GENE:HJURP
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | HJURP |
| FullNmae | Holliday junction recognition protein |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:25444 |
| EnsembleID | ENSG00000123485 |
| Uniprot | Q8NCD3 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| HJURP | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| HJURP | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| HJURP | GO:0000775,GO:0000775,GO:0000776,GO:0003677,GO:0005515,GO:0005654,GO:0005654,GO:0005730,GO:0005829,GO:0007059,GO:0034080,GO:0034080,GO:0042393,GO:0042393,GO:0042393,GO:0042802,GO:0043254,GO:0051101 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | HJURP | 17531812 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ETS1 | HJURP | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | HJURP | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | HJURP | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | HJURP | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | HJURP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | HJURP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | HJURP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | HJURP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000F31F4 | HJURP | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000B59A2 | HJURP | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00002B7450 | HJURP | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000355E82 | HJURP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D814 | HJURP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006372A | HJURP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C0099 | HJURP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000032835F | HJURP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003FBC84 | HJURP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F2EB0 | HJURP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AKT1 | HJURP | 22135298 | phosphorylation | N/A | PhosphoSite |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| OIP5 | HJURP | 25348397 | N/A | physical interaction | ComPPI |
| MIS18A | HJURP | 25348397 | N/A | physical interaction | ComPPI |
| NPM1 | HJURP | 25348397 | N/A | physical interaction,physical interaction,tandem affinity purification | ComPPI |
| MCM2 | HJURP | 24234451 25348397 26167883 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| H4C1 | HJURP | 19410544 21478274 24234451 25348397 | association,physical association | pull down,physical interaction | ComPPI,IntAct |
| RUVBL1 | HJURP | 25348397 | N/A | physical interaction,physical interaction,tandem affinity purification | ComPPI |
| RBBP4 | HJURP | 24234451 25348397 27705803 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| HDAC11 | HJURP | 23752268 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| IMMT | HJURP | 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
| FBXW11 | HJURP | 25348397 | N/A | physical interaction | ComPPI |
| SHMT2 | HJURP | 25348397 | N/A | physical interaction | ComPPI |
| RUVBL2 | HJURP | 25348397 | N/A | physical interaction,physical interaction,tandem affinity purification | ComPPI |
| CENPA | HJURP | 16622419 19410544 19410545 20080577 21478274 22406139 24234451 25348397 25727006 26496610 27898060 | colocalization,association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,cosedimentation through density gradient,molecular sieving,pull down,x-ray crystallography,physical interaction,confocal microscopy,tandem affinity purification | ComPPI,IntAct,OmniPath |
| HJURP | STT3A | 16169070 24234451 25348397 | physical association | two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
| HJURP | RBBP7 | 25348397 | N/A | physical interaction,physical interaction,tandem affinity purification | ComPPI |
| HJURP | MOV10 | 25348397 | N/A | physical interaction | ComPPI |
| HJURP | NXF1 | 25348397 | N/A | physical interaction | ComPPI |
| HJURP | LRRC46 | 25348397 | N/A | physical interaction | ComPPI |
| HJURP | TUBA3C | 25348397 | N/A | physical interaction | ComPPI |
| HJURP | DUS1L | 25348397 | N/A | physical interaction | ComPPI |
| PASK | HJURP | 25348397 | N/A | physical interaction | ComPPI |
| HJURP | HJURP | 23771058 24234451 | physical association | anti tag coimmunoprecipitation,molecular sieving,protein complementation assay,pull down | IntAct |
| AKT1 | HJURP | 17256767 18691976 27898060 | N/A | N/A | OmniPath |
