Gene Information gene info

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GENE：ZYX

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ZYX
FullNmae zyxin
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13200
EnsembleID ENSG00000159840
Uniprot Q15942

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ZYX autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ZYX GO:0001725,GO:0001725,GO:0003723,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0005886,GO:0005912,GO:0005925,GO:0005925,GO:0005925,GO:0007160,GO:0007179,GO:0007179,GO:0007229,GO:0007229,GO:0007267,GO:0015629,GO:0043149,GO:0045335,GO:0046872,GO:0071346

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ZYX hsa:7791 path:hsa04510 Focal adhesion - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
YWHAG ZYX 17572661 23180781 physical association anti tag coimmunoprecipitation InnateDB
IL7R ZYX 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 ZYX 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 ZYX 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C ZYX 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ZYX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ZYX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ZYX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ZYX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ZYX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR ZYX 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004BCD9C ZYX 23175429 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr TarBase
URS000016FF9C ZYX 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000BE495 ZYX 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000007A060 ZYX 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 ZYX 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000170CF4 ZYX 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CDK2 ZYX 22135298 phosphorylation N/A PhosphoSite
AKT1 ZYX 22135298 phosphorylation N/A PhosphoSite
VASP ZYX 25361965 interaction type N/A PTMCode2
ZYX VASP 25361965 interaction type N/A PTMCode2
ZHX1 ZYX 25361965 interaction type N/A PTMCode2
ZYX ZHX1 25361965 interaction type N/A PTMCode2
ZYX LASP1 25361965 interaction type N/A PTMCode2
LASP1 ZYX 25361965 interaction type N/A PTMCode2
ZYX ENAH 25361965 interaction type N/A PTMCode2
ENAH ZYX 25361965 interaction type N/A PTMCode2
ZYX NEDD9 25361965 interaction type N/A PTMCode2
NEDD9 ZYX 25361965 interaction type N/A PTMCode2
RPH3AL ZYX 25361965 interaction type N/A PTMCode2
ZYX RPH3AL 25361965 interaction type N/A PTMCode2
LATS1 ZYX 25361965 interaction type N/A PTMCode2
ZYX LATS1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
LIN7A ZYX 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
UBE2I ZYX 20936779 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
FHL3 ZYX 25348397 N/A physical interaction ComPPI
DHX15 ZYX 25348397 N/A physical interaction ComPPI
QRICH1 ZYX 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SEC23B ZYX 25348397 N/A physical interaction ComPPI
PPIB ZYX 11423549 24234451 25348397 physical association two hybrid ComPPI,IntAct
ZNRD2 ZYX 25348397 N/A physical interaction ComPPI
VASP ZYX 10882740 14525934 24234451 25348397 7644520 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
NPM1 ZYX 25348397 N/A physical interaction ComPPI
VIM ZYX 25348397 N/A physical interaction ComPPI
ATXN1 ZYX 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZNF512B ZYX 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KEAP1 ZYX 25348397 N/A physical interaction ComPPI
UBL7 ZYX 25348397 N/A physical interaction ComPPI
H4C1 ZYX 25348397 N/A physical interaction ComPPI
VAV1 ZYX 14525934 25348397 8622875 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
ZYX ACTN1 10224105 11423549 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
ZYX LASP1 22665060 24234451 25348397 association,physical association pull down,physical interaction,in vitro,proximity ligation assay ComPPI,IntAct
ZYX RPH3AL 14525934 25348397 27898060 9367993 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD,OmniPath
ZYX VAV3 14525934 25348397 8622875 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
ZYX LATS1 10831611 14525934 24234451 25348397 colocalization,physical association two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,imaging technique,in vitro,in vivo ComPPI,HPRD,IntAct
ZYX NEBL 11423549 14525934 15004028 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
ZYX NEDD9 11782456 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
ZYX ENAH 10801818 14525934 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
ZYX BSPRY 10978534 11423549 14525934 24234451 25348397 27898060 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct,OmniPath
ZYX TES 12695497 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ZYX HIPK3 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZYX ZHX1 25348397 N/A physical interaction ComPPI
ZYX BCAR1 11782456 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ZYX WNK1 25348397 N/A physical interaction ComPPI
ZYX SREBF2 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
ZYX RABEPK 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ZYX RGS2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ZYX ARRB1 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ZYX NEDD8 25348397 N/A physical interaction ComPPI
ZYX VHL 25348397 N/A physical interaction ComPPI
ZYX UBE2V2 25348397 N/A physical interaction ComPPI
ZYX TPM1 25348397 N/A physical interaction ComPPI
ZYX TTLL12 25348397 N/A physical interaction ComPPI
ZYX SEC22B 25348397 N/A physical interaction ComPPI
ZYX TPM4 25348397 N/A physical interaction ComPPI
ZYX AHCYL1 25348397 N/A physical interaction ComPPI
ZYX UBE2B 25348397 N/A physical interaction ComPPI
ZYX USP9X 25348397 N/A physical interaction ComPPI
ZYX UBXN7 25348397 N/A physical interaction ComPPI
ZYX UCHL3 25348397 N/A physical interaction ComPPI
ZYX UBE2V1 25348397 N/A physical interaction ComPPI
ZYX FSCN1 25348397 N/A physical interaction ComPPI
ZYX ZC3H7B 25348397 N/A physical interaction ComPPI
ZYX CNN2 25348397 N/A physical interaction ComPPI
ZYX TOMM34 25348397 N/A physical interaction ComPPI
ZYX RCN1 25348397 N/A physical interaction ComPPI
ZYX ACTA2 25348397 N/A physical interaction ComPPI
ZYX ZPR1 25348397 N/A physical interaction ComPPI
ZYX UFC1 25348397 N/A physical interaction ComPPI
ZYX FERMT2 25348397 N/A physical interaction ComPPI
ZYX FN1 11423549 19738201 24234451 25348397 association,physical association two hybrid,cross-linking study,physical interaction ComPPI,IntAct
ZYX VCAM1 19738201 22623428 24234451 25348397 association cross-linking study,pull down,physical interaction ComPPI,IntAct
ZYX NIBAN2 25348397 N/A physical interaction ComPPI
ZYX GARS1 25348397 N/A physical interaction ComPPI
ZYX NUDC 25348397 N/A physical interaction ComPPI
ZYX PAPOLA 25348397 N/A physical interaction ComPPI
ZYX PXN 25348397 N/A physical interaction ComPPI
ZYX SEC24C 25348397 N/A physical interaction ComPPI
ZYX CAND1 25348397 N/A physical interaction ComPPI
ZYX CORO1B 25348397 N/A physical interaction ComPPI
ZYX GART 25348397 N/A physical interaction ComPPI
ZYX PUF60 25348397 N/A physical interaction ComPPI
ZYX TARS1 25348397 N/A physical interaction ComPPI
ZYX UGP2 25348397 N/A physical interaction ComPPI
ZYX PDLIM5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ZYX PHF21A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ZYX YPEL3 25348397 N/A physical interaction ComPPI
ZYX RTN4IP1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ZYX OPRM1 23840749 24234451 25348397 physical association two hybrid,pull down,physical interaction ComPPI,IntAct
ZYX TUFT1 25348397 N/A physical interaction ComPPI
ZYX CD2AP 25348397 N/A physical interaction ComPPI
ZYX AHSA1 25348397 N/A physical interaction ComPPI
ZYX DPH5 25348397 N/A physical interaction ComPPI
ZYX HSPB1 25348397 N/A physical interaction ComPPI
ZYX RAD23B 25348397 N/A physical interaction ComPPI
ZYX MED4 25348397 N/A physical interaction ComPPI
ZYX XPO1 25348397 N/A physical interaction ComPPI
ZYX CNTROB 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ZYX U2AF2 25348397 N/A physical interaction ComPPI
ZYX SIRT1 25348397 N/A physical interaction ComPPI
ZYX SIAH2 25348397 N/A physical interaction ComPPI
ZYX LATS2 25348397 N/A physical interaction ComPPI
ZYX ATOH1 25348397 N/A physical interaction ComPPI
ZYX CDH1 25348397 N/A physical interaction ComPPI
ZYX PPP3CB 25348397 N/A physical interaction ComPPI
ZYX CCAR1 25348397 N/A physical interaction ComPPI
ZYX TANC2 25348397 N/A physical interaction ComPPI
ZYX FKBP15 25348397 N/A physical interaction ComPPI
ZYX SECISBP2L 25348397 N/A physical interaction ComPPI
ZYX ZFR 25348397 N/A physical interaction ComPPI
ZYX MAS1 25348397 N/A physical interaction ComPPI
ZYX TBC1D10B 25348397 N/A physical interaction ComPPI
ZYX GMPPA 25348397 N/A physical interaction ComPPI
ZYX EVL 25348397 N/A physical interaction ComPPI
ZYX UBE2N 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ZYX CYLD 25348397 N/A physical interaction ComPPI
ZYX FOXA1 25348397 N/A physical interaction ComPPI
ZYX TRIM25 25348397 N/A physical interaction ComPPI
ZYX YAP1 25348397 N/A physical interaction ComPPI
ZYX SLX4 19596235 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
ZYX ACTN2 11423549 24234451 25348397 physical association two hybrid ComPPI,IntAct
ZYX FBLN2 11423549 24234451 25348397 physical association two hybrid ComPPI,IntAct
ZYX PPIA 11423549 24234451 25348397 physical association two hybrid ComPPI,IntAct
ZYX TRIP6 11423549 24234451 25348397 physical association two hybrid ComPPI,IntAct
ZYX SNX5 11423549 24234451 25348397 physical association two hybrid ComPPI,IntAct
ZYX GRIP1 11423549 24234451 25348397 physical association two hybrid ComPPI,IntAct
ZYX PPARG 11423549 24234451 25348397 physical association two hybrid ComPPI,IntAct
ZYX TJP2 22665060 24234451 25348397 association far western blotting ComPPI,IntAct
ZYX TFAP2C 24234451 24835590 25348397 physical association two hybrid ComPPI,IntAct
ZYX JUN 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
ZYX LAP3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IMP3 ZYX 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
APEH ZYX 25348397 N/A physical interaction ComPPI
ATP6V1B2 ZYX 25348397 N/A physical interaction ComPPI
ZNF384 ZYX 14525934 16510139 N/A experimental interaction detection,two hybrid HPRD
HNRNPA0 ZYX 24234451 30021884 physical association cross-linking study IntAct
IL7R ZYX 20167604 27898060 N/A N/A OmniPath
AKT1 ZYX 17572661 27898060 inhibition N/A OmniPath

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