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GENE：RPS27L

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RPS27L
FullNmae ribosomal protein S27 like
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18476
EnsembleID ENSG00000185088
Uniprot Q71UM5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RPS27L parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RPS27L mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RPS27L apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RPS27L apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
RPS27L GO:0000028,GO:0003723,GO:0003723,GO:0003735,GO:0005515,GO:0005634,GO:0006412,GO:0006919,GO:0006978,GO:0008494,GO:0008656,GO:0022627,GO:0031571,GO:0042771,GO:0045727,GO:0046872

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RPS27L hsa:51065 path:hsa03010 Ribosome - Homo sapiens (human)
RPS27L hsa:51065 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR RPS27L 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 RPS27L 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 RPS27L 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP73 RPS27L 21245298 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 RPS27L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RPS27L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 RPS27L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RPS27L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RPS27L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 RPS27L 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005651EE RPS27L 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CDK2 RPS27L 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
MAD2L2 RPS27L 24234451 25348397 29656893 association anti tag coimmunoprecipitation ComPPI,IntAct
CTDSP2 RPS27L 25348397 N/A physical interaction ComPPI
RPL9 RPS27L 25348397 N/A physical interaction ComPPI
RPS7 RPS27L 24234451 25348397 30021884 physical association cross-linking study,physical interaction ComPPI,IntAct
NPM1 RPS27L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPS28 RPS27L 25348397 N/A physical interaction ComPPI
RPL37A RPS27L 25348397 N/A physical interaction ComPPI
RPL11 RPS27L 25348397 N/A physical interaction ComPPI
MCM2 RPS27L 25348397 N/A physical interaction ComPPI
RACK1 RPS27L 25348397 N/A physical interaction ComPPI
RPL10A RPS27L 25348397 N/A physical interaction ComPPI
JUN RPS27L 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
ZMYND8 RPS27L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPS3A RPS27L 25348397 N/A physical interaction ComPPI
MYC RPS27L 21150319 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NFKBIA RPS27L 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PA2G4 RPS27L 25348397 N/A physical interaction ComPPI
MAPK6 RPS27L 24234451 25348397 26972000 29426014 association anti tag coimmunoprecipitation ComPPI,IntAct
EIF2S1 RPS27L 25348397 N/A physical interaction ComPPI
RANBP9 RPS27L 25348397 N/A physical interaction ComPPI
RPS6 RPS27L 25348397 N/A physical interaction ComPPI
RPS25 RPS27L 25348397 N/A physical interaction ComPPI
RPL12 RPS27L 25348397 N/A physical interaction ComPPI
RPS13 RPS27L 25348397 N/A physical interaction ComPPI
RPL4 RPS27L 25348397 N/A physical interaction ComPPI
RPLP2 RPS27L 25348397 N/A physical interaction ComPPI
SNRPD3 RPS27L 25348397 N/A physical interaction ComPPI
MDM2 RPS27L 21170087 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,confocal microscopy ComPPI,IntAct
SYNCRIP RPS27L 25348397 N/A physical interaction ComPPI
RPL7A RPS27L 25348397 N/A physical interaction ComPPI
TUBA1A RPS27L 24234451 25348397 29568061 association pull down ComPPI,IntAct
VHL RPS27L 25348397 N/A physical interaction ComPPI
TNFRSF1B RPS27L 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RPL7 RPS27L 25348397 N/A physical interaction ComPPI
CDC37 RPS27L 25348397 N/A physical interaction ComPPI
RPL5 RPS27L 25348397 N/A physical interaction ComPPI
IARS1 RPS27L 25348397 N/A physical interaction ComPPI
ESR2 RPS27L 21182203 24234451 25348397 association affinity chromatography technology,cosedimentation through density gradient ComPPI,IntAct
MAP3K3 RPS27L 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RPL6 RPS27L 25348397 N/A physical interaction ComPPI
ESRRB RPS27L 25348397 N/A physical interaction ComPPI
RPL23A RPS27L 25348397 N/A physical interaction ComPPI
RPL13 RPS27L 25348397 N/A physical interaction ComPPI
RPL23 RPS27L 25348397 N/A physical interaction ComPPI
RPS20 RPS27L 25348397 N/A physical interaction ComPPI
LNX1 RPS27L 25348397 N/A physical interaction ComPPI
RPL14 RPS27L 25348397 N/A physical interaction ComPPI
AGO2 RPS27L 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
AGO1 RPS27L 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RPSA RPS27L 25348397 N/A physical interaction ComPPI
RPL24 RPS27L 25348397 N/A physical interaction ComPPI
ILF3 RPS27L 25348397 N/A physical interaction ComPPI
RPS2 RPS27L 25348397 N/A physical interaction ComPPI
RPS15A RPS27L 25348397 N/A physical interaction ComPPI
RPL31 RPS27L 25348397 N/A physical interaction ComPPI
RPS11 RPS27L 25348397 N/A physical interaction ComPPI
FAU RPS27L 25348397 N/A physical interaction ComPPI
RPS4X RPS27L 25348397 N/A physical interaction ComPPI
RPL21 RPS27L 25348397 N/A physical interaction ComPPI
RPL35A RPS27L 25348397 N/A physical interaction ComPPI
RPL22 RPS27L 25348397 N/A physical interaction ComPPI
RPL17 RPS27L 25348397 N/A physical interaction ComPPI
RPS3 RPS27L 25348397 N/A physical interaction ComPPI
RPS27 RPS27L 25348397 N/A physical interaction ComPPI
RPL15 RPS27L 25348397 N/A physical interaction ComPPI
RPS16 RPS27L 25348397 N/A physical interaction ComPPI
UVRAG RPS27L 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MAP3K1 RPS27L 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
ASB4 RPS27L 25348397 N/A physical interaction ComPPI
ERBB3 RPS27L 25348397 N/A physical interaction ComPPI
G3BP1 RPS27L 25348397 N/A physical interaction ComPPI
RPL18 RPS27L 25348397 N/A physical interaction ComPPI
IKBKG RPS27L 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
E2F3 RPS27L 22157815 24234451 25348397 association pull down ComPPI,IntAct
FAU RPS27L 25348397 N/A physical interaction ComPPI
RPS21 RPS27L 25348397 N/A physical interaction ComPPI
RIPK4 RPS27L 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
RPS12 RPS27L 25348397 N/A physical interaction ComPPI
PPP2R2B RPS27L 19156129 24234451 25348397 association pull down ComPPI,IntAct
RPS27L RPL27A 25348397 N/A physical interaction ComPPI
RPS27L RPS8 25348397 N/A physical interaction ComPPI
RPS27L RPL19 25348397 N/A physical interaction ComPPI
RPS27L RPS23 25348397 N/A physical interaction ComPPI
RPS27L RPS24 25348397 N/A physical interaction ComPPI
RPS27L PYM1 25348397 N/A physical interaction ComPPI
RPS27L UNK 25348397 N/A physical interaction ComPPI
RPS27L ZNF746 25348397 N/A physical interaction ComPPI
RPS27L SHLD3 24234451 25348397 29656893 association anti tag coimmunoprecipitation ComPPI,IntAct
MKI67 RPS27L 24234451 26949251 association anti tag coimmunoprecipitation IntAct
TP53 RPS27L 18431400 27898060 stimulant N/A OmniPath

Visualization










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