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GENE：ACD

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ACD
FullNmae ACD shelterin complex subunit and telomerase recruitment factor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25070
EnsembleID ENSG00000102977
Uniprot Q96AP0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ACD mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ACD lysosomal_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ACD autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ACD cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
ACD GO:0000723,GO:0000781,GO:0000781,GO:0000783,GO:0001501,GO:0001655,GO:0005515,GO:0005654,GO:0005697,GO:0006886,GO:0007004,GO:0016233,GO:0016233,GO:0016233,GO:0016233,GO:0016233,GO:0016604,GO:0030326,GO:0031848,GO:0032202,GO:0032206,GO:0032211,GO:0032211,GO:0032211,GO:0032211,GO:0032212,GO:0035282,GO:0042162,GO:0042162,GO:0044877,GO:0051973,GO:0051973,GO:0060381,GO:0070182,GO:0070182,GO:0070187,GO:0070187,GO:0070187,GO:0070187,GO:0070187,GO:0070198,GO:0070198,GO:0070198,GO:0070200,GO:0070200

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 ACD 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
E2F4 ACD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ACD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ACD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ACD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ACD 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
NEK6 ACD 22135298 phosphorylation N/A PhosphoSite
POT1 ACD 25361965 interaction type N/A PTMCode2
ACD POT1 25361965 interaction type N/A PTMCode2
TERF1 ACD 25361965 interaction type N/A PTMCode2
ACD TERF1 25361965 interaction type N/A PTMCode2
TINF2 ACD 25361965 interaction type N/A PTMCode2
ACD TINF2 25361965 interaction type N/A PTMCode2
TERF2 ACD 25361965 interaction type N/A PTMCode2
ACD TERF2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
EIF3G ACD 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
CUL5 ACD 25348397 N/A physical interaction ComPPI
BAG3 ACD 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
LDHA ACD 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
TP53BP1 ACD 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
PAGE2 ACD 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACTB ACD 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
HSP90AB1 ACD 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
STN1 ACD 19648609 24234451 25348397 physical association anti tag coimmunoprecipitation,bimolecular fluorescence complementation ComPPI,IntAct
USP7 ACD 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
GAPDH ACD 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
PFKP ACD 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
UBB ACD 25348397 N/A pull down,physical interaction ComPPI
UBC ACD 25348397 N/A pull down,physical interaction ComPPI
RPS27A ACD 25348397 N/A pull down,physical interaction ComPPI
UBA52 ACD 25348397 N/A pull down,physical interaction ComPPI
STIP1 ACD 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
XRCC6 ACD 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
LASP1 ACD 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
DBNL ACD 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
TERT ACD 23103865 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TAGLN ACD 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
XPO1 ACD 25348397 N/A physical interaction ComPPI
TBCD ACD 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
YWHAE ACD 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
CTTN ACD 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
TUBB4B ACD 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
MDC1 ACD 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
RGS3 ACD 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
DCX ACD 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
UPF1 ACD 21829167 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
ENSA ACD 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
EIF4B ACD 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
TERF1 ACD 15383534 16880378 24234451 25348397 association,physical association anti tag coimmunoprecipitation,molecular sieving,physical interaction ComPPI,IntAct
POT1 ACD 14525934 15181449 15231715 15383534 16189514 17237767 17237768 21044950 24234451 25348397 26365187 26496610 27898060 association,physical association anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,molecular sieving,pull down,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,in vivo,bimolecular fluorescence complementation ComPPI,HPRD,IntAct,OmniPath
TINF2 ACD 14525934 15181449 15231715 16880378 21044950 24234451 25348397 25416956 25910212 26496610 association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,molecular sieving,pull down,physical interaction,mammalian protein protein interaction trap,two hybrid array,in vitro,bimolecular fluorescence complementation,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
TOMM34 ACD 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
DPYSL3 ACD 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
BRCA1 ACD 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
STUB1 ACD 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
NUDC ACD 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
TERF2 ACD 15231715 15383534 16880378 24234451 25348397 colocalization,association,physical association anti tag coimmunoprecipitation,molecular sieving,physical interaction,fluorescence microscopy ComPPI,IntAct
TERF2IP ACD 15383534 16880378 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,molecular sieving,physical interaction ComPPI,IntAct
AIPL1 ACD 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
TBC1D10A ACD 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
NCDN ACD 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD LLGL1 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ACD LRRC25 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD APOBEC3F 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD FKBP6 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD TRIM15 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD IVL 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD RBKS 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD PDLIM2 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD TUBB2A 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD IPO5 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD ANKMY2 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD PEX5 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD RPSA 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD FAM131B 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD RECQL4 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD ZNF790 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD DBN1 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD SULT1C2 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD ENO2 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD ANXA8 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD ANXA8L1 25348397 N/A physical interaction ComPPI
ACD TRIM16 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD PGM2 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD ZFP36L1 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD NUDCD2 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD SBDS 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD AFAP1L2 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD POF1B 25348397 N/A physical interaction ComPPI
ACD NTAQ1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CKB ACD 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
LGALSL ACD 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ADPRH ACD 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACD TERT 17237768 27898060 stimulant N/A OmniPath

Visualization










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