Gene Information gene info

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GENE：DOK4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DOK4
FullNmae docking protein 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19868
EnsembleID ENSG00000125170
Uniprot Q8TEW6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DOK4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DOK4 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DOK4 GO:0005515,GO:0005737,GO:0005829,GO:0007169,GO:0007265,GO:0007399,GO:0043410

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RET DOK4 11470823 23331499 stimulation N/A SignaLink
INSR DOK4 12730241 23331499 stimulation N/A SignaLink
DOK4 CRK 12730241 23331499 stimulation N/A SignaLink
DOK4 SRC 12730241 23331499 stimulation N/A SignaLink
DOK4 FYN 12730241 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
DOK4 ERBB2 20005715 interaction type N/A PSP,SignaLink
DOK4 INSR 20005715 interaction type N/A PSP,SignaLink
DOK4 FYN 20005715 interaction type N/A PSP,SignaLink
DOK4 RET 20005715 interaction type N/A PSP
DOK4 IGF1R 20005715 interaction type N/A PSP,SignaLink
DOK4 SRC 20005715 interaction type N/A PSP,SignaLink
DOK4 TEK 20005715 interaction type N/A PSP
DOK4 RET 11470823 18988627 20005715 20005715 N/A N/A SignaLink
DOK4 TEK 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
GATA2 DOK4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 DOK4 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA DOK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DOK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DOK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DOK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 DOK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004505E4 DOK4 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
DOK4 RET 25361965 interaction type N/A PTMCode2
RET DOK4 25361965 interaction type N/A PTMCode2
DOK4 SRC 25361965 interaction type N/A PTMCode2
SRC DOK4 25361965 interaction type N/A PTMCode2
DOK4 FYN 25361965 interaction type N/A PTMCode2
FYN DOK4 25361965 interaction type N/A PTMCode2
CRK DOK4 25361965 interaction type N/A PTMCode2
DOK4 CRK 25361965 interaction type N/A PTMCode2
INSR DOK4 25361965 interaction type N/A PTMCode2
DOK4 INSR 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
BAG3 DOK4 25348397 N/A physical interaction ComPPI
KBTBD7 DOK4 25348397 N/A physical interaction ComPPI
CRK DOK4 12730241 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
ERBB2 DOK4 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
SRC DOK4 12730241 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
DOK3 DOK4 25348397 N/A physical interaction ComPPI
FHL2 DOK4 25348397 N/A physical interaction ComPPI
OPRK1 DOK4 25348397 N/A physical interaction ComPPI
OPRD1 DOK4 25348397 N/A physical interaction ComPPI
OPRM1 DOK4 23840749 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct
STAT2 DOK4 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,validated two hybrid ComPPI,IntAct
PHKG2 DOK4 25348397 N/A physical interaction ComPPI
HMG20A DOK4 25348397 N/A physical interaction ComPPI
PHKA2 DOK4 25348397 N/A physical interaction ComPPI
RET DOK4 11470823 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
EGFR DOK4 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
RASA1 DOK4 12730241 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
MIER1 DOK4 25348397 N/A physical interaction ComPPI
PFDN5 DOK4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DOK4 INSR 12730241 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
DOK4 FYN 12730241 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
DOK4 ELAVL1 25348397 N/A physical interaction ComPPI
DOK4 KDM1A 25348397 N/A physical interaction ComPPI
DOK4 GSE1 25348397 N/A physical interaction ComPPI
DOK4 SMARCAD1 25348397 N/A physical interaction ComPPI
DOK4 PBK 25348397 N/A physical interaction ComPPI
DOK4 RCOR1 25348397 N/A physical interaction ComPPI
DOK4 RCOR3 25348397 N/A physical interaction ComPPI
DOK4 PHKB 25348397 N/A physical interaction ComPPI
DOK4 AHCYL2 25348397 N/A physical interaction ComPPI
DOK4 AHCYL1 25348397 N/A physical interaction ComPPI
DOK4 SUPT5H 25348397 N/A physical interaction ComPPI
DOK4 KBTBD6 25348397 N/A physical interaction ComPPI
DOK4 CWC22 25348397 N/A physical interaction ComPPI
DOK4 ANK3 25348397 N/A physical interaction ComPPI
DOK4 CCM2 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,luminescence based mammalian interactome mapping,validated two hybrid ComPPI,IntAct
DOK4 PTK2 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,validated two hybrid ComPPI,IntAct
DOK4 LIX1 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DOK4 OLIG1 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DOK4 RBP7 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DOK4 MAPRE3 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DOK4 RHOU 25348397 N/A physical interaction ComPPI
DOK4 SUPT4H1 25348397 N/A physical interaction ComPPI
DOK4 PAX8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DOK4 INCA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGF1R DOK4 12730241 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
TEK DOK4 11470823 14525934 N/A experimental interaction detection HPRD
DOK4 SRC 12730241 27898060 stimulant N/A OmniPath
DOK4 FYN 12730241 27898060 stimulant N/A OmniPath
RET DOK4 11470823 27898060 stimulant N/A OmniPath
DOK4 CRK 12730241 27898060 stimulant N/A OmniPath

Visualization










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