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GENE：DNAJB1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DNAJB1
FullNmae DnaJ heat shock protein family (Hsp40) member B1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5270
EnsembleID ENSG00000132002
Uniprot P25685

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DNAJB1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DNAJB1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DNAJB1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DNAJB1 GO:0000122,GO:0000122,GO:0001671,GO:0001671,GO:0003714,GO:0003714,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005730,GO:0005737,GO:0005829,GO:0005829,GO:0005829,GO:0006986,GO:0014069,GO:0030544,GO:0030544,GO:0030900,GO:0032781,GO:0034605,GO:0043025,GO:0043197,GO:0044183,GO:0045296,GO:0051082,GO:0051082,GO:0051085,GO:0051085,GO:0051087,GO:0051117,GO:0061827,GO:0070062,GO:0090084,GO:0098978,GO:0140416,GO:1900034

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DNAJB1 hsa:3337 path:hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human)
DNAJB1 hsa:3337 path:hsa05164 Influenza A - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ISG15 DNAJB1 16009940 23180781 physical association unspecified method InnateDB
APP DNAJB1 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
AR DNAJB1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 DNAJB1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 DNAJB1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 DNAJB1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 DNAJB1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 DNAJB1 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 DNAJB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DNAJB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DNAJB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DNAJB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DNAJB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DNAJB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF DNAJB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 DNAJB1 N/A rna interference,inhibition experimental interaction detection miRSponge
URS0000338542 DNAJB1 18668040 22473208 25416803 mrna cleavage,inhibition experimental interaction detection,clip TarBase
URS00003380CC DNAJB1 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS0000065D58 DNAJB1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000016D2D4 DNAJB1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
MAPKAPK5 DNAJB1 22135298 phosphorylation N/A PhosphoSite
CFTR DNAJB1 25361965 interaction type N/A PTMCode2
DNAJB1 CFTR 25361965 interaction type N/A PTMCode2
HSPA8 DNAJB1 25361965 interaction type N/A PTMCode2
DNAJB1 HSPA8 25361965 interaction type N/A PTMCode2
STUB1 DNAJB1 25361965 interaction type N/A PTMCode2
DNAJB1 STUB1 25361965 interaction type N/A PTMCode2
DNAJB1 PTGES3 25361965 interaction type N/A PTMCode2
PTGES3 DNAJB1 25361965 interaction type N/A PTMCode2
DNAJB1 STIP1 25361965 interaction type N/A PTMCode2
STIP1 DNAJB1 25361965 interaction type N/A PTMCode2
DNAJB1 ANK2 25361965 interaction type N/A PTMCode2
ANK2 DNAJB1 25361965 interaction type N/A PTMCode2
DNAJB1 HSPA1A 25361965 interaction type N/A PTMCode2
HSPA1A DNAJB1 25361965 interaction type N/A PTMCode2
DNAJB1 DNAJC3 25361965 interaction type N/A PTMCode2
DNAJC3 DNAJB1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PRKAA2 DNAJB1 25348397 N/A physical interaction ComPPI
HSPA8 DNAJB1 25348397 N/A physical interaction ComPPI
ISG15 DNAJB1 25348397 N/A physical interaction ComPPI
EDF1 DNAJB1 25348397 N/A physical interaction ComPPI
BRMS1 DNAJB1 25348397 N/A in vivo ComPPI
VPS37B DNAJB1 25348397 N/A physical interaction ComPPI
PTPN18 DNAJB1 25348397 N/A physical interaction ComPPI
JUN DNAJB1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
HIF1A DNAJB1 25348397 N/A physical interaction ComPPI
SPP1 DNAJB1 25348397 N/A physical interaction ComPPI
CUL3 DNAJB1 25348397 N/A physical interaction ComPPI
TUBG1 DNAJB1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBC DNAJB1 25348397 N/A physical interaction ComPPI
NTRK1 DNAJB1 25348397 N/A physical interaction ComPPI
CDH1 DNAJB1 25348397 N/A physical interaction ComPPI
BAG1 DNAJB1 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
STIP1 DNAJB1 25348397 N/A physical interaction ComPPI
HSPA5 DNAJB1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPA1A DNAJB1 10593983 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
HSPA1B DNAJB1 25348397 N/A physical interaction,in vitro,in vivo ComPPI
PTGES3 DNAJB1 11809754 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
ZFP36 DNAJB1 25348397 N/A physical interaction ComPPI
DUSP16 DNAJB1 25348397 N/A physical interaction ComPPI
CFTR DNAJB1 17110338 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EWSR1 DNAJB1 25348397 N/A physical interaction ComPPI
ANG DNAJB1 24234451 25348397 28777577 association anti bait coimmunoprecipitation ComPPI,IntAct
DNAJC7 DNAJB1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HUWE1 DNAJB1 25348397 N/A physical interaction ComPPI
UBQLN2 DNAJB1 25348397 N/A physical interaction ComPPI
MDM2 DNAJB1 25348397 N/A physical interaction ComPPI
PSEN2 DNAJB1 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FANCC DNAJB1 11500375 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
DAG1 DNAJB1 25348397 N/A physical interaction ComPPI
TUBA1A DNAJB1 24234451 25348397 27291054 association pull down ComPPI,IntAct
HTT DNAJB1 25348397 N/A physical interaction ComPPI
HSPA4 DNAJB1 25348397 N/A physical interaction ComPPI
HSPH1 DNAJB1 25348397 N/A physical interaction ComPPI
HSPA9 DNAJB1 25348397 N/A physical interaction ComPPI
TSG101 DNAJB1 25348397 N/A physical interaction ComPPI
BAG4 DNAJB1 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GLB1 DNAJB1 14525934 25348397 27898060 8670798 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
PRKN DNAJB1 25348397 N/A physical interaction ComPPI
ETF1 DNAJB1 25348397 N/A physical interaction ComPPI
FOXA1 DNAJB1 25348397 N/A physical interaction ComPPI
CDC37 DNAJB1 21163940 24234451 25036637 25348397 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MAST1 DNAJB1 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SNCA DNAJB1 25348397 N/A physical interaction ComPPI
TERF1 DNAJB1 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
POT1 DNAJB1 25348397 N/A physical interaction ComPPI
SLC12A3 DNAJB1 25348397 N/A physical interaction ComPPI
ECSIT DNAJB1 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ESR1 DNAJB1 25348397 N/A physical interaction ComPPI
DNAJB1 ANK2 14525934 15075330 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
DNAJB1 STUB1 10330192 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
DNAJB1 NQO1 11821413 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
DNAJB1 HSF1 14525934 25348397 9499401 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
DNAJB1 SOD1 11457725 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
DNAJB1 FANCA 25348397 N/A physical interaction ComPPI
DNAJB1 GPR37 25348397 N/A physical interaction ComPPI
DNAJB1 OTUD4 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DNAJB1 ATG2A 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DNAJB1 WIPI2 20562859 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DNAJB1 TELO2 20801936 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
DNAJB1 CENPE 25348397 N/A physical interaction ComPPI
DNAJB1 AKT1 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DNAJB1 NRAS 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DNAJB1 PLEKHO1 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DNAJB1 PHLDA1 25348397 N/A physical interaction ComPPI
DNAJB1 APP 25348397 N/A physical interaction ComPPI
DNAJB1 CYP2C8 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DNAJB1 A2M 25348397 N/A physical interaction ComPPI
DNAJB1 BRCA1 25348397 N/A physical interaction ComPPI
DNAJB1 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
DNAJB1 ANKRD28 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
DNAJB1 ADSL 25348397 N/A physical interaction ComPPI
DNAJB1 RNASEH2B 25348397 N/A physical interaction ComPPI
DNAJB1 DPYSL2 25348397 N/A physical interaction ComPPI
DNAJB1 PDE12 25348397 N/A physical interaction ComPPI
DNAJB1 WDR4 25348397 N/A physical interaction ComPPI
DNAJB1 TP53 25348397 N/A physical interaction ComPPI
DNAJB1 BAG2 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DNAJB1 MLF2 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DNAJB1 NUDC 24234451 25036637 25348397 27173435 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DNAJB1 HSPA6 25348397 N/A physical interaction ComPPI
DNAJB1 FAF2 25348397 N/A physical interaction ComPPI
DNAJB1 DNAJB4 25348397 N/A physical interaction ComPPI
DNAJB1 LLGL2 25348397 N/A physical interaction ComPPI
DNAJB1 RPS6KB2 25348397 N/A physical interaction ComPPI
DNAJB1 AMBRA1 25348397 N/A physical interaction ComPPI
DNAJB1 GRPEL1 25348397 N/A physical interaction ComPPI
DNAJB1 HSPA4L 25348397 N/A physical interaction ComPPI
DNAJB1 HYOU1 25348397 N/A physical interaction ComPPI
DNAJB1 MED4 25348397 N/A physical interaction ComPPI
DNAJB1 MED20 25348397 N/A physical interaction ComPPI
DNAJB1 MAGED2 25348397 N/A physical interaction ComPPI
DNAJB1 TTLL12 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DNAJB1 DNAJB5 25348397 N/A physical interaction ComPPI
DNAJB1 DCAF6 25348397 N/A physical interaction ComPPI
DNAJB1 TBL1Y 25348397 N/A physical interaction ComPPI
DNAJB1 KCNC4 25348397 N/A physical interaction ComPPI
DNAJB1 DNAJA2 25348397 N/A physical interaction ComPPI
DNAJB1 MAP3K3 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
DNAJB1 IKBKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DNAJB1 GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DNAJB1 COA3 23260140 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DNAJB1 LLGL1 24234451 24366813 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DNAJB1 RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
DNAJB1 OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation ComPPI,IntAct
DNAJB1 TUBB3 24234451 25348397 27291054 association pull down ComPPI,IntAct
DNAJB1 KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
DNAJB1 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
XPO7 DNAJB1 25348397 N/A physical interaction ComPPI
PPID DNAJB1 25348397 N/A physical interaction ComPPI
ECPAS DNAJB1 25348397 N/A physical interaction ComPPI
ZNF16 DNAJB1 21874239 24234451 25348397 physical association two hybrid ComPPI,IntAct
DNAJB1 DNAJC3 14525934 9920933 N/A experimental interaction detection,two hybrid HPRD
METTL3 DNAJB1 24234451 29507755 association anti tag coimmunoprecipitation IntAct
BDKRB1 DNAJB1 24234451 28298427 physical association ubiquitin reconstruction IntAct
DNAJB1 HSF1 27898060 9499401 9869631 inhibition,stimulant N/A OmniPath
ISG15 DNAJB1 16009940 27898060 N/A N/A OmniPath
MAPKAPK5 DNAJB1 24309468 27898060 stimulant N/A OmniPath

Visualization










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