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GENE：ICMT

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ICMT
FullNmae isoprenylcysteine carboxyl methyltransferase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5350
EnsembleID ENSG00000116237
Uniprot O60725

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ICMT immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ICMT autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ICMT GO:0003880,GO:0004671,GO:0004671,GO:0005515,GO:0005783,GO:0005783,GO:0005789,GO:0006481,GO:0006481,GO:0006612,GO:0016020,GO:0036211,GO:0046498,GO:0046499

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ICMT hsa:23463 path:hsa00900 Terpenoid backbone biosynthesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 ICMT 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink

Source Target Pmid Interactiontype Methods Database
URS00002C0FCB ICMT 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000DDD35 ICMT 20371350 21572407 23592263 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS000003ABC4 ICMT 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00001597DC ICMT 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000239117 ICMT 22012620 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS000055128B ICMT 22473208 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 ICMT 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 ICMT 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C ICMT 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004AE8D3 ICMT 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 ICMT 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA ICMT 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F ICMT 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 ICMT 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 ICMT 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 ICMT 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000136174 ICMT 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005586D0 ICMT 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0874 ICMT 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000527B00 ICMT 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000482389 ICMT 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000435A77 ICMT 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEE35 ICMT 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000021202F ICMT 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002D2333 ICMT 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 ICMT 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 ICMT 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C ICMT 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 ICMT 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 ICMT 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 ICMT 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE ICMT 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HRAS ICMT 25361965 interaction type N/A PTMCode2
ICMT HRAS 25361965 interaction type N/A PTMCode2
ICMT RAC1 25361965 interaction type N/A PTMCode2
RAC1 ICMT 25361965 interaction type N/A PTMCode2
ICMT ZMPSTE24 25361965 interaction type N/A PTMCode2
ZMPSTE24 ICMT 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
OXSR1 ICMT 25348397 N/A physical interaction ComPPI
GCA ICMT 25348397 N/A physical interaction ComPPI
TRIM32 ICMT 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RAC1 ICMT 12006387 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
HRAS ICMT 12750467 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
RHOA ICMT 14525934 25348397 9614111 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ICMT RAC2 14525934 25348397 9614111 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ICMT ELAVL1 25348397 N/A physical interaction ComPPI
ICMT DUSP1 25348397 N/A physical interaction ComPPI
ICMT DUSP28 25348397 N/A physical interaction ComPPI
ICMT RAD51D 25348397 N/A physical interaction ComPPI
ICMT PCCA 25348397 N/A physical interaction ComPPI
ICMT STXBP3 25348397 N/A physical interaction ComPPI
ICMT PPM1E 25348397 N/A physical interaction ComPPI
ICMT TRIM25 25348397 N/A physical interaction ComPPI
ICMT PDZK1IP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ICMT ARL13B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ICMT RNF19B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ICMT KCNJ6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ICMT AQP6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ICMT CANX 24234451 25348397 29568061 association pull down ComPPI,IntAct
CLN6 ICMT 24234451 30177828 association anti tag coimmunoprecipitation IntAct
ICMT HRAS 12750467 27898060 N/A N/A OmniPath

Visualization










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