComPPI
COPS7B LRR1 25348397 N/A physical interaction ComPPI
COPS7B APP 25348397 N/A physical interaction ComPPI
COPS7B IRF5 25348397 N/A physical interaction ComPPI
COPS7B FBXW4 25348397 N/A physical interaction ComPPI
COPS7B FBXO6 25348397 N/A physical interaction ComPPI
COPS7B HEXIM1 25348397 N/A physical interaction ComPPI
COPS7B USP24 25348397 N/A physical interaction ComPPI
COPS7B ERP44 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COPS7B MYH7B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COPS7B USP15 25348397 N/A physical interaction ComPPI
COPS7B SUN2 25348397 N/A physical interaction ComPPI
COPS7B BTBD1 25348397 N/A physical interaction ComPPI
COPS7B DST 25348397 N/A physical interaction ComPPI
COPS7B APBB3 25348397 N/A physical interaction ComPPI
COPS7B KLHL10 25348397 N/A physical interaction ComPPI
COPS7B DET1 25348397 N/A physical interaction ComPPI
COPS7B UBE3A 25348397 N/A physical interaction ComPPI
COPS7B FEM1B 25348397 N/A physical interaction ComPPI
COPS7B KNSTRN 25348397 N/A physical interaction ComPPI
COPS7B DCAF4 25348397 N/A physical interaction ComPPI
COPS7B DCAF11 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
COPS7B HECTD3 25348397 N/A physical interaction ComPPI
COPS7B UBE2M 25348397 N/A physical interaction ComPPI
COPS7B ZZEF1 25348397 N/A physical interaction ComPPI
COPS7B DENR 25348397 N/A physical interaction ComPPI
COPS7B FAM98A 25348397 N/A physical interaction ComPPI
COPS7B DCAF4L2 25348397 N/A physical interaction ComPPI
COPS7B CRBN 25348397 N/A physical interaction ComPPI
DDA1 COPS7B 25348397 N/A physical interaction ComPPI
SYCE3 COPS7B 25348397 N/A physical interaction ComPPI

Visualization










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