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GENE：ELL

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ELL
FullNmae elongation factor for RNA polymerase II
LocusType gene with protein product
Status Approved
HGNC_id HGNC:23114
EnsembleID ENSG00000105656
Uniprot P55199

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ELL autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ELL GO:0000791,GO:0000987,GO:0001701,GO:0005515,GO:0005654,GO:0005654,GO:0005829,GO:0006368,GO:0008023,GO:0008023,GO:0015030,GO:0016604,GO:0016607,GO:0019902,GO:0032786,GO:0032968,GO:0032968,GO:0035363,GO:0042795,GO:0042795,GO:0042796,GO:0045945

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ELL hsa:8178 path:hsa03250 Viral life cycle - HIV-1 - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 ELL 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 ELL 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A ELL 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 ELL 20953172 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ELL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ELL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ELL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ELL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ELL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 ELL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ELL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ELL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ELL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR ELL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ELL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EAF1 ELL 16006523 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004E008F ELL 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D ELL 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001B341F ELL 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000029D793 ELL 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000FB5B8 ELL 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000192A75 ELL 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000065FDF ELL 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002578DA ELL 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000054A671 ELL 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000076E54 ELL 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002B0B46 ELL 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000028D811 ELL 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000572E11 ELL 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MTOR ELL 22135298 phosphorylation N/A PhosphoSite
ELL TP53 25361965 interaction type N/A PTMCode2
TP53 ELL 25361965 interaction type N/A PTMCode2
ELL EAF2 25361965 interaction type N/A PTMCode2
EAF2 ELL 25361965 interaction type N/A PTMCode2
ELL EAF1 25361965 interaction type N/A PTMCode2
EAF1 ELL 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
DYNLL1 ELL 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TFPT ELL 14525934 17395368 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,fluorescence microscopy,in vivo ComPPI,HPRD,IntAct
SNRPA1 ELL 25348397 N/A physical interaction ComPPI
MCM2 ELL 19819239 24234451 25348397 N/A pull down,physical interaction ComPPI,IntAct
UBC ELL 25348397 N/A physical interaction ComPPI
PPP1CA ELL 19389623 24234451 25348397 physical association far western blotting,pull down ComPPI,IntAct
HNRNPU ELL 10490622 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CTR9 ELL 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HUWE1 ELL 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ZHX1 ELL 25348397 N/A physical interaction ComPPI
CDK7 ELL 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
POLR2A ELL 14525934 25348397 27898060 9268387 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
SIRT2 ELL 25348397 N/A physical interaction ComPPI
ELL EAF2 12446457 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ELL EAF1 11418481 14525934 21729782 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
ELL SNF8 10419521 14525934 19819239 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,competition binding,in vitro ComPPI,HPRD,IntAct,OmniPath
ELL TP53 10358050 14525934 25348397 27898060 8016121 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD,OmniPath
ELL USPL1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELL MLLT3 21729782 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELL MLLT1 25348397 N/A physical interaction ComPPI
ELL KMT2A 25348397 N/A physical interaction ComPPI
ELL MED26 21729782 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELL ICE2 21729782 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELL ICE1 21729782 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELL AFF4 21729782 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELL CDK9 21729782 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELL ELL3 25348397 N/A physical interaction ComPPI
ELL DENND2D 25348397 N/A physical interaction ComPPI
ELL OFD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELL NCBP2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELL FGFR1OP2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELL SIKE1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELL INTS14 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELL ASPM 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELL CAMKV 25348397 N/A physical interaction ComPPI
ELL PIP4K2A 25348397 N/A physical interaction ComPPI
ELL TRIM25 25348397 N/A physical interaction ComPPI
SGG ELL 25348397 N/A anti tag coimmunoprecipitation ComPPI
MTS ELL 14605208 24234451 25348397 physical association two hybrid ComPPI,IntAct
TSH ELL 14605208 24234451 25348397 physical association two hybrid ComPPI,IntAct
EAF2 ELL 12446457 16006523 27898060 stimulant N/A OmniPath
EAF1 ELL 11418481 16006523 21729782 26186194 27898060 stimulant N/A OmniPath

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