Gene Information gene info

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GENE：BAG5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol BAG5
FullNmae BAG cochaperone 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:941
EnsembleID ENSG00000166170
Uniprot Q9UL15

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
BAG5 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BAG5 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BAG5 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
BAG5 GO:0000774,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0005829,GO:0005829,GO:0006457,GO:0007030,GO:0010977,GO:0016020,GO:0016020,GO:0016234,GO:0019901,GO:0030314,GO:0031397,GO:0031397,GO:0031397,GO:0031397,GO:0031625,GO:0031625,GO:0032435,GO:0048471,GO:0050821,GO:0050821,GO:0051087,GO:0051087,GO:0051438,GO:0051444,GO:0061084,GO:0090083,GO:0090083,GO:1902176

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 BAG5 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 BAG5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 BAG5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 BAG5 18668040 22473208 25416803 mrna cleavage,inhibition experimental interaction detection,clip TarBase
URS0000324096 BAG5 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00003D5391 BAG5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE BAG5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003E5ECC BAG5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000BD6DC BAG5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000009EA8F BAG5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005FDE70 BAG5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000024A59E BAG5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000035D2F9 BAG5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 BAG5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000007340 BAG5 25416803 27571744 mrna cleavage,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
BAG5 HSPA1B 25361965 interaction type N/A PTMCode2
HSPA1B BAG5 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
DES BAG5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSPA8 BAG5 24234451 24510904 25348397 29568061 association anti tag coimmunoprecipitation,pull down,proximity-dependent biotin identification ComPPI,IntAct
CIAO2B BAG5 25348397 N/A physical interaction ComPPI
KASH5 BAG5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PTPN18 BAG5 25348397 N/A physical interaction ComPPI
CUL3 BAG5 25348397 N/A physical interaction ComPPI
TUBG1 BAG5 24234451 25348397 29568061 association pull down ComPPI,IntAct
HSPA1A BAG5 24234451 24510904 25348397 association,physical association anti tag coimmunoprecipitation,molecular sieving,pull down,x-ray crystallography,physical interaction ComPPI,IntAct
HSPA1B BAG5 25348397 N/A anti tag coimmunoprecipitation,molecular sieving,pull down,x-ray crystallography,physical interaction ComPPI
KSR2 BAG5 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
DUSP16 BAG5 24234451 25348397 28330616 association pull down ComPPI,IntAct
SOX2 BAG5 25348397 N/A physical interaction ComPPI
EGFR BAG5 25348397 N/A physical interaction ComPPI
TUBA1A BAG5 24234451 25348397 27291054 29568061 association pull down ComPPI,IntAct
POLR3E BAG5 25348397 N/A physical interaction ComPPI
HSPA4 BAG5 25348397 N/A physical interaction ComPPI
MMS19 BAG5 25348397 N/A physical interaction ComPPI
BANP BAG5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PSMD2 BAG5 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
EFEMP1 BAG5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKN BAG5 25348397 N/A physical interaction ComPPI
SNCA BAG5 25348397 N/A physical interaction ComPPI
GAK BAG5 24234451 24510904 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
P2RX6 BAG5 25348397 N/A physical interaction ComPPI
TRIM27 BAG5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MAD2L1 BAG5 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
STUB1 BAG5 25348397 N/A physical interaction ComPPI
MAP3K3 BAG5 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
MAD1L1 BAG5 24234451 25036637 25348397 25416956 association,physical association anti tag coimmunoprecipitation,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
UIMC1 BAG5 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CIRBP BAG5 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FBXW11 BAG5 25348397 N/A physical interaction ComPPI
DLG5 BAG5 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR2F BAG5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THAP1 BAG5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ABL2 BAG5 25348397 N/A physical interaction ComPPI
NDRG2 BAG5 25348397 N/A physical interaction ComPPI
FAM118B BAG5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BAG5 OTUD4 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BAG5 FBXO25 25348397 N/A physical interaction ComPPI
BAG5 LRRK2 24234451 24510904 24947832 25348397 association,physical association anti tag coimmunoprecipitation,protein array,pull down,physical interaction ComPPI,IntAct
BAG5 LATS2 25348397 N/A physical interaction ComPPI
BAG5 TP53 25348397 N/A physical interaction ComPPI
BAG5 DNAJC13 25348397 N/A physical interaction ComPPI
BAG5 ALDH3B1 25348397 N/A physical interaction ComPPI
BAG5 FRMD5 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BAG5 LLGL2 25348397 N/A physical interaction ComPPI
BAG5 AMBRA1 25348397 N/A physical interaction ComPPI
BAG5 GBA2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BAG5 AGO3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BAG5 SBF2 25348397 N/A physical interaction ComPPI
BAG5 KCNC4 25348397 N/A physical interaction ComPPI
BAG5 KLHL10 25348397 N/A physical interaction ComPPI
BAG5 ABHD15 25348397 N/A physical interaction ComPPI
BAG5 MAP3K1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
BAG5 SLX4 19596235 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BAG5 LLGL1 24234451 24366813 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BAG5 LRRK1 24234451 24510904 24947832 25348397 association anti tag coimmunoprecipitation,protein array ComPPI,IntAct
BAG5 HSF2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
BAG5 RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
BAG5 TUBB3 24234451 25348397 27291054 association pull down ComPPI,IntAct
BAG5 CDCA7L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BAG5 KRTAP5-4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BAG5 GOLGA6A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BAG5 LCE1D 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PINK1 BAG5 25348397 N/A physical interaction ComPPI
HSCB BAG5 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
BAG5 BAG5 14525934 15603737 N/A experimental interaction detection HPRD
METTL3 BAG5 24234451 29507755 association anti tag coimmunoprecipitation IntAct

Visualization










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