Gene Information gene info

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GENE：ERLIN2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ERLIN2
FullNmae ER lipid raft associated 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1356
EnsembleID ENSG00000147475
Uniprot O94905

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ERLIN2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ERLIN2 GO:0005515,GO:0005783,GO:0005789,GO:0005789,GO:0005789,GO:0005829,GO:0005886,GO:0005886,GO:0008203,GO:0015485,GO:0030433,GO:0031625,GO:0032933,GO:0032933,GO:0032991,GO:0045121,GO:0045121,GO:0045540,GO:0045541,GO:0045717

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 ERLIN2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ERLIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ERLIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ERLIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ERLIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ERLIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 ERLIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000B59A2 ERLIN2 16822819 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EED18 ERLIN2 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000A939F ERLIN2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000DDD35 ERLIN2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
ERLIN1 ERLIN2 21343306 24234451 25348397 30021884 association,physical association cross-linking study,physical interaction,tandem affinity purification ComPPI,IntAct
TUBB ERLIN2 25348397 N/A physical interaction ComPPI
RNF5 ERLIN2 25348397 N/A physical interaction ComPPI
NF2 ERLIN2 25348397 N/A physical interaction ComPPI
JUN ERLIN2 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
ADRA1D ERLIN2 25348397 N/A physical interaction ComPPI
VAPA ERLIN2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAB7A ERLIN2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBC ERLIN2 25348397 N/A physical interaction ComPPI
NTRK1 ERLIN2 25348397 N/A physical interaction ComPPI
CANX ERLIN2 21343306 24234451 25348397 29568061 association pull down,physical interaction,tandem affinity purification ComPPI,IntAct
FAP ERLIN2 25348397 N/A physical interaction ComPPI
DUSP3 ERLIN2 25348397 N/A physical interaction ComPPI
HAX1 ERLIN2 21343306 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
KRT7 ERLIN2 25348397 N/A physical interaction ComPPI
HSPA5 ERLIN2 21343306 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
HSPA1A ERLIN2 21343306 24234451 25348397 association tandem affinity purification ComPPI,IntAct
HSP90B1 ERLIN2 21343306 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SEC61B ERLIN2 21343306 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CASP8 ERLIN2 25348397 N/A physical interaction ComPPI
SREBF1 ERLIN2 25348397 N/A physical interaction ComPPI
SREBF2 ERLIN2 25348397 N/A physical interaction ComPPI
DCTN1 ERLIN2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CFTR ERLIN2 25348397 N/A physical interaction ComPPI
VDAC1 ERLIN2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
EWSR1 ERLIN2 25348397 N/A physical interaction ComPPI
RAB2A ERLIN2 25348397 N/A physical interaction ComPPI
SYVN1 ERLIN2 21343306 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ADRB2 ERLIN2 25348397 N/A physical interaction ComPPI
TUBA1A ERLIN2 25348397 N/A physical interaction ComPPI
CD3D ERLIN2 25348397 N/A physical interaction ComPPI
TCP1 ERLIN2 21343306 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
TUBA8 ERLIN2 25348397 N/A physical interaction ComPPI
HSPA4 ERLIN2 25348397 N/A physical interaction ComPPI
TFDP1 ERLIN2 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
TRIM28 ERLIN2 21343306 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MMS19 ERLIN2 25348397 N/A physical interaction ComPPI
NCSTN ERLIN2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD2 ERLIN2 25348397 N/A physical interaction ComPPI
CSE1L ERLIN2 21343306 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
RNF139 ERLIN2 21343306 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATP2A2 ERLIN2 21343306 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PDCD6 ERLIN2 25348397 N/A physical interaction ComPPI
SCAP ERLIN2 25348397 N/A physical interaction ComPPI
INSIG1 ERLIN2 21343306 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
STK3 ERLIN2 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ELAVL1 ERLIN2 25348397 N/A physical interaction ComPPI
APH1A ERLIN2 25348397 N/A physical interaction ComPPI
PSENEN ERLIN2 25348397 N/A physical interaction ComPPI
AMFR ERLIN2 21343306 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DERL1 ERLIN2 25348397 N/A physical interaction ComPPI
EEF2 ERLIN2 25348397 N/A physical interaction ComPPI
TCF3 ERLIN2 25348397 N/A physical interaction ComPPI
BET1 ERLIN2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ITPR1 ERLIN2 17502376 19240031 25348397 25882839 27898060 N/A physical interaction ComPPI,OmniPath
FAF2 ERLIN2 25348397 N/A physical interaction ComPPI
HNRNPM ERLIN2 25348397 N/A physical interaction ComPPI
FLOT1 ERLIN2 25348397 N/A physical interaction ComPPI
ICOS ERLIN2 24234451 25348397 27135603 association anti bait coimmunoprecipitation ComPPI,IntAct
UFD1 ERLIN2 25348397 N/A physical interaction ComPPI
TIMM50 ERLIN2 21343306 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PSEN1 ERLIN2 25348397 N/A physical interaction ComPPI
CYLD ERLIN2 25348397 N/A physical interaction ComPPI
ECH1 ERLIN2 24234451 25348397 29426014 association anti tag coimmunoprecipitation ComPPI,IntAct
AIFM1 ERLIN2 21343306 24234451 25348397 association tandem affinity purification ComPPI,IntAct
PPP6R3 ERLIN2 25348397 N/A physical interaction ComPPI
CCT2 ERLIN2 25348397 N/A physical interaction ComPPI
CCDC47 ERLIN2 21343306 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
TMEM259 ERLIN2 25348397 N/A physical interaction ComPPI
SRPRB ERLIN2 21343306 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SCLT1 ERLIN2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
FLOT2 ERLIN2 25348397 N/A physical interaction ComPPI
FBXO6 ERLIN2 25348397 N/A physical interaction ComPPI
HMGCR ERLIN2 21343306 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
FN1 ERLIN2 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
MLF2 ERLIN2 21343306 24234451 25348397 association tandem affinity purification ComPPI,IntAct
CLN3 ERLIN2 25348397 N/A physical interaction ComPPI
PLEKHA7 ERLIN2 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
HNRNPUL2 ERLIN2 25348397 N/A physical interaction ComPPI
FKBP14 ERLIN2 25348397 N/A physical interaction ComPPI
ERLIN2 RHOT1 21343306 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
ERLIN2 GOLT1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CLN6 ERLIN2 24234451 30177828 association anti tag coimmunoprecipitation IntAct
ERLIN2 PRRC2B 24234451 30021884 physical association cross-linking study IntAct

Visualization










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