Gene Information gene info

GENE:PLEKHF1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PLEKHF1
FullNmae pleckstrin homology and FYVE domain containing 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20764
EnsembleID ENSG00000166289
Uniprot Q96S99

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PLEKHF1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PLEKHF1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PLEKHF1 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
PLEKHF1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PLEKHF1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
PLEKHF1 GO:0005515,GO:0005634,GO:0005764,GO:0005764,GO:0005765,GO:0005768,GO:0005769,GO:0006915,GO:0007032,GO:0007032,GO:0008333,GO:0010008,GO:0010314,GO:0010508,GO:0010508,GO:0016050,GO:0032266,GO:0035091,GO:0046872,GO:0048471,GO:0070273,GO:0072659,GO:2001244

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PLEKHF1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PLEKHF1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PLEKHF1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 PLEKHF1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 PLEKHF1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PLEKHF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PLEKHF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PLEKHF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PLEKHF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PLEKHF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PLEKHF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PLEKHF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PLEKHF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PLEKHF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PLEKHF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 PLEKHF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PLEKHF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 PLEKHF1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00001597DC PLEKHF1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CAVIN2 PLEKHF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CHIC2 PLEKHF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PLEKHF1 KIFBP 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PLEKHF1 L3MBTL3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct

Visualization