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GENE：NT5C3A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NT5C3A
FullNmae 5'-nucleotidase, cytosolic IIIA
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17820
EnsembleID ENSG00000122643
Uniprot Q9H0P0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NT5C3A pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NT5C3A autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NT5C3A apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NT5C3A GO:0000166,GO:0000215,GO:0000215,GO:0000287,GO:0005515,GO:0005654,GO:0005737,GO:0005737,GO:0005783,GO:0005829,GO:0005829,GO:0006213,GO:0008253,GO:0008253,GO:0008253,GO:0009117,GO:0016604,GO:0051607,GO:0106411

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NT5C3A hsa:51251 path:hsa00240 Pyrimidine metabolism - Homo sapiens (human)
NT5C3A hsa:51251 path:hsa01100 Metabolic pathways - Homo sapiens (human)
NT5C3A hsa:51251 path:hsa01232 Nucleotide metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 NT5C3A 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 NT5C3A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 NT5C3A 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 NT5C3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NT5C3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NT5C3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 NT5C3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NT5C3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NT5C3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NT5C3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 NT5C3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003380CC NT5C3A 23055569 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000065D58 NT5C3A 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase
URS00003380CC NT5C3A 23055569 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00003CF1AD NT5C3A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000B0E50 NT5C3A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003BD367 NT5C3A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000C7662 NT5C3A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002E92A8 NT5C3A 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TBC1D22B NT5C3A 25348397 N/A physical interaction ComPPI
CDC42 NT5C3A 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
BAG3 NT5C3A 25348397 N/A physical interaction ComPPI
DPEP1 NT5C3A 25348397 N/A physical interaction ComPPI
GNAQ NT5C3A 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KCNA5 NT5C3A 25348397 N/A physical interaction ComPPI
UBQLN2 NT5C3A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HTR2C NT5C3A 25348397 N/A physical interaction ComPPI
VANGL1 NT5C3A 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
GHITM NT5C3A 25348397 N/A physical interaction ComPPI
NT5C3A NDUFAB1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct

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