Gene Information gene info

  1. Home

GENE：MCCC2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MCCC2
FullNmae methylcrotonyl-CoA carboxylase subunit 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6937
EnsembleID ENSG00000131844
Uniprot Q9HCC0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MCCC2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MCCC2 GO:0002169,GO:0002169,GO:0002169,GO:0004485,GO:0004485,GO:0004485,GO:0005515,GO:0005524,GO:0005739,GO:0005739,GO:0005739,GO:0005759,GO:0005759,GO:0005829,GO:0006552,GO:0006552,GO:0006552,GO:0009083,GO:0015936,GO:1905202,GO:1905202

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MCCC2 hsa:64087 path:hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human)
MCCC2 hsa:64087 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ADRB2 MCCC2 23180781 23798571 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR MCCC2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 MCCC2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 MCCC2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 MCCC2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CTCF MCCC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MCCC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MCCC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MCCC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MCCC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC MCCC2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 MCCC2 21512034 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00004E008F MCCC2 23622248 23824327 25416803 27292025 mrna cleavage,inhibition clip,clash TarBase
URS00003AFAD1 MCCC2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000078918 MCCC2 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00005CCD18 MCCC2 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000486E0B MCCC2 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003AD2AA MCCC2 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000029EBD MCCC2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000153377 MCCC2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000F7766 MCCC2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003D4175 MCCC2 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MCCC2 EPS15 25361965 interaction type N/A PTMCode2
EPS15 MCCC2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
LGALS3 MCCC2 25348397 N/A physical interaction ComPPI
UBASH3B MCCC2 19380743 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
FASTKD3 MCCC2 20869947 24234451 25348397 association tandem affinity purification ComPPI,IntAct
RECK MCCC2 25348397 N/A physical interaction ComPPI
GABARAPL2 MCCC2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
KEAP1 MCCC2 25348397 N/A physical interaction ComPPI
JUN MCCC2 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
INPPL1 MCCC2 19380743 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CUL3 MCCC2 25348397 N/A physical interaction ComPPI
NTRK1 MCCC2 25348397 N/A physical interaction ComPPI
WWP2 MCCC2 25348397 N/A physical interaction ComPPI
HNRNPL MCCC2 25348397 N/A physical interaction ComPPI
C1QBP MCCC2 25348397 N/A physical interaction ComPPI
HUWE1 MCCC2 25348397 N/A physical interaction ComPPI
EPS15 MCCC2 19380743 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
ADRB2 MCCC2 25348397 N/A physical interaction ComPPI
MAP1LC3A MCCC2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PTEN MCCC2 25348397 N/A physical interaction ComPPI
STK4 MCCC2 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
PRKN MCCC2 25348397 N/A physical interaction ComPPI
HDAC11 MCCC2 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NFKB1 MCCC2 24234451 25348397 25609649 association tandem affinity purification ComPPI,IntAct
DYNC1H1 MCCC2 25348397 N/A physical interaction ComPPI
TRIM25 MCCC2 25348397 N/A physical interaction ComPPI
PMPCA MCCC2 25348397 N/A physical interaction ComPPI
TERF1 MCCC2 25348397 N/A physical interaction ComPPI
ECSIT MCCC2 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TERF2 MCCC2 25348397 N/A physical interaction ComPPI
PMPCB MCCC2 25348397 N/A physical interaction ComPPI
HSPD1 MCCC2 25348397 N/A physical interaction ComPPI
ATP5F1C MCCC2 25348397 N/A physical interaction ComPPI
IFIT1 MCCC2 21642987 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ECH1 MCCC2 25348397 N/A physical interaction ComPPI
POU5F1 MCCC2 25348397 N/A physical interaction ComPPI
UQCRFS1 MCCC2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
HMGCL MCCC2 25348397 N/A physical interaction ComPPI
ATAD3B MCCC2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
OTUB1 MCCC2 24234451 25348397 26752685 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPB2 MCCC2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
PPP2R2B MCCC2 25348397 N/A anti tag coimmunoprecipitation ComPPI
NANOGP8 MCCC2 25348397 N/A physical interaction ComPPI
NANOG MCCC2 25348397 N/A physical interaction ComPPI
MCCC2 MRPL58 20186120 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MCCC2 MCCC1 25348397 N/A physical interaction ComPPI
MCCC2 CYB5B 25348397 N/A physical interaction ComPPI
MCCC2 ATP5F1E 25348397 N/A physical interaction ComPPI
MCCC2 SIRT4 24234451 25348397 25525879 association anti tag coimmunoprecipitation ComPPI,IntAct
MCCC2 NDUFA4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
MCCC2 NDUFAB1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
MCCC2 LYRM7 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
L1TD1 MCCC2 24234451 25702638 association anti bait coimmunoprecipitation IntAct

Visualization










  Return