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GENE：MTPAP

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MTPAP
FullNmae mitochondrial poly(A) polymerase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25532
EnsembleID ENSG00000107951
Uniprot Q9NVV4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MTPAP autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MTPAP GO:0000287,GO:0002134,GO:0003723,GO:0005515,GO:0005524,GO:0005654,GO:0005739,GO:0005739,GO:0006378,GO:0006378,GO:0030145,GO:0042802,GO:0042803,GO:0043231,GO:0071044,GO:1990817,GO:1990817

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CALCOCO2 MTPAP 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
AZI2 MTPAP 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
TBK1 MTPAP 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 MTPAP 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 MTPAP 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 MTPAP 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 MTPAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MTPAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MTPAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MTPAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MTPAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 MTPAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 MTPAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000122ED0 MTPAP 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00000DDD35 MTPAP 20371350 21572407 22012620 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS00000CF1D2 MTPAP 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 MTPAP 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 MTPAP 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 MTPAP 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 MTPAP 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD002 MTPAP 21572407 23446348 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00006DE17B MTPAP 21572407 22012620 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000003BF62 MTPAP 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000DD591 MTPAP 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA MTPAP 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000025EABA MTPAP 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 MTPAP 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 MTPAP 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F MTPAP 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA MTPAP 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 MTPAP 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 MTPAP 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B MTPAP 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000C85B2 MTPAP 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000007F792 MTPAP 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000075AB0E MTPAP 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000A2C49 MTPAP 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075C4B1 MTPAP 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 MTPAP 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 MTPAP 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003B59DF MTPAP 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000043C1C3 MTPAP 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003FBC84 MTPAP 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001C0099 MTPAP 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000006372A MTPAP 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001CC4BD MTPAP 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000355E82 MTPAP 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
DYNLL1 MTPAP 24234451 25348397 26496610 27173435 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DYNLL2 MTPAP 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
NPM1 MTPAP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NF2 MTPAP 25348397 N/A physical interaction ComPPI
RPL10 MTPAP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JUN MTPAP 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
LRP1 MTPAP 25348397 N/A physical interaction ComPPI
EID1 MTPAP 25348397 N/A physical interaction ComPPI
THBS3 MTPAP 25348397 N/A physical interaction ComPPI
TBK1 MTPAP 21903422 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELAVL1 MTPAP 25348397 N/A physical interaction ComPPI
CD79A MTPAP 25348397 N/A physical interaction ComPPI
CALCOCO2 MTPAP 21903422 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMILIN1 MTPAP 25348397 N/A physical interaction ComPPI
STK25 MTPAP 25348397 N/A physical interaction ComPPI
FOXS1 MTPAP 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
AZI2 MTPAP 25348397 N/A physical interaction ComPPI
LGALS7 MTPAP 25348397 N/A physical interaction ComPPI
NCL MTPAP 25348397 N/A physical interaction ComPPI
RIPK4 MTPAP 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
THBS4 MTPAP 25348397 N/A physical interaction ComPPI
MRPL58 MTPAP 20186120 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
GRSF1 MTPAP 25348397 N/A physical interaction ComPPI
YBEY MTPAP 25348397 N/A physical interaction ComPPI
MTPAP SPACA1 25348397 N/A physical interaction ComPPI
MTPAP FOXI2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
MTPAP VWA5A 25348397 N/A physical interaction ComPPI
MTPAP TSPYL6 25348397 N/A physical interaction ComPPI
CI MTPAP 15710747 24234451 25348397 physical association physical interaction,two hybrid fragment pooling approach ComPPI,IntAct
MTPAP MTPAP 21292163 24234451 N/A light scattering,molecular sieving,x-ray crystallography IntAct
TBK1 MTPAP 21903422 27898060 N/A N/A OmniPath
AZI2 MTPAP 21903422 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00008C0D8A MTPAP 27087310 direct interaction,inhibition N/A NPInter

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