Gene Information gene info

GENE:GCHFR

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GCHFR
FullNmae GTP cyclohydrolase I feedback regulator
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4194
EnsembleID ENSG00000137880
Uniprot P30047

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GCHFR autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GCHFR GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0006809,GO:0009890,GO:0030425,GO:0031965,GO:0042133,GO:0042470,GO:0043105,GO:0044549

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CEBPA GCHFR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GCHFR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 GCHFR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GCHFR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GCHFR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 GCHFR N/A trascriptional regulation,stimulation inferred by curator TFlink
E2F2 GCHFR N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
GCHFR GCH1 25361965 interaction type N/A PTMCode2
GCH1 GCHFR 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SPINK2 GCHFR 25348397 N/A physical interaction ComPPI
EIF4G1 GCHFR 25348397 N/A physical interaction ComPPI
MYC GCHFR 25348397 N/A physical interaction ComPPI
FXYD1 GCHFR 25348397 N/A physical interaction ComPPI
GCHFR GCH1 14525934 16696853 24234451 25348397 8702680 physical association two hybrid,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
GCHFR MOV10 25348397 N/A physical interaction ComPPI
GCHFR CAMKK2 25348397 N/A physical interaction ComPPI
GCHFR CBFB 25348397 N/A physical interaction ComPPI
GCHFR PUSL1 25348397 N/A physical interaction ComPPI
GCHFR NEBL 25348397 N/A physical interaction ComPPI
GCHFR OBSL1 25348397 N/A physical interaction ComPPI
GCHFR DOCK11 25348397 N/A physical interaction ComPPI
GCHFR HBS1L 25348397 N/A physical interaction ComPPI
GCHFR IRF2BP2 25348397 N/A physical interaction ComPPI
GCHFR GCHFR 14525934 9092499 N/A experimental interaction detection HPRD
GCHFR GCH1 11361142 16696853 27898060 8702680 9092499 9685352 inhibition N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B7D6B GCHFR 27087310 direct interaction,inhibition N/A NPInter

Visualization