Gene Information gene info

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GENE：USP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol USP1
FullNmae ubiquitin specific peptidase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12607
EnsembleID ENSG00000162607
Uniprot O94782

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
USP1 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
USP1 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
USP1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
USP1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
USP1 GO:0001501,GO:0004197,GO:0004843,GO:0004843,GO:0004843,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005829,GO:0006281,GO:0006282,GO:0008233,GO:0009411,GO:0016579,GO:0016579,GO:0035520,GO:0046427,GO:1904333

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
USP1 hsa:7398 path:hsa03460 Fanconi anemia pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 USP1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 USP1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 USP1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 USP1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 USP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA USP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF USP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 USP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 USP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS USP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A USP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF USP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 USP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 USP1 N/A trascriptional regulation,stimulation inferred by curator TFlink
E2F2 USP1 N/A trascriptional regulation,stimulation inferred by curator TFlink
MYC USP1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 USP1 N/A 15806104 rna interference,inhibition experimental interaction detection miRSponge
URS00000ED600 USP1 15806104 20215506 25416803 mrna cleavage,inhibition array technology,experimental interaction detection TarBase
URS00000F31F4 USP1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 USP1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00001A405B USP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C04A2 USP1 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000D4AB5 USP1 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000001A7A USP1 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002C28B2 USP1 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000016E46F USP1 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003FA24D USP1 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000568FF8 USP1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000451A1 USP1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075D814 USP1 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 USP1 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004F859B USP1 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC USP1 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000021202F USP1 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002971AB USP1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000032835F USP1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C85B2 USP1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075AB0E USP1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD002 USP1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001C0099 USP1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 USP1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000355E82 USP1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000041FA2C USP1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK1 USP1 22135298 phosphorylation N/A PhosphoSite
WDR48 USP1 25361965 interaction type N/A PTMCode2
USP1 WDR48 25361965 interaction type N/A PTMCode2
FANCD2 USP1 25361965 interaction type N/A PTMCode2
USP1 FANCD2 25361965 interaction type N/A PTMCode2
USP1 PHLPP2 25361965 interaction type N/A PTMCode2
PHLPP2 USP1 25361965 interaction type N/A PTMCode2
USP4 USP1 25361965 interaction type N/A PTMCode2
USP1 USP4 25361965 interaction type N/A PTMCode2
RPS27A USP1 25361965 interaction type N/A PTMCode2
USP1 RPS27A 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KRT4 USP1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SGTB USP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PCNA USP1 25348397 N/A physical interaction ComPPI
CALML3 USP1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRAF6 USP1 25348397 N/A physical interaction ComPPI
KPNA1 USP1 19615732 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FZR1 USP1 25348397 N/A physical interaction ComPPI
FLG USP1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JUP USP1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBC USP1 25348397 N/A physical interaction ComPPI
STAT2 USP1 25348397 N/A physical interaction ComPPI
BAG6 USP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FANCD2 USP1 14525934 15694335 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RAD51AP1 USP1 25348397 N/A physical interaction ComPPI
USP4 USP1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UNC45A USP1 25348397 N/A physical interaction ComPPI
SYNCRIP USP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPB1 USP1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBE2A USP1 25348397 N/A physical interaction ComPPI
UBE2K USP1 25348397 N/A physical interaction ComPPI
CSE1L USP1 25348397 N/A physical interaction ComPPI
PKP1 USP1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CALML5 USP1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ID2 USP1 25348397 N/A physical interaction ComPPI
SOCS6 USP1 25348397 N/A physical interaction ComPPI
AKT1 USP1 25348397 N/A physical interaction ComPPI
CAPNS1 USP1 25348397 N/A physical interaction ComPPI
SORT1 USP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DTX3 USP1 25348397 N/A physical interaction ComPPI
KATNA1 USP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EZR USP1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
MYH9 USP1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DSG1 USP1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WDR5 USP1 25348397 N/A physical interaction ComPPI
USP1 DSC1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP1 KRT17 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP1 LGALS7 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP1 LYZ 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP1 PHLPP2 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP1 PHLPP1 19615732 22426999 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
USP1 WDR48 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP1 TAGLN2 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP1 ALDH16A1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP1 ATAD5 25348397 N/A physical interaction ComPPI
USP1 VPS26A 25348397 N/A physical interaction ComPPI
USP1 VPS36 25348397 N/A physical interaction ComPPI
USP1 PHF7 25348397 N/A physical interaction ComPPI
USP1 TRIM46 25348397 N/A physical interaction ComPPI
USP1 ANAPC1 25348397 N/A physical interaction ComPPI
USP1 TOR1AIP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP1 CERK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP1 USP43 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP1 RSRP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP1 LRRC15 25348397 N/A physical interaction ComPPI
USP1 ANXA2P2 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
UBB USP1 14525934 15694335 N/A experimental interaction detection HPRD
USP1 PCNA 16531995 21768287 22987070 22989887 27898060 inhibition N/A OmniPath
USP1 FANCD2 15694335 16633336 18082604 27898060 inhibition,stimulant N/A OmniPath
CDK1 USP1 23116119 27898060 N/A N/A OmniPath
USP1 FANCI 17488615 27898060 inhibition,stimulant N/A OmniPath

Visualization










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