Gene Information gene info

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GENE：ATRIP

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ATRIP
FullNmae ATR interacting protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:33499
EnsembleID ENSG00000164053
Uniprot Q8WXE1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ATRIP mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ATRIP autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ATRIP GO:0000077,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0006139,GO:0006281,GO:0070310,GO:0070530,GO:2000779

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ATRIP hsa:84126 path:hsa03460 Fanconi anemia pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ATR ATRIP 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611 26192618 interaction type N/A ACSN
ATRIP CHEK1 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611 26192618 interaction type N/A ACSN
ATRIP CLSPN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611 26192618 interaction type N/A ACSN
PCNA ATRIP 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611 26192618 interaction type N/A ACSN
ATRIP TIPIN 11877377 12086603 12766152 12875843 14988723 15136767 15175241 15459660 15798197 16713580 16805667 16880517 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 20051983 26192618 interaction type N/A ACSN
ATRIP RAD17 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
ATRIP TOPBP1 11877377 12766152 15459660 15485915 15798197 16530042 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17582221 18677104 19282663 19622404 19793801 26192618 interaction type N/A ACSN
MLH1 ATRIP 12556884 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 17581638 18157157 18406444 18543256 19151707 19847258 20478261 26192618 interaction type N/A ACSN
PMS2 ATRIP 12556884 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 17581638 18157157 18406444 18543256 19151707 19847258 20478261 26192618 interaction type N/A ACSN
MSH2 ATRIP 12556884 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 18157157 18406444 18543256 19151707 19473888 19595721 19596235 19596236 19847258 20478261 26192618 interaction type N/A ACSN
MSH6 ATRIP 12556884 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 18157157 18406444 18543256 19151707 19473888 19595721 19596235 19596236 19847258 20478261 26192618 interaction type N/A ACSN
RPA1 ATRIP 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
RPA2 ATRIP 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
RPA3 ATRIP 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
ATRIP ORC1 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
ATRIP ORC2 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
ATRIP ORC3 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
ATRIP ORC4 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
ATRIP ORC5 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
ATRIP ORC6 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
ATRIP MCM2 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
ATRIP MCM3 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
ATRIP MCM4 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
ATRIP MCM5 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
ATRIP MCM6 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
ATRIP MCM7 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
ATRIP CDT1 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
ATRIP CDC6 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
ATRIP CDC45 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
ATRIP RAD1 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
ATRIP HUS1 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN

Source Target Pmid Interactiontype Methods Database
AR ATRIP 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 ATRIP 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 ATRIP 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 ATRIP 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 ATRIP 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ATRIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ATRIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ATRIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ATRIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ATRIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
CDK2 ATRIP 22135298 phosphorylation N/A PhosphoSite
ATR ATRIP 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
RPA1 ATRIP 25361965 interaction type N/A PTMCode2
ATRIP RPA1 25361965 interaction type N/A PTMCode2
ATM ATRIP 25361965 interaction type N/A PTMCode2
ATRIP ATM 25361965 interaction type N/A PTMCode2
CDC6 ATRIP 25361965 interaction type N/A PTMCode2
ATRIP CDC6 25361965 interaction type N/A PTMCode2
MCM7 ATRIP 25361965 interaction type N/A PTMCode2
ATRIP MCM7 25361965 interaction type N/A PTMCode2
ATRIP ATR 25361965 interaction type N/A PTMCode2
ATRIP HNRNPUL1 25361965 interaction type N/A PTMCode2
HNRNPUL1 ATRIP 25361965 interaction type N/A PTMCode2
ATRIP BRCA1 25361965 interaction type N/A PTMCode2
BRCA1 ATRIP 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MOS ATRIP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 ATRIP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FAM156A ATRIP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TP53BP1 ATRIP 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
MCM2 ATRIP 25348397 N/A physical interaction ComPPI
ATR ATRIP 11721054 14525934 17686975 19889979 20616048 24234451 25348397 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,molecular sieving,physical interaction,ion exchange chromatography ComPPI,HPRD,IntAct
PRKDC ATRIP 14525934 15758953 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
RPA1 ATRIP 12791985 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
CDC6 ATRIP 25348397 N/A physical interaction ComPPI
ATM ATRIP 14525934 15758953 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
RPA2 ATRIP 25348397 N/A physical interaction ComPPI
RPA3 ATRIP 25348397 N/A physical interaction ComPPI
RRM2B ATRIP 19015526 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CHEK1 ATRIP 20639859 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
CD70 ATRIP 25348397 N/A physical interaction ComPPI
MID2 ATRIP 25348397 N/A physical interaction ComPPI
GDA ATRIP 25348397 N/A physical interaction ComPPI
HNRNPUL1 ATRIP 25348397 N/A physical interaction ComPPI
CDK9 ATRIP 20930849 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK16 ATRIP 25348397 N/A physical interaction ComPPI
PEX14 ATRIP 25348397 N/A physical interaction ComPPI
NBN ATRIP 14525934 15758953 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
BRCA1 ATRIP 24234451 25348397 29656893 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TIMELESS ATRIP 15798197 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LNX1 ATRIP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
IFT20 ATRIP 14525934 16189514 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FANCL ATRIP 25348397 N/A physical interaction ComPPI
MCM7 ATRIP 14525934 15210935 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
C1ORF94 ATRIP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RIBC2 ATRIP 16189514 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PNKD ATRIP 25348397 N/A physical interaction ComPPI
TASOR2 ATRIP 25348397 N/A physical interaction ComPPI
CDC23 ATRIP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MUL1 ATRIP 25348397 N/A physical interaction ComPPI
MSH2 ATRIP 14525934 14657349 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
CINP ATRIP 19889979 24234451 25348397 25416956 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SCG2 ATRIP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FAAP24 ATRIP 25348397 N/A physical interaction ComPPI
KIR3DL2 ATRIP 25348397 N/A physical interaction ComPPI
HERC2 ATRIP 25348397 N/A physical interaction ComPPI
ST6GAL1 ATRIP 25348397 N/A physical interaction ComPPI
TOPBP1 ATRIP 20871591 24234451 25348397 colocalization physical interaction,fluorescence microscopy ComPPI,IntAct
POLR1C ATRIP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HERC2P3 ATRIP 25348397 N/A physical interaction ComPPI
TELO2 ATRIP 25348397 N/A physical interaction ComPPI
IKBKG ATRIP 18583959 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ATRIP CEP164 25348397 N/A physical interaction ComPPI
ATRIP CCDC28B 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ATRIP METTL21A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ATRIP NPEPL1 25348397 N/A physical interaction ComPPI
ATRIP FZD10 25348397 N/A physical interaction ComPPI
ATRIP FAAP100 25348397 N/A physical interaction ComPPI
HSCB ATRIP 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
MX2 ATRIP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MKI67 ATRIP 24234451 26949251 association anti tag coimmunoprecipitation IntAct
CDK2 ATRIP 17638878 27898060 stimulant N/A OmniPath
ATR ATRIP 11721054 14657349 14724280 15210935 15451423 15758953 17384638 17686975 18162465 18283122 18344416 19097996 19889979 20616048 20847938 21285353 27898060 stimulant N/A OmniPath
RPA1 ATRIP 12791985 15743907 17339343 21859891 24332808 27898060 stimulant N/A OmniPath
RPA2 ATRIP 20068082 27898060 stimulant N/A OmniPath
ATRIP BRCA1 14578343 17616665 24073851 27898060 stimulant N/A OmniPath
ATRIP TOPBP1 18769153 20871591 27898060 stimulant N/A OmniPath
TOPBP1 ATRIP 18769153 20068082 20871591 27898060 stimulant N/A OmniPath
XRCC5 ATRIP 18285803 27898060 stimulant N/A OmniPath

Visualization










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