Gene Information gene info

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GENE：EFEMP2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EFEMP2
FullNmae EGF containing fibulin extracellular matrix protein 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3219
EnsembleID ENSG00000172638
Uniprot O95967

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EFEMP2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EFEMP2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EFEMP2 GO:0001527,GO:0005201,GO:0005509,GO:0005515,GO:0005576,GO:0005604,GO:0008201,GO:0031012,GO:0031012,GO:0035904,GO:0042803,GO:0048251,GO:0048251,GO:0060414,GO:0062023,GO:0070062,GO:0071953,GO:0071953,GO:0097084,GO:1903561,GO:1904026,GO:1904028,GO:1904706,GO:1904831,GO:1905609

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IL16 EFEMP2 16189514 23180781 physical association two hybrid InnateDB
EFEMP2 RHOXF2 16189514 23180781 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
AR EFEMP2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 EFEMP2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
NR1I2 EFEMP2 19129222 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 EFEMP2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
EGR1 EFEMP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF EFEMP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000134ADC EFEMP2 21611196 \N rna interference,inhibition experimental interaction detection,western blot,miRNA interference luciferase reporter assay miRSponge
URS0000134ADC EFEMP2 16822819 18927107 21611196 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr miR2Disease,TarBase
URS000075ADAC EFEMP2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000170CF4 EFEMP2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF EFEMP2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004AD450 EFEMP2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000247AC6 EFEMP2 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ZNF581 EFEMP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RBPMS EFEMP2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NOS3 EFEMP2 21163940 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ZNF774 EFEMP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FAM90A1 EFEMP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FAM110A EFEMP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
THAP7 EFEMP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STK16 EFEMP2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HOXA1 EFEMP2 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
RHOXF2 EFEMP2 16189514 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid prey pooling approach ComPPI,IntAct
CATSPER1 EFEMP2 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
CDPF1 EFEMP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
OTX1 EFEMP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRTAP10-8 EFEMP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LCE3C EFEMP2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LCE3E EFEMP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LCE2D EFEMP2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SGTA EFEMP2 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GLRX3 EFEMP2 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EFEMP2 SGTB 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EFEMP2 MEOX2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EFEMP2 AQP1 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EFEMP2 COL8A1 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EFEMP2 CCND3 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EFEMP2 BAG6 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EFEMP2 IL16 25348397 N/A two hybrid,physical interaction ComPPI
EFEMP2 UBQLN1 16189514 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 APEX2 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EFEMP2 HHEX 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EFEMP2 PLSCR4 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EFEMP2 FAM124B 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EFEMP2 PLSCR1 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EFEMP2 CCNK 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EFEMP2 PIDD1 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EFEMP2 RIBC2 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EFEMP2 ZNF638 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EFEMP2 TCAF1 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EFEMP2 LINGO1 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EFEMP2 ZNF426 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EFEMP2 RHPN1 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EFEMP2 GFI1B 16713569 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EFEMP2 UBQLN4 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
EFEMP2 RERE 16713569 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EFEMP2 ELN 19570982 24234451 25348397 physical association surface plasmon resonance,enzyme linked immunosorbent assay,surface plasmon resonance array ComPPI,IntAct
EFEMP2 LOX 19570982 19855011 24234451 25348397 physical association anti tag coimmunoprecipitation,surface plasmon resonance,physical interaction,enzyme linked immunosorbent assay,solid phase assay,surface plasmon resonance array ComPPI,IntAct
EFEMP2 FBLN5 19570982 24234451 25348397 physical association surface plasmon resonance,enzyme linked immunosorbent assay,surface plasmon resonance array ComPPI,IntAct
EFEMP2 FBN1 19570982 24234451 25348397 physical association surface plasmon resonance,enzyme linked immunosorbent assay,surface plasmon resonance array ComPPI,IntAct
EFEMP2 FAM107A 16189514 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EFEMP2 TP53 25348397 N/A physical interaction ComPPI
EFEMP2 ATXN7 21078624 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EFEMP2 CACNA1A 21078624 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EFEMP2 NEDD4L 25348397 N/A physical interaction ComPPI
EFEMP2 ATN1 16713569 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EFEMP2 DGCR6 25348397 N/A physical interaction ComPPI
EFEMP2 PTGER3 25348397 N/A physical interaction ComPPI
EFEMP2 CREB5 25348397 N/A physical interaction ComPPI
EFEMP2 HDAC4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EFEMP2 NUFIP2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EFEMP2 CCDC33 25348397 N/A physical interaction ComPPI
EFEMP2 C5ORF24 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EFEMP2 TFAP2C 24234451 24835590 25348397 physical association two hybrid ComPPI,IntAct
EFEMP2 FAM74A4 24234451 25348397 25416956 physical association two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EFEMP2 AMMECR1 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EFEMP2 IGFBP6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 MRPL12 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 MDFI 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 CXCL5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 TRIB3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 SLC16A5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 ZNF57 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 RNF138 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 KRTAP3-2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 KRTAP26-1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 RBP3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 ZNF558 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 CYSRT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 SPATA8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 KRTAP13-3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 ZNF699 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 TRIM42 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 DOK7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 ZNF587 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 KRTAP11-1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 RAB40B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 INCA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 KRTAP12-2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 SPRY4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 LCE3D 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 RBAK 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 RUSC1-AS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 KLF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 CLPP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 LCE1C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 LCE1A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 LCE3A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 DMBX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 LCE1E 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 LCE2C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 PRR32 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 ZNF345 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 ZNF768 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 AP1M1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 HPCAL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 SPACA9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 CNNM3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 HSPBP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 USP21 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 HSD3B7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 ITGB5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 PITX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 FBXW5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 P2RX7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 TLX3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 LNX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 HSPA12B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 PRPF31 24234451 25348397 25910212 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
EFEMP2 ZNF837 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 C3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 PROP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 LBX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ARRDC3 EFEMP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATXN1 EFEMP2 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ZNF263 EFEMP2 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EFEMP2 EFEMP2 19570982 24234451 N/A light scattering IntAct
EFEMP2 ELN 19570982 27898060 stimulant N/A OmniPath
LOX EFEMP2 19570982 19855011 27898060 stimulant N/A OmniPath
FBN1 EFEMP2 19570982 27898060 inhibition N/A OmniPath

Visualization










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