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GENE：APBB1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol APBB1
FullNmae amyloid beta precursor protein binding family B member 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:581
EnsembleID ENSG00000166313
Uniprot O00213

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
APBB1 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
APBB1 GO:0000122,GO:0001540,GO:0003682,GO:0003713,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0005783,GO:0005886,GO:0006325,GO:0006355,GO:0006915,GO:0006939,GO:0006974,GO:0007165,GO:0007409,GO:0008134,GO:0016607,GO:0030027,GO:0030426,GO:0031625,GO:0042393,GO:0043065,GO:0045202,GO:0045893,GO:0045944,GO:0050714,GO:0050750,GO:0070064,GO:1902807

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
APBB1 hsa:322 path:hsa05010 Alzheimer disease - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP APBB1 16049941 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
SMARCA4 APBB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 APBB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 APBB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A APBB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 APBB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SP1 APBB1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 APBB1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000521626 APBB1 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS00001597DC APBB1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
SGK1 APBB1 22135298 phosphorylation N/A PhosphoSite
MAPK1 APBB1 22135298 phosphorylation N/A PhosphoSite
APLP2 APBB1 25361965 interaction type N/A PTMCode2
APBB1 APLP2 25361965 interaction type N/A PTMCode2
VASP APBB1 25361965 interaction type N/A PTMCode2
APBB1 VASP 25361965 interaction type N/A PTMCode2
TSHZ3 APBB1 25361965 interaction type N/A PTMCode2
APBB1 TSHZ3 25361965 interaction type N/A PTMCode2
TFCP2 APBB1 25361965 interaction type N/A PTMCode2
APBB1 TFCP2 25361965 interaction type N/A PTMCode2
APBB1 TSHZ1 25361965 interaction type N/A PTMCode2
TSHZ1 APBB1 25361965 interaction type N/A PTMCode2
APBB1 KAT5 25361965 interaction type N/A PTMCode2
KAT5 APBB1 25361965 interaction type N/A PTMCode2
APBB1 ENAH 25361965 interaction type N/A PTMCode2
ENAH APBB1 25361965 interaction type N/A PTMCode2
APBB1 ABL1 25361965 interaction type N/A PTMCode2
ABL1 APBB1 25361965 interaction type N/A PTMCode2
APBB1 CLSTN1 25361965 interaction type N/A PTMCode2
CLSTN1 APBB1 25361965 interaction type N/A PTMCode2
APBB1 EVL 25361965 interaction type N/A PTMCode2
EVL APBB1 25361965 interaction type N/A PTMCode2
APP APBB1 25361965 interaction type N/A PTMCode2
APBB1 APP 25361965 interaction type N/A PTMCode2
APLP1 APBB1 25361965 interaction type N/A PTMCode2
APBB1 APLP1 25361965 interaction type N/A PTMCode2
LRP2 APBB1 25361965 interaction type N/A PTMCode2
APBB1 LRP2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SF3A3 APBB1 25348397 N/A physical interaction ComPPI
HNRNPK APBB1 25348397 N/A physical interaction ComPPI
RBM17 APBB1 25348397 N/A physical interaction ComPPI
WASL APBB1 25348397 N/A physical interaction ComPPI
DHX15 APBB1 25348397 N/A physical interaction ComPPI
VASP APBB1 14525934 16055720 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ANXA1 APBB1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
WAS APBB1 25348397 N/A physical interaction ComPPI
SET APBB1 15592452 25348397 27898060 N/A physical interaction ComPPI,OmniPath
YWHAG APBB1 25348397 N/A physical interaction ComPPI
ATXN1 APBB1 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SF3B4 APBB1 25348397 N/A physical interaction ComPPI
TSHZ3 APBB1 19343227 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CPSF7 APBB1 25348397 N/A physical interaction ComPPI
DDX17 APBB1 25348397 N/A physical interaction ComPPI
ERBB2 APBB1 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
SF3A2 APBB1 25348397 N/A physical interaction ComPPI
MAPK8 APBB1 19234442 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
NOTCH1 APBB1 25348397 N/A physical interaction ComPPI
KHDRBS1 APBB1 25348397 N/A physical interaction ComPPI
EVL APBB1 10945997 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
DHX9 APBB1 25348397 N/A physical interaction ComPPI
SF3B1 APBB1 25348397 N/A physical interaction ComPPI
NONO APBB1 25348397 N/A physical interaction ComPPI
SFPQ APBB1 25348397 N/A physical interaction ComPPI
U2AF2 APBB1 25348397 N/A physical interaction ComPPI
WBP11 APBB1 25348397 N/A physical interaction ComPPI
PRNP APBB1 14525934 15146195 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
YBX1 APBB1 25348397 N/A physical interaction ComPPI
DIAPH1 APBB1 25348397 N/A physical interaction ComPPI
ENAH APBB1 14525934 16055720 25348397 27898060 9407065 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
WIPF2 APBB1 25348397 N/A physical interaction ComPPI
APBB1 LRP1 11729193 14525934 15115822 16382151 21968187 24234451 25348397 27898060 9837937 physical association two hybrid,experimental interaction detection,nuclear magnetic resonance,pull down,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct,OmniPath
APBB1 TFCP2 14525934 25348397 27898060 9685356 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
APBB1 CLSTN1 14525934 15037614 17332754 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,in vivo ComPPI,HPRD,IntAct
APBB1 KAT5 11441186 14525934 14699153 15044485 15331662 16223726 17368826 25342469 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
APBB1 FASLG 11741599 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
APBB1 APLP1 14525934 25348397 8894693 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
APBB1 APLP2 14525934 24234451 25348397 8894693 9461550 physical association two hybrid,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
APBB1 APP 10081969 10373567 11085987 11517249 14525934 15044485 15331662 16049941 16223726 17368826 18096514 18833287 20205790 23663107 24234451 25348397 27898060 8855266 8887653 8894693 8955346 9045663 9321393 9461550 9799084 9837937 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD,IntAct,OmniPath
APBB1 TSHZ1 25348397 N/A physical interaction ComPPI
APBB1 TSHZ2 25348397 N/A physical interaction ComPPI
APBB1 HDAC1 25348397 N/A physical interaction ComPPI
APBB1 CPSF6 25348397 N/A physical interaction ComPPI
APBB1 CUL4B 25348397 N/A physical interaction ComPPI
APBB1 ATXN1L 25348397 N/A physical interaction ComPPI
APBB1 EGFR 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
APBB1 HTATSF1 25348397 N/A physical interaction ComPPI
APBB1 PQBP1 25348397 N/A physical interaction ComPPI
APBB1 THRAP3 25348397 N/A physical interaction ComPPI
APBB1 DDX3X 25348397 N/A physical interaction ComPPI
APBB1 DDX46 25348397 N/A physical interaction ComPPI
APBB1 HNRNPH1 25348397 N/A physical interaction ComPPI
APBB1 KHSRP 25348397 N/A physical interaction ComPPI
APBB1 PABPC1 25348397 N/A physical interaction ComPPI
APBB1 PTBP1 25348397 N/A physical interaction ComPPI
APBB1 SF1 25348397 N/A physical interaction ComPPI
APBB1 SF3A1 25348397 N/A physical interaction ComPPI
APBB1 SF3B2 25348397 N/A physical interaction ComPPI
APBB1 SF3B3 25348397 N/A physical interaction ComPPI
APBB1 RPL4 25348397 N/A physical interaction ComPPI
APBB1 CYFIP1 25348397 N/A physical interaction ComPPI
APBB1 CYFIP2 25348397 N/A physical interaction ComPPI
APBB1 DIAPH2 25348397 N/A physical interaction ComPPI
APBB1 ABI1 25348397 N/A physical interaction ComPPI
APBB1 WASF2 25348397 N/A physical interaction ComPPI
APBB1 WIPF1 25348397 N/A physical interaction ComPPI
APBB1 CHERP 25348397 N/A physical interaction ComPPI
APBB1 YLPM1 25348397 N/A physical interaction ComPPI
APBB1 CCDC97 25348397 N/A physical interaction ComPPI
APBB1 MGRN1 25348397 N/A physical interaction ComPPI
APBB1 SART3 25348397 N/A physical interaction ComPPI
APBB1 SLAMF7 25348397 N/A physical interaction ComPPI
APBB1 APBB2 25348397 N/A physical interaction ComPPI
APBB1 PCGF6 25348397 N/A physical interaction ComPPI
APBB1 QTRT1 25348397 N/A physical interaction ComPPI
APBB1 THBS4 25348397 N/A physical interaction ComPPI
APBB1 THBS3 25348397 N/A physical interaction ComPPI
APBB1 CEP104 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
APBB1 CEP44 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
APBB1 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
APBB1 TMEM216 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
APBB1 JAG1 25348397 26276215 27898060 N/A physical interaction ComPPI,OmniPath
APBB1 NEURL1 25348397 N/A physical interaction ComPPI
APBB1 BLM 25348397 N/A physical interaction ComPPI
APBB1 SYDE1 25348397 N/A physical interaction ComPPI
APBB1 NEURL4 25348397 N/A physical interaction ComPPI
APBB1 HERC2 25348397 N/A physical interaction ComPPI
APBB1 HERC2P3 25348397 N/A physical interaction ComPPI
APBB1 DCAKD 25348397 N/A physical interaction ComPPI
APBB1 SYP 25348397 N/A physical interaction ComPPI
APBB1 SETX 25348397 N/A physical interaction ComPPI
APBB1 TAMM41 25348397 N/A physical interaction ComPPI
APBB1 LMO2 25348397 N/A physical interaction ComPPI
APBB1 H2AX 19234442 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NEDD4L APBB1 19381069 25348397 27898060 N/A physical interaction ComPPI,OmniPath
APBB1 ABL1 11279131 14525934 N/A experimental interaction detection HPRD
APBB1 LRP2 14525934 9837937 N/A experimental interaction detection,two hybrid HPRD
APBB1 APBB1 14525934 9407065 N/A experimental interaction detection HPRD
ABL1 APBB1 11279131 15031292 18922798 20841568 27898060 stimulant N/A OmniPath
MAPK1 APBB1 14697653 27898060 stimulant N/A OmniPath
SGK1 APBB1 26188042 27898060 N/A N/A OmniPath

Visualization










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