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GENE：HBP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HBP1
FullNmae HMG-box transcription factor 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:23200
EnsembleID ENSG00000105856
Uniprot O60381

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HBP1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HBP1 GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0003723,GO:0005515,GO:0005634,GO:0005654,GO:0006357,GO:0016055,GO:0016607,GO:0051726

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
HBP1 EGR1 19374776 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 HBP1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 HBP1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 HBP1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 HBP1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 HBP1 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC HBP1 12747840 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 HBP1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 HBP1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 HBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA HBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 HBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS HBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A HBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF HBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RB1 HBP1 16966377 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 HBP1 20584899 rna interference,inhibition experimental interaction detection miRSponge
URS00002075FA HBP1 20505989 rna interference,inhibition experimental interaction detection miRSponge
URS0000076995 HBP1 23541945 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000237AF9 HBP1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000338542 HBP1 20584899 24675724 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00002075FA HBP1 20505989 22473208 23592263 23622248 25416803 mrna cleavage,inhibition experimental interaction detection,clip,clash TarBase
URS0000076995 HBP1 23541945 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS0000042E1F HBP1 22473208 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 HBP1 22473208 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 HBP1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 HBP1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 HBP1 22473208 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC HBP1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB HBP1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 HBP1 22473208 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 HBP1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE HBP1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 HBP1 22473208 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A HBP1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC HBP1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B HBP1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 HBP1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 HBP1 20371350 21572407 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 HBP1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 HBP1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 HBP1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 HBP1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000032D69B HBP1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000195F5B HBP1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C HBP1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002E177F HBP1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 HBP1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002F8148 HBP1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000122ED0 HBP1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001FFA8C HBP1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDA4 HBP1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004D84DB HBP1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000235862 HBP1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000025EABA HBP1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B HBP1 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MAPK14 HBP1 22135298 phosphorylation N/A PhosphoSite
PIM1 HBP1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
PRKAR2B HBP1 25348397 N/A physical interaction ComPPI
ZNF212 HBP1 18255255 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SMAD1 HBP1 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
CD2AP HBP1 18654987 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RB1 HBP1 14525934 23859194 24234451 25348397 27898060 9178770 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
CREBBP HBP1 25348397 N/A physical interaction ComPPI
EP300 HBP1 25348397 N/A physical interaction ComPPI
TCF7L2 HBP1 25348397 N/A physical interaction ComPPI
RBL2 HBP1 14525934 25348397 9178770 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
SIN3A HBP1 14525934 15235594 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
CASP8 HBP1 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MYC HBP1 25348397 N/A physical interaction ComPPI
EWSR1 HBP1 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
HBP1 SAP30 14525934 15235594 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
HBP1 KIFBP 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
HBP1 HDAC1 14525934 15235594 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
HBP1 ANKRD2 25348397 N/A physical interaction ComPPI
HBP1 TMEM37 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HBP1 FBXW11 25348397 N/A physical interaction ComPPI
HBP1 RMND5A 25348397 N/A physical interaction ComPPI
HBP1 ESR1 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HBP1 RB1CC1 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TCF4 HBP1 11500377 14525934 27898060 N/A experimental interaction detection HPRD,OmniPath
HBP1 MYC 20008325 27898060 inhibition N/A OmniPath
MAPK14 HBP1 14612426 27898060 stimulant N/A OmniPath
MAPK11 HBP1 14612426 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B8290 HBP1 27087310 direct interaction,inhibition N/A NPInter

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