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GENE：NCOA6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NCOA6
FullNmae nuclear receptor coactivator 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15936
EnsembleID ENSG00000198646
Uniprot Q14686

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NCOA6 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NCOA6 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NCOA6 GO:0003682,GO:0003713,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005667,GO:0005667,GO:0005829,GO:0006352,GO:0006974,GO:0007420,GO:0007507,GO:0009725,GO:0019899,GO:0030099,GO:0030331,GO:0030374,GO:0030374,GO:0035097,GO:0035097,GO:0043231,GO:0044666,GO:0045893,GO:0045944,GO:0045944,GO:0046965,GO:0046966

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NCOA6 CEBPA 11302752 23180781 physical association anti tag coimmunoprecipitation InnateDB
NCOA6 ATF2 14734562 23180781 physical association anti tag coimmunoprecipitation InnateDB
NCOA6 CSF3R 14734562 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR NCOA6 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
GATA3 NCOA6 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 NCOA6 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 NCOA6 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 NCOA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NCOA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NCOA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NCOA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NCOA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NCOA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF NCOA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PPARG NCOA6 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000184017 NCOA6 20065103 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000184017 NCOA6 20065103 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00002152A8 NCOA6 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000CBE63 NCOA6 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000035CC3E NCOA6 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000512C88 NCOA6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000CF1D2 NCOA6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004AC389 NCOA6 25074381 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000285DCB NCOA6 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MAPK1 NCOA6 22135298 phosphorylation N/A PhosphoSite
ASH2L NCOA6 25361965 interaction type N/A PTMCode2
NCOA6 ASH2L 25361965 interaction type N/A PTMCode2
ATF2 NCOA6 25361965 interaction type N/A PTMCode2
NCOA6 ATF2 25361965 interaction type N/A PTMCode2
GHR NCOA6 25361965 interaction type N/A PTMCode2
NCOA6 GHR 25361965 interaction type N/A PTMCode2
RBBP5 NCOA6 25361965 interaction type N/A PTMCode2
NCOA6 RBBP5 25361965 interaction type N/A PTMCode2
WDR5 NCOA6 25361965 interaction type N/A PTMCode2
NCOA6 WDR5 25361965 interaction type N/A PTMCode2
ESR1 NCOA6 25361965 interaction type N/A PTMCode2
NCOA6 ESR1 25361965 interaction type N/A PTMCode2
DPY30 NCOA6 25361965 interaction type N/A PTMCode2
NCOA6 DPY30 25361965 interaction type N/A PTMCode2
NR3C1 NCOA6 25361965 interaction type N/A PTMCode2
NCOA6 NR3C1 25361965 interaction type N/A PTMCode2
SRC NCOA6 25361965 interaction type N/A PTMCode2
NCOA6 SRC 25361965 interaction type N/A PTMCode2
NCOA6 PAXIP1 25361965 interaction type N/A PTMCode2
PAXIP1 NCOA6 25361965 interaction type N/A PTMCode2
NCOA6 RELA 25361965 interaction type N/A PTMCode2
RELA NCOA6 25361965 interaction type N/A PTMCode2
NCOA6 RXRA 25361965 interaction type N/A PTMCode2
RXRA NCOA6 25361965 interaction type N/A PTMCode2
ZNF335 NCOA6 25361965 interaction type N/A PTMCode2
NCOA6 ZNF335 25361965 interaction type N/A PTMCode2
TARBP2 NCOA6 25361965 interaction type N/A PTMCode2
NCOA6 TARBP2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
DPY30 NCOA6 17500065 19047629 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NPM1 NCOA6 10866662 24234451 25348397 physical association two hybrid ComPPI,IntAct
RARA NCOA6 10567404 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
RXRG NCOA6 11158331 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
TP53BP1 NCOA6 19433796 24234451 25348397 association,physical association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
GTF2A1 NCOA6 25348397 N/A physical interaction ComPPI
ACTB NCOA6 19047629 19433796 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TBP NCOA6 25348397 N/A physical interaction ComPPI
SRC NCOA6 25348397 N/A physical interaction ComPPI
PRKDC NCOA6 12519782 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
JUN NCOA6 25348397 N/A physical interaction ComPPI
RB1 NCOA6 14525934 14645241 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
HCFC1 NCOA6 23870121 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
AR NCOA6 14645241 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
CREBBP NCOA6 10866662 11158331 12482968 14525934 24234451 25348397 association,physical association two hybrid,experimental interaction detection,molecular sieving,pull down,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
SMAD2 NCOA6 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
VDR NCOA6 10866662 14525934 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
NCOA1 NCOA6 25348397 N/A physical interaction ComPPI
EP300 NCOA6 10823961 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SMAD3 NCOA6 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
MAFB NCOA6 25348397 N/A physical interaction ComPPI
RBM39 NCOA6 11704680 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
PAXIP1 NCOA6 17178841 17500065 17925232 19047629 19433796 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SRF NCOA6 25348397 N/A physical interaction ComPPI
THRA NCOA6 10866662 11158331 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
THRB NCOA6 10866662 14525934 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
NCOR2 NCOA6 25348397 N/A two hybrid,physical interaction ComPPI
MED1 NCOA6 25348397 N/A physical interaction ComPPI
PPARGC1A NCOA6 25348397 N/A physical interaction ComPPI
NR1H3 NCOA6 12724417 14525934 15604093 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
GHR NCOA6 10567404 10866662 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,in vitro ComPPI,HPRD,IntAct
UBC NCOA6 25348397 N/A physical interaction ComPPI
NR1I2 NCOA6 25348397 N/A physical interaction ComPPI
KMT2D NCOA6 12482968 17178841 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PARP1 NCOA6 12519782 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
NCOA6 PPARG 10788465 11877444 14525934 15604093 19596656 24368734 25348397 27898060 N/A anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
NCOA6 ESR2 11158331 11773444 14525934 15604093 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
NCOA6 MED23 10823961 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
NCOA6 TGS1 11517327 11912212 12754253 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
NCOA6 XRCC5 12519782 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
NCOA6 PRMT2 12039952 14525934 24234451 25348397 physical association experimental interaction detection,pull down,in vitro ComPPI,HPRD,IntAct
NCOA6 RBM14 11443112 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
NCOA6 ZNF335 12215545 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
NCOA6 TOP1 12519782 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
NCOA6 E2F1 14525934 14638867 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
NCOA6 NR1H2 11158331 12724417 14525934 15604093 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
NCOA6 CEBPA 11302752 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
NCOA6 HNF4A 25348397 N/A two hybrid,physical interaction ComPPI
NCOA6 RORC 14525934 15604093 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
NCOA6 RORB 25348397 N/A two hybrid,physical interaction ComPPI
NCOA6 ESR1 10866662 14525934 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
NCOA6 NR3C1 10866662 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
NCOA6 XRCC6 12519782 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
NCOA6 NUMA1 25348397 N/A physical interaction,in vitro ComPPI
NCOA6 KMT2C 12482968 17021013 19047629 19433796 23870121 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
NCOA6 RBBP5 12482968 17178841 17500065 17925232 19047629 19433796 23870121 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
NCOA6 LAMTOR5 25348397 N/A physical interaction ComPPI
NCOA6 FOS 25348397 N/A physical interaction ComPPI
NCOA6 NFKB1 25348397 N/A physical interaction ComPPI
NCOA6 RELA 25348397 N/A physical interaction ComPPI
NCOA6 H3C15 25348397 N/A physical interaction ComPPI
NCOA6 RXRA 10866662 11158331 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD,IntAct
NCOA6 ASCC1 25348397 N/A physical interaction ComPPI
NCOA6 CD40 25348397 N/A physical interaction ComPPI
NCOA6 TXNRD2 25348397 N/A physical interaction ComPPI
NCOA6 KDM6A 17178841 19047629 19433796 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
NCOA6 KMT2B 17021013 19047629 19433796 24234451 25348397 association,physical association anti bait coimmunoprecipitation,molecular sieving,physical interaction,ion exchange chromatography ComPPI,IntAct
NCOA6 UTY 19047629 19433796 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
NCOA6 ASH2L 12482968 17178841 17500065 17925232 19047629 19433796 23870121 24234451 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,molecular sieving,physical interaction ComPPI,IntAct
NCOA6 PAGR1 17500065 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NCOA6 NR1H4 25348397 N/A physical interaction ComPPI
NCOA6 RANBP9 25348397 N/A physical interaction ComPPI
NCOA6 FHOD1 25348397 N/A physical interaction ComPPI
NCOA6 GRIP1 25348397 N/A physical interaction ComPPI
NCOA6 RANGAP1 25348397 N/A physical interaction ComPPI
NCOA6 MED15 25348397 N/A physical interaction ComPPI
NCOA6 FUS 25348397 N/A physical interaction ComPPI
NCOA6 HSF1 25348397 N/A physical interaction ComPPI
NCOA6 NCOA2 25348397 N/A physical interaction ComPPI
NCOA6 TUBA1A 25348397 N/A physical interaction ComPPI
NCOA6 EWSR1 25348397 N/A physical interaction ComPPI
NCOA6 MAFA 25348397 N/A physical interaction ComPPI
NCOA6 FOXA1 25348397 N/A physical interaction ComPPI
NCOA6 TP53 19433796 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NCOA6 DICER1 23622242 24234451 25348397 rna cleavage cleavage assay ComPPI,IntAct
ATF2 NCOA6 11302752 14525934 14734562 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
WDR5 NCOA6 17021013 17500065 17925232 19047629 19433796 23870121 24234451 25348397 27705803 association,physical association anti bait coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
NCOA6 NCOA6 10567404 10866662 14525934 24234451 physical association two hybrid,experimental interaction detection,two hybrid HPRD,IntAct
NCOA6 NR1I3 15764585 27898060 N/A N/A OmniPath
ATF2 NCOA6 11302752 14734562 27898060 N/A N/A OmniPath
MAPK1 NCOA6 11773444 27898060 N/A N/A OmniPath

Visualization










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