GENE:HERPUD1
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | HERPUD1 |
FullNmae | homocysteine inducible ER protein with ubiquitin like domain 1 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:13744 |
EnsembleID | ENSG00000051108 |
Uniprot | Q15011 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
HERPUD1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
HERPUD1 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
HERPUD1 | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
HERPUD1 | GO:0003674,GO:0005515,GO:0005783,GO:0005789,GO:0005789,GO:0005789,GO:0006511,GO:0006986,GO:0016020,GO:0030433,GO:0030968,GO:0030970,GO:0031396,GO:0032469,GO:0032469,GO:0034976,GO:0044322,GO:0044325,GO:0044325,GO:0045047,GO:1902236,GO:1902236,GO:1903069,GO:1903071,GO:1903071,GO:1990037,GO:1990756,GO:2001243 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
HERPUD1 | hsa:9709 | path:hsa04141 | Protein processing in endoplasmic reticulum - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | HERPUD1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
ETS1 | HERPUD1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
FOXA1 | HERPUD1 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
MYC | HERPUD1 | 12695333 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
FOXP3 | HERPUD1 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
PRDM14 | HERPUD1 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
SMARCA4 | HERPUD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | HERPUD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | HERPUD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | HERPUD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | HERPUD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | HERPUD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | HERPUD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | HERPUD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SPI1 | HERPUD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000508C13 | HERPUD1 | N/A 15685193 | rna interference,inhibition | array technology | miRSponge |
URS0000508C13 | HERPUD1 | 15685193 25416803 | mrna cleavage,inhibition | array technology,array technology,experimental interaction detection | TarBase |
URS0000237AF9 | HERPUD1 | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00000ED600 | HERPUD1 | 20215506 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS000003ABC4 | HERPUD1 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00003D5391 | HERPUD1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00000DDD35 | HERPUD1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00000AD002 | HERPUD1 | 23592263 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000037E170 | HERPUD1 | 23592263 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075C4B1 | HERPUD1 | 23592263 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000007F792 | HERPUD1 | 23592263 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000122ED0 | HERPUD1 | 23592263 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000032EF64 | HERPUD1 | 23592263 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000237CBD | HERPUD1 | 23592263 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000029979D | HERPUD1 | 23592263 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000000B1C9 | HERPUD1 | 23592263 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000A07C1 | HERPUD1 | 23592263 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000031E12 | HERPUD1 | 23592263 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000324096 | HERPUD1 | 23592263 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000043C1C3 | HERPUD1 | 23592263 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00005586D0 | HERPUD1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001CC4BD | HERPUD1 | 23592263 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000486E0B | HERPUD1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000021202F | HERPUD1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00005CCD18 | HERPUD1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000075CC78 | HERPUD1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000075D814 | HERPUD1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00001012BC | HERPUD1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00003AD2AA | HERPUD1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
VCP | HERPUD1 | 25348397 | N/A | physical interaction | ComPPI |
DERL2 | HERPUD1 | 25348397 | N/A | physical interaction | ComPPI |
USP7 | HERPUD1 | 14525934 16713569 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
ARHGDIA | HERPUD1 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
SIAH1 | HERPUD1 | 25348397 | N/A | physical interaction | ComPPI |
UBB | HERPUD1 | 25348397 | N/A | anti tag coimmunoprecipitation,covalent binding,physical interaction,comigration in sds page | ComPPI |
UBC | HERPUD1 | 25348397 | N/A | anti tag coimmunoprecipitation,covalent binding,physical interaction,physical interaction,comigration in sds page | ComPPI |
RPS27A | HERPUD1 | 25348397 | N/A | anti tag coimmunoprecipitation,covalent binding,physical interaction,comigration in sds page | ComPPI |
UBA52 | HERPUD1 | 25348397 | N/A | anti tag coimmunoprecipitation,covalent binding,physical interaction,comigration in sds page | ComPPI |
XRCC6 | HERPUD1 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
EWSR1 | HERPUD1 | 14525934 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
RPA2 | HERPUD1 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
SYVN1 | HERPUD1 | 16289116 21149444 23867461 25348397 26424800 26471130 27898060 | N/A | physical interaction | ComPPI,OmniPath |
UBQLN2 | HERPUD1 | 14525934 18307982 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
CD3D | HERPUD1 | 14525934 18307982 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
UBQLN4 | HERPUD1 | 25348397 | N/A | physical interaction | ComPPI |
SNCAIP | HERPUD1 | 25348397 | N/A | physical interaction | ComPPI |
PSMD2 | HERPUD1 | 25348397 | N/A | physical interaction | ComPPI |
TOLLIP | HERPUD1 | 20936779 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
SH3RF1 | HERPUD1 | 25348397 | N/A | physical interaction | ComPPI |
SNCA | HERPUD1 | 25348397 | N/A | physical interaction | ComPPI |
TRIM25 | HERPUD1 | 25348397 | N/A | physical interaction | ComPPI |
TBK1 | HERPUD1 | 25348397 | N/A | physical interaction | ComPPI |
UBQLN1 | HERPUD1 | 25348397 | N/A | physical interaction | ComPPI |
AMFR | HERPUD1 | 19223579 24234451 25348397 | N/A | pull down,physical interaction | ComPPI,IntAct |
SELENOS | HERPUD1 | 25348397 | N/A | physical interaction | ComPPI |
DERL1 | HERPUD1 | 25348397 | N/A | physical interaction | ComPPI |
IL23A | HERPUD1 | 25348397 | N/A | physical interaction | ComPPI |
PSEN1 | HERPUD1 | 11799129 14525934 14550564 25348397 27898060 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD,OmniPath |
HERPUD1 | CD58 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
HERPUD1 | STARD9 | 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
HERPUD1 | IMPA2 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
HERPUD1 | IL1R1 | 25348397 | N/A | physical interaction | ComPPI |
HERPUD1 | APP | 25348397 | N/A | physical interaction | ComPPI |
HERPUD1 | CAPN15 | 25348397 | N/A | physical interaction | ComPPI |
HERPUD1 | ATG9A | 25348397 | N/A | physical interaction | ComPPI |
HERPUD1 | SEL1L | 25348397 | N/A | physical interaction | ComPPI |
HERPUD1 | FAM8A1 | 25348397 | N/A | physical interaction | ComPPI |
HERPUD1 | UBXN6 | 18656546 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
C5AR2 | HERPUD1 | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |
CCR2 | HERPUD1 | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |
F2RL1 | HERPUD1 | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |
CHRM2 | HERPUD1 | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |