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GENE：ARFGAP3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ARFGAP3
FullNmae ADP ribosylation factor GTPase activating protein 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:661
EnsembleID ENSG00000242247
Uniprot Q9NP61

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ARFGAP3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ARFGAP3 GO:0000139,GO:0005096,GO:0005096,GO:0005515,GO:0005794,GO:0005829,GO:0005829,GO:0006886,GO:0009306,GO:0016020,GO:0016192,GO:0046872,GO:0048205

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ARFGAP3 hsa:26286 path:hsa04144 Endocytosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR ARFGAP3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 ARFGAP3 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 ARFGAP3 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 ARFGAP3 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ARFGAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ARFGAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ARFGAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ARFGAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ARFGAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ARFGAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000DDD35 ARFGAP3 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
EGLN3 ARFGAP3 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
SMAD2 ARFGAP3 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PLEC ARFGAP3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAPK6 ARFGAP3 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
XPO1 ARFGAP3 25348397 N/A physical interaction ComPPI
ZDHHC17 ARFGAP3 24234451 24705354 25348397 physical association two hybrid,physical interaction,two hybrid array,luminescence based mammalian interactome mapping ComPPI,IntAct
HTT ARFGAP3 23275563 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
CXCL8 ARFGAP3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DYNLT1 ARFGAP3 25348397 N/A physical interaction ComPPI
ARFGAP1 ARFGAP3 25348397 N/A physical interaction ComPPI
TGOLN2 ARFGAP3 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
BET1 ARFGAP3 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RTN4IP1 ARFGAP3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ARF1 ARFGAP3 25348397 N/A physical interaction ComPPI
ARFGAP3 APP 25348397 N/A physical interaction ComPPI
ARFGAP3 CD14 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ARFGAP3 ADI1 25348397 N/A physical interaction ComPPI
ARFGAP3 NTAQ1 25348397 N/A physical interaction ComPPI
ARFGAP3 CCDC102B 25348397 N/A physical interaction ComPPI
ARFGAP3 LIME1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM26 ARFGAP3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct

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