Gene Information gene info

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GENE：EIF1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EIF1
FullNmae eukaryotic translation initiation factor 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3249
EnsembleID ENSG00000173812
Uniprot P41567

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EIF1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EIF1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EIF1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EIF1 GO:0003723,GO:0003723,GO:0003743,GO:0003743,GO:0003743,GO:0005515,GO:0005634,GO:0005737,GO:0006413,GO:0006446,GO:0008135,GO:0009048,GO:0016282,GO:0016282,GO:0033290,GO:0043024,GO:0043024,GO:0043614

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EIF1 IL2RA 23180781 8896456 physical association electrophoretic mobility supershift assay InnateDB
APP EIF1 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 EIF1 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA EIF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EIF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 EIF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A EIF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF EIF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000065D58 EIF1 18668040 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition experimental interaction detection,clip TarBase
URS00000AA464 EIF1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 EIF1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004AC389 EIF1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016D2D4 EIF1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000079D48 EIF1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000011A030 EIF1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000C85B2 EIF1 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 EIF1 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F EIF1 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 EIF1 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000393C7 EIF1 21572407 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 EIF1 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F EIF1 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000040FA88 EIF1 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 EIF1 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001E3523 EIF1 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000419B5A EIF1 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000585553 EIF1 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000BE495 EIF1 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF EIF1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000037E170 EIF1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000383DF4 EIF1 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
EIF3J EIF1 25361965 interaction type N/A PTMCode2
EIF1 EIF3J 25361965 interaction type N/A PTMCode2
EIF1AX EIF1 25361965 interaction type N/A PTMCode2
EIF1 EIF1AX 25361965 interaction type N/A PTMCode2
EIF3B EIF1 25361965 interaction type N/A PTMCode2
EIF1 EIF3B 25361965 interaction type N/A PTMCode2
EIF2S1 EIF1 25361965 interaction type N/A PTMCode2
EIF1 EIF2S1 25361965 interaction type N/A PTMCode2
EIF3C EIF1 25361965 interaction type N/A PTMCode2
EIF1 EIF3C 25361965 interaction type N/A PTMCode2
EIF5A EIF1 25361965 interaction type N/A PTMCode2
EIF1 EIF5A 25361965 interaction type N/A PTMCode2
EIF2S2 EIF1 25361965 interaction type N/A PTMCode2
EIF1 EIF2S2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
EIF3G EIF1 25348397 N/A physical interaction ComPPI
EIF5 EIF1 25348397 N/A physical interaction ComPPI
DHX9 EIF1 25348397 N/A physical interaction ComPPI
MAPK6 EIF1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EIF3C EIF1 23623729 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
RASA1 EIF1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EIF2D EIF1 25348397 N/A physical interaction ComPPI
EIF3A EIF1 23623729 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
OLFM2 EIF1 14525934 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
APP EIF1 25348397 N/A physical interaction ComPPI
EPB41 EIF1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
EIF1 UPF2 11073994 14525934 N/A experimental interaction detection,two hybrid HPRD
EIF1 NECAB3 11018020 12411506 12861028 15377664 15485912 17974565 22718758 27898060 9660829 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00008C0394 EIF1 27087310 direct interaction,inhibition N/A NPInter

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