Gene Information gene info

GENE:AGPAT1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol AGPAT1
FullNmae 1-acylglycerol-3-phosphate O-acyltransferase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:324
EnsembleID ENSG00000204310
Uniprot Q99943

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
AGPAT1 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
AGPAT1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
AGPAT1 GO:0001819,GO:0001961,GO:0003841,GO:0003841,GO:0003841,GO:0003841,GO:0005515,GO:0005783,GO:0005783,GO:0005789,GO:0006644,GO:0006654,GO:0006654,GO:0006654,GO:0016020,GO:0016024

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
AGPAT1 hsa:10554 path:hsa00561 Glycerolipid metabolism - Homo sapiens (human)
AGPAT1 hsa:10554 path:hsa00564 Glycerophospholipid metabolism - Homo sapiens (human)
AGPAT1 hsa:10554 path:hsa01100 Metabolic pathways - Homo sapiens (human)
AGPAT1 hsa:10554 path:hsa04072 Phospholipase D signaling pathway - Homo sapiens (human)
AGPAT1 hsa:10554 path:hsa04975 Fat digestion and absorption - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 AGPAT1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 AGPAT1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 AGPAT1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 AGPAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA AGPAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF AGPAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS AGPAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A AGPAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 AGPAT1 20304954 25416803 mrna cleavage,inhibition array technology TarBase
URS00003AA845 AGPAT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB AGPAT1 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
BAG3 AGPAT1 25348397 N/A physical interaction ComPPI
AGPAT1 ELAVL1 25348397 N/A physical interaction ComPPI
AGPAT1 UPF2 25348397 N/A physical interaction ComPPI
AGPAT1 MOV10 25348397 N/A physical interaction ComPPI
AGPAT1 NXF1 25348397 N/A physical interaction ComPPI
AGPAT1 HAVCR2 25348397 N/A physical interaction ComPPI
AGPAT1 TNFRSF17 25348397 N/A physical interaction ComPPI
AGPAT1 TRIM25 25348397 N/A physical interaction ComPPI
AGPAT1 MYC 21150319 24234451 25348397 association tandem affinity purification ComPPI,IntAct
WTAP AGPAT1 24234451 29507755 association anti tag coimmunoprecipitation IntAct

Visualization