GeneInfo:
| GeneAttribute |
GeneDescription |
| GeneSymbol |
ISOC1 |
| FullNmae |
isochorismatase domain containing 1 |
| LocusType |
gene with protein product |
| Status |
Approved |
| HGNC_id |
HGNC:24254 |
| EnsembleID |
ENSG00000066583 |
| Uniprot |
Q96CN7 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
| ISOC1 |
autosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
| GeneSymbol |
Go id |
| ISOC1 |
GO:0003674,GO:0005515,GO:0005737,GO:0005777,GO:0008150 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| ETS1 |
ISOC1 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
| GATA2 |
ISOC1 |
18971253
19941826
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
| PRDM14 |
ISOC1 |
18971253
20953172
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
| SMARCA4 |
ISOC1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CEBPA |
ISOC1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CTCF |
ISOC1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| E2F1 |
ISOC1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| E2F4 |
ISOC1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| EGR1 |
ISOC1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOXA1 |
ISOC1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| HNF4A |
ISOC1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| URS0000013DD8 |
ISOC1 |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
| URS000006F90B |
ISOC1 |
21572407
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS000041E949 |
ISOC1 |
21572407
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS0000346991 |
ISOC1 |
21572407
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS0000277201 |
ISOC1 |
21572407
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS000025EABA |
ISOC1 |
21572407
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00000DDD35 |
ISOC1 |
21572407
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS0000298BA3 |
ISOC1 |
21572407
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00002B3783 |
ISOC1 |
21572407
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS0000042E1F |
ISOC1 |
21572407
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00002075FA |
ISOC1 |
21572407
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00000600E6 |
ISOC1 |
21572407
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS000039E1E1 |
ISOC1 |
21572407
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| PAK2 |
ISOC1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| VTN |
ISOC1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| CAPNS1 |
ISOC1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
ELAVL1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
ASNS |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
ATIC |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
DFFA |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
EIF5 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
FERMT2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
G6PD |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
MCTS1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
STK26 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
MYO1E |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
PPP1R2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
PRCP |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
PTMA |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
STK24 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
TBCB |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
TUBB4B |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
PAFAH1B1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
UBFD1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
VCL |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
YWHAE |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
YWHAH |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
YWHAZ |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
MTHFD1L |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
NTRK1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
NIN |
24234451
25348397
26638075
|
association |
physical interaction,proximity-dependent biotin identification |
ComPPI,IntAct |
| ISOC1 |
EVC2 |
24234451
25348397
26638075
|
association |
physical interaction,proximity-dependent biotin identification |
ComPPI,IntAct |
| ISOC1 |
ARHGAP8 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ISOC1 |
JUN |
24234451
25348397
25609649
|
association |
anti bait coimmunoprecipitation |
ComPPI,IntAct |
| ISOC1 |
CAT |
24234451
25348397
29568061
|
association |
proximity-dependent biotin identification |
ComPPI,IntAct |
Visualization