Gene Information gene info

GENE:PRG2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PRG2
FullNmae proteoglycan 2, pro eosinophil major basic protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9362
EnsembleID ENSG00000186652
Uniprot P13727

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PRG2 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PRG2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PRG2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PRG2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PRG2 GO:0002215,GO:0005515,GO:0005576,GO:0006955,GO:0008201,GO:0010936,GO:0030021,GO:0030021,GO:0030133,GO:0030246,GO:0032693,GO:0032753,GO:0042742,GO:0062023,GO:0070062,GO:1904813

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PRG2 hsa:5553 path:hsa05310 Asthma - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PRG2 GATA1 12202480 23180781 physical association electrophoretic mobility supershift assay InnateDB
SPI1 PRG2 12202480 23180781 physical association electrophoretic mobility supershift assay InnateDB
PRG2 CEBPB 12202480 23180781 physical association electrophoretic mobility supershift assay InnateDB
CEBPE PRG2 12202480 23180781 physical association electrophoretic mobility supershift assay InnateDB
PRG2 CSF2 23180781 7727786 physical association cosedimentation in solution InnateDB

Source Target Pmid Interactiontype Methods Database
GATA1 PRG2 10438731 12202480 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PRG2 10438731 19941826 9558404 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TP53 PRG2 18922183 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PRG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PRG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPE PRG2 12202480 trascriptional regulation,stimulation inferred by curator TFlink
NF1 PRG2 9765312 trascriptional regulation,stimulation inferred by curator TFlink
NFIB PRG2 1699939 trascriptional regulation,stimulation inferred by curator TFlink
SOX10 PRG2 11734543 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PRG2 12202480 trascriptional regulation,stimulation inferred by curator TFlink
CEBPB PRG2 N/A trascriptional regulation,stimulation inferred by curator TFlink
NFIC PRG2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
PRG2 PAPPA 25361965 interaction type N/A PTMCode2
PAPPA PRG2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CSF2 PRG2 14525934 25348397 27898060 7727786 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
ZMYND19 PRG2 25348397 N/A physical interaction ComPPI
GPRASP2 PRG2 25348397 N/A physical interaction ComPPI
COL6A2 PRG2 25348397 N/A physical interaction ComPPI
P3H4 PRG2 25348397 N/A physical interaction ComPPI
PAPPA PRG2 10913121 12421832 14525934 25348397 27898060 7685339 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
LDLR PRG2 25348397 N/A physical interaction ComPPI
PRG2 PRKCZ 10357815 11222751 14500673 14525934 25348397 9748166 N/A experimental interaction detection,in vitro ComPPI,HPRD
PRG2 RBM48 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PRG2 AGT 14525934 25348397 27898060 7539791 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
PRG2 AKT1 10698680 11278835 11445557 11546794 12149249 12176337 14500673 14525934 25348397 9736715 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PRG2 CHD3 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PRG2 SLC25A11 25348397 N/A physical interaction ComPPI
PRG2 SPEM1 25348397 N/A physical interaction ComPPI
PRG2 MC1R 25348397 N/A physical interaction ComPPI
PRG2 TUBB3 25348397 N/A physical interaction ComPPI
PRG2 TUBB8 25348397 N/A physical interaction ComPPI
PRG2 TUBB1 25348397 N/A physical interaction ComPPI
PRG2 WDR26 25348397 N/A physical interaction ComPPI
PRG2 HLA-A 25348397 N/A physical interaction ComPPI
PRG2 N4BP2L2 25348397 N/A physical interaction ComPPI
PRG2 ZNF460 25348397 N/A physical interaction ComPPI
PRG2 ACTA2 25348397 N/A physical interaction ComPPI
PRG2 POTEE 25348397 N/A physical interaction ComPPI
PRG2 PPP6R2 25348397 N/A physical interaction ComPPI
PRG2 ARMC8 25348397 N/A physical interaction ComPPI
PRG2 PATZ1 25348397 N/A physical interaction ComPPI
PRG2 MKLN1 25348397 N/A physical interaction ComPPI
PRG2 ADAMTS1 25348397 N/A physical interaction ComPPI
PRG2 MTFR1L 25348397 N/A physical interaction ComPPI
PRG2 DICER1 25348397 N/A physical interaction ComPPI
PRG2 MAEA 25348397 N/A physical interaction ComPPI
PRG2 TUBA4A 25348397 N/A physical interaction ComPPI
PRG2 TUBA1A 25348397 N/A physical interaction ComPPI
PRG2 RANBP10 25348397 N/A physical interaction ComPPI
PRG2 RANBP9 25348397 N/A physical interaction ComPPI
PRG2 RMND5A 25348397 N/A physical interaction ComPPI
PRG2 PASK 25348397 N/A physical interaction ComPPI
PRG2 FBN2 25348397 N/A physical interaction ComPPI
PRG2 PPP6R1 25348397 N/A physical interaction ComPPI
PRG2 GID4 25348397 N/A physical interaction ComPPI
PRG2 TOR3A 25348397 N/A physical interaction ComPPI
PRG2 PLEKHG4 25348397 N/A physical interaction ComPPI
PRG2 DUSP11 25348397 N/A physical interaction ComPPI
PRG2 ZMYM3 25348397 N/A physical interaction ComPPI
PRG2 FOXF2 25348397 N/A physical interaction ComPPI
PRG2 GID8 25348397 N/A physical interaction ComPPI
PRG2 VWDE 25348397 N/A physical interaction ComPPI
PRG2 ERGIC2 25348397 N/A physical interaction ComPPI
PRG2 FUT11 25348397 N/A physical interaction ComPPI
PRG2 YPEL5 25348397 N/A physical interaction ComPPI
PRG2 TRPC4AP 25348397 N/A physical interaction ComPPI
PRG2 MELK 25348397 N/A physical interaction ComPPI
PRG2 DVL2 25348397 N/A physical interaction ComPPI
PRG2 PHLDB3 25348397 N/A physical interaction ComPPI
PRG2 SELENON 25348397 N/A physical interaction ComPPI
PRG2 SIPA1L2 25348397 N/A physical interaction ComPPI
PRG2 THUMPD3 25348397 N/A physical interaction ComPPI
PRG2 ZSWIM8 25348397 N/A physical interaction ComPPI
PRG2 JMJD4 25348397 N/A physical interaction ComPPI
PRG2 ZNF589 25348397 N/A physical interaction ComPPI
PRG2 ADAMTS2 25348397 N/A physical interaction ComPPI
PRG2 TUBGCP6 25348397 N/A physical interaction ComPPI
PRG2 FOXF1 25348397 N/A physical interaction ComPPI
PRG2 ALG13 25348397 N/A physical interaction ComPPI
PRG2 GALNS 25348397 N/A physical interaction ComPPI
PRG2 PCSK5 25348397 N/A physical interaction ComPPI
PRG2 PPP1R9A 24234451 30021884 physical association cross-linking study IntAct

Visualization