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GENE：PTPRN2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PTPRN2
FullNmae protein tyrosine phosphatase receptor type N2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9677
EnsembleID ENSG00000155093
Uniprot Q92932

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PTPRN2 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PTPRN2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PTPRN2 GO:0005001,GO:0005886,GO:0006470,GO:0006629,GO:0007269,GO:0030141,GO:0030667,GO:0030672,GO:0035773,GO:0035773,GO:0043235,GO:0045202,GO:0051046,GO:0101003

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PTPRN2 hsa:5799 path:hsa04940 Type I diabetes mellitus - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGR1 PTPRN2 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
GATA2 PTPRN2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A PTPRN2 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
YBX1 PTPRN2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C PTPRN2 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
NR1I2 PTPRN2 19129222 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 PTPRN2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PTPRN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PTPRN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PTPRN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PTPRN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PTPRN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 PTPRN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PTPRN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PTPRN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PTPRN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
IGF1R PTPRN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PTPRN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PTPRN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PTPRN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR PTPRN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 PTPRN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PTPRN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 PTPRN2 18185580 rna interference,inhibition array technology,experimental interaction detection,miRNA interference luciferase reporter assay miRSponge
URS0000237AF9 PTPRN2 18185580 25416803 mrna cleavage,inhibition array technology,array technology,experimental interaction detection,miRNA interference luciferase reporter assay TarBase
URS000039607D PTPRN2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D PTPRN2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 PTPRN2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 PTPRN2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004407DC PTPRN2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDA4 PTPRN2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000100748 PTPRN2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000148B91 PTPRN2 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NUP155 PTPRN2 25348397 N/A physical interaction ComPPI
GRB2 PTPRN2 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
HGS PTPRN2 25348397 N/A physical interaction ComPPI
HSPA5 PTPRN2 25348397 N/A physical interaction ComPPI
STAM2 PTPRN2 25348397 N/A physical interaction ComPPI
HNRNPL PTPRN2 25348397 N/A physical interaction ComPPI
GOLGA4 PTPRN2 25348397 N/A physical interaction ComPPI
HID1 PTPRN2 25348397 N/A physical interaction ComPPI
UBQLN4 PTPRN2 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
NR3C1 PTPRN2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
STAM PTPRN2 25348397 N/A physical interaction ComPPI
PTPRN PTPRN2 25348397 N/A physical interaction ComPPI
SPTBN4 PTPRN2 11086001 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
PTPRN2 CKAP5 12421765 14525934 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PTPRN2 INTS11 25348397 N/A physical interaction ComPPI
PTPRN2 MON2 25348397 N/A physical interaction ComPPI
PTPRN2 MOSPD2 25348397 N/A physical interaction ComPPI
PTPRN2 SEC61A1 25348397 N/A physical interaction ComPPI
PTPRN2 SORT1 25348397 N/A physical interaction ComPPI
PTPRN2 TELO2 25348397 N/A physical interaction ComPPI
PTPRN2 SNX19 25348397 N/A physical interaction ComPPI
PTPRN2 KRT17 25348397 N/A physical interaction ComPPI
PTPRN2 KRT16 25348397 N/A physical interaction ComPPI
PTPRN2 STIM1 25348397 N/A physical interaction ComPPI
PTPRN2 CLCC1 25348397 N/A physical interaction ComPPI
PTPRN2 KRT14 25348397 N/A physical interaction ComPPI
PTPRN2 ANKLE2 25348397 N/A physical interaction ComPPI
PTPRN2 FAM20C 22582013 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
PTPRN2 PTPRN2 15978577 24234451 association tox-r dimerization assay IntAct

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