GENE:RPS6KC1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | RPS6KC1 |
| FullNmae | ribosomal protein S6 kinase C1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:10439 |
| EnsembleID | ENSG00000136643 |
| Uniprot | Q96S38 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| RPS6KC1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| RPS6KC1 | GO:0004674,GO:0005515,GO:0005524,GO:0005764,GO:0005768,GO:0005769,GO:0005769,GO:0007165,GO:0016020,GO:0016310,GO:0035091,GO:0106310 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | RPS6KC1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | RPS6KC1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | RPS6KC1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | RPS6KC1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| PRDM14 | RPS6KC1 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | RPS6KC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | RPS6KC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | RPS6KC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | RPS6KC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | RPS6KC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | RPS6KC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | RPS6KC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | RPS6KC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | RPS6KC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | RPS6KC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | RPS6KC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | RPS6KC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | RPS6KC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | RPS6KC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | RPS6KC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| PBX2 | RPS6KC1 | 14525934 14667819 24234451 25348397 | physical association | two hybrid,two hybrid | ComPPI,HPRD,IntAct |
| HSP90AB1 | RPS6KC1 | 22939624 24234451 25348397 | physical association | luminescence based mammalian interactome mapping | ComPPI,IntAct |
| HSP90AA1 | RPS6KC1 | 25348397 | N/A | physical interaction | ComPPI |
| IQGAP1 | RPS6KC1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| SPHK1 | RPS6KC1 | 12077123 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD |
| TGOLN2 | RPS6KC1 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| RPS6KC1 | PRDX3 | 14525934 15750338 21988832 24234451 25348397 | physical association | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD,IntAct |
| RPS6KC1 | HSP90AA2P | 25348397 | N/A | physical interaction | ComPPI |
| RPS6KC1 | DENND6A | 24234451 25348397 25852190 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| RPS6KC1 | VPS39 | 25348397 | N/A | physical interaction | ComPPI |
| RPS6KC1 | ETS1 | 20195357 24234451 25348397 | physical association | display technology | ComPPI,IntAct |
| RPS6KC1 | RPS6KC1 | 12077123 14525934 | N/A | experimental interaction detection | HPRD |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00009B07C1 | RPS6KC1 | 27087310 | direct interaction,inhibition | N/A | NPInter |
