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GENE：ATP1B1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ATP1B1
FullNmae ATPase Na+/K+ transporting subunit beta 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:804
EnsembleID ENSG00000143153
Uniprot P05026

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ATP1B1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ATP1B1 GO:0001671,GO:0001671,GO:0001671,GO:0005515,GO:0005886,GO:0005886,GO:0005886,GO:0005890,GO:0005890,GO:0005890,GO:0005890,GO:0005890,GO:0005890,GO:0006874,GO:0006883,GO:0006883,GO:0006883,GO:0007155,GO:0010248,GO:0010248,GO:0010468,GO:0010882,GO:0014704,GO:0016020,GO:0016323,GO:0016324,GO:0016324,GO:0016328,GO:0019901,GO:0023026,GO:0030007,GO:0030007,GO:0030007,GO:0030315,GO:0030674,GO:0030674,GO:0031090,GO:0032781,GO:0035725,GO:0036126,GO:0036376,GO:0036376,GO:0036376,GO:0036376,GO:0042383,GO:0044861,GO:0045087,GO:0046034,GO:0046982,GO:0050821,GO:0050821,GO:0051117,GO:0055119,GO:0060048,GO:0070062,GO:0072659,GO:0086009,GO:0086013,GO:0086064,GO:0098655,GO:1901018,GO:1902600,GO:1903278,GO:1903278,GO:1903278,GO:1903281,GO:1903288,GO:1903288,GO:1903408,GO:1903408,GO:1903408,GO:1903561,GO:1990573,GO:1990573,GO:1990573

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ATP1B1 hsa:481 path:hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human)
ATP1B1 hsa:481 path:hsa04024 cAMP signaling pathway - Homo sapiens (human)
ATP1B1 hsa:481 path:hsa04260 Cardiac muscle contraction - Homo sapiens (human)
ATP1B1 hsa:481 path:hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human)
ATP1B1 hsa:481 path:hsa04911 Insulin secretion - Homo sapiens (human)
ATP1B1 hsa:481 path:hsa04918 Thyroid hormone synthesis - Homo sapiens (human)
ATP1B1 hsa:481 path:hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human)
ATP1B1 hsa:481 path:hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human)
ATP1B1 hsa:481 path:hsa04960 Aldosterone-regulated sodium reabsorption - Homo sapiens (human)
ATP1B1 hsa:481 path:hsa04961 Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human)
ATP1B1 hsa:481 path:hsa04964 Proximal tubule bicarbonate reclamation - Homo sapiens (human)
ATP1B1 hsa:481 path:hsa04970 Salivary secretion - Homo sapiens (human)
ATP1B1 hsa:481 path:hsa04971 Gastric acid secretion - Homo sapiens (human)
ATP1B1 hsa:481 path:hsa04972 Pancreatic secretion - Homo sapiens (human)
ATP1B1 hsa:481 path:hsa04973 Carbohydrate digestion and absorption - Homo sapiens (human)
ATP1B1 hsa:481 path:hsa04974 Protein digestion and absorption - Homo sapiens (human)
ATP1B1 hsa:481 path:hsa04976 Bile secretion - Homo sapiens (human)
ATP1B1 hsa:481 path:hsa04978 Mineral absorption - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGFR ATP1B1 16799092 23180781 physical association pull down InnateDB
ATP1B1 ELAVL1 19322201 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR ATP1B1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 ATP1B1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 ATP1B1 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ATP1B1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 ATP1B1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
NR3C1 ATP1B1 11216640 9694812 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
NR3C2 ATP1B1 11216640 9694812 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
SMARCA4 ATP1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ATP1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ATP1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ATP1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ATP1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ATP1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ATP1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ATP1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ATP1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PGR ATP1B1 22330642 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000B59A2 ATP1B1 23221637 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00000B59A2 ATP1B1 23221637 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
FXYD7 ATP1B1 12093728 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
EZH2 ATP1B1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SMAD2 ATP1B1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
PAXIP1 ATP1B1 25348397 N/A physical interaction ComPPI
CTSD ATP1B1 25348397 N/A physical interaction ComPPI
DLD ATP1B1 25348397 N/A physical interaction ComPPI
NTRK1 ATP1B1 25348397 N/A physical interaction ComPPI
CANX ATP1B1 25348397 N/A physical interaction ComPPI
HLA-DRB3 ATP1B1 25348397 N/A physical interaction ComPPI
VDAC1 ATP1B1 25348397 N/A physical interaction ComPPI
PDHA1 ATP1B1 25348397 N/A physical interaction ComPPI
RAB1A ATP1B1 25348397 N/A physical interaction ComPPI
USP4 ATP1B1 25348397 N/A physical interaction ComPPI
NEDD4L ATP1B1 25348397 N/A physical interaction ComPPI
HNRNPA2B1 ATP1B1 25348397 N/A physical interaction ComPPI
ATP1A1 ATP1B1 24234451 25012180 25348397 30021884 association,physical association anti bait coimmunoprecipitation,cross-linking study,physical interaction ComPPI,IntAct
FXYD1 ATP1B1 14525934 14597563 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ATP1B1 BACE1 14525934 15606899 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
ATP1B1 GCH1 14525934 16696853 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
ATP1B1 LRIF1 14525934 16169070 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
ATP1B1 EGFR 14525934 16799092 24234451 25348397 association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
ATP1B1 NDRG2 21771789 25348397 27898060 N/A physical interaction ComPPI,OmniPath
ATP1B1 HLA-DRA 25348397 N/A physical interaction ComPPI
ATP1B1 HLA-DRB1 25348397 N/A physical interaction ComPPI
ATP1B1 HLA-DRB4 25348397 N/A physical interaction ComPPI
ATP1B1 HLA-DRB5 25348397 N/A physical interaction ComPPI
ATP1B1 KMT2B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ATP1B1 TRMT2A 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ATP1B1 PSME1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ATP1B1 CRIP2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ATP1B1 ELAVL1 25348397 N/A physical interaction ComPPI
ATP1B1 BARD1 25348397 N/A physical interaction ComPPI
ATP1B1 BRCA1 25348397 N/A physical interaction ComPPI
ATP1B1 ATP4A 25348397 N/A physical interaction ComPPI
ATP1B1 CCDC8 25348397 N/A physical interaction ComPPI
ATP1B1 ACAA2 25348397 N/A physical interaction ComPPI
ATP1B1 ACAT1 25348397 N/A physical interaction ComPPI
ATP1B1 ACO2 25348397 N/A physical interaction ComPPI
ATP1B1 ATP6V1E1 25348397 N/A physical interaction ComPPI
ATP1B1 HADHA 25348397 N/A physical interaction ComPPI
ATP1B1 HADHB 25348397 N/A physical interaction ComPPI
ATP1B1 HNRNPA3 25348397 N/A physical interaction ComPPI
ATP1B1 HSD17B10 25348397 N/A physical interaction ComPPI
ATP1B1 LMAN1 25348397 N/A physical interaction ComPPI
ATP1B1 MRPS35 25348397 N/A physical interaction ComPPI
ATP1B1 RTN4 25348397 N/A physical interaction ComPPI
ATP1B1 SDHA 25348397 N/A physical interaction ComPPI
ATP1B1 ATP2A2 25348397 N/A physical interaction ComPPI
ATP1B1 ATP5PB 25348397 N/A physical interaction ComPPI
ATP1B1 ATP5MG 25348397 N/A physical interaction ComPPI
ATP1B1 COX6B1 25348397 N/A physical interaction ComPPI
ATP1B1 CPT2 25348397 N/A physical interaction ComPPI
ATP1B1 CYC1 25348397 N/A physical interaction ComPPI
ATP1B1 DLAT 25348397 N/A physical interaction ComPPI
ATP1B1 EIF4H 25348397 N/A physical interaction ComPPI
ATP1B1 FUBP1 25348397 N/A physical interaction ComPPI
ATP1B1 HSD17B12 25348397 N/A physical interaction ComPPI
ATP1B1 MTCH1 25348397 N/A physical interaction ComPPI
ATP1B1 MTCH2 25348397 N/A physical interaction ComPPI
ATP1B1 NDUFA12 25348397 N/A physical interaction ComPPI
ATP1B1 NDUFA2 25348397 N/A physical interaction ComPPI
ATP1B1 NDUFS1 25348397 N/A physical interaction ComPPI
ATP1B1 NDUFS3 25348397 N/A physical interaction ComPPI
ATP1B1 NDUFV1 25348397 N/A physical interaction ComPPI
ATP1B1 PSMD6 25348397 N/A physical interaction ComPPI
ATP1B1 RAB1C 25348397 N/A physical interaction ComPPI
ATP1B1 RAB1B 25348397 N/A physical interaction ComPPI
ATP1B1 RPL26 25348397 N/A physical interaction ComPPI
ATP1B1 RPS19 25348397 N/A physical interaction ComPPI
ATP1B1 TOMM40 25348397 N/A physical interaction ComPPI
ATP1B1 UQCRB 25348397 N/A physical interaction ComPPI
ATP1B1 UQCRFS1 25348397 N/A physical interaction ComPPI
ATP1B1 UQCRQ 25348397 N/A physical interaction ComPPI
ATP1B1 TSC22D2 25348397 N/A physical interaction ComPPI
ATP1B1 PDCD5 25348397 N/A physical interaction ComPPI
ATP1B1 TRIM25 25348397 N/A physical interaction ComPPI
ATP1B1 TARDBP 25348397 N/A physical interaction ComPPI
ATP1B1 RIF1 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
ATP1B1 NR3C1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
ATP1B1 MLC1 22328087 24234451 25348397 27898060 colocalization,physical association pull down,confocal microscopy ComPPI,IntAct,OmniPath
ATP1B1 SLC4A1 24234451 25012180 25348397 27898060 colocalization,association,physical association anti bait coimmunoprecipitation,classical fluorescence spectroscopy,two hybrid,pull down,enzyme linked immunosorbent assay,confocal microscopy ComPPI,IntAct,OmniPath
ATP1B1 KIRREL3 24234451 25348397 25902260 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,fluorescence microscopy ComPPI,IntAct
DDAH2 ATP1B1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ILVBL ATP1B1 25348397 N/A physical interaction ComPPI
ATP1B1 AGTR1 24234451 28298427 physical association anti tag coimmunoprecipitation,ubiquitin reconstruction IntAct
HTR2B ATP1B1 24234451 28298427 physical association ubiquitin reconstruction IntAct
EGFR ATP1B1 16799092 27898060 N/A N/A OmniPath

Visualization










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