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GENE：RYBP

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RYBP
FullNmae RING1 and YY1 binding protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10480
EnsembleID ENSG00000163602
Uniprot Q8N488

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RYBP pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RYBP autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RYBP GO:0000122,GO:0003676,GO:0003677,GO:0003712,GO:0003714,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0006338,GO:0006355,GO:0006915,GO:0031519,GO:0032435,GO:0043065,GO:0045893,GO:0046872

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RYBP hsa:23429 path:hsa03083 Polycomb repressive complex - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EED RYBP 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
RNF2 RYBP 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
BMI1 RYBP 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
RYBP ELAVL1 19322201 23180781 physical association anti tag coimmunoprecipitation InnateDB
RYBP ABL1 23331499 8943360 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR RYBP 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 RYBP 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 RYBP 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 RYBP 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 RYBP 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C RYBP 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 RYBP 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 RYBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RYBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RYBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 RYBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RYBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RYBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 RYBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RYBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RYBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF RYBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 RYBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 RYBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 RYBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 RYBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 RYBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000DDD35 RYBP 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000D5659 RYBP 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5BAA RYBP 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000016C318 RYBP 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00005E6F45 RYBP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002FF522 RYBP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000010BD8D RYBP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075A513 RYBP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA RYBP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000260A3A RYBP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000038718E RYBP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 RYBP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A RYBP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 RYBP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 RYBP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000039A25B RYBP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F RYBP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 RYBP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE RYBP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 RYBP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000037B2E0 RYBP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000319E1 RYBP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000496C56 RYBP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 RYBP 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F RYBP 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
YY1 RYBP 25361965 interaction type N/A PTMCode2
RYBP YY1 25361965 interaction type N/A PTMCode2
CBX2 RYBP 25361965 interaction type N/A PTMCode2
RYBP CBX2 25361965 interaction type N/A PTMCode2
RING1 RYBP 25361965 interaction type N/A PTMCode2
RYBP RING1 25361965 interaction type N/A PTMCode2
RNF2 RYBP 25361965 interaction type N/A PTMCode2
RYBP RNF2 25361965 interaction type N/A PTMCode2
BCOR RYBP 25361965 interaction type N/A PTMCode2
RYBP BCOR 25361965 interaction type N/A PTMCode2
FADD RYBP 25361965 interaction type N/A PTMCode2
RYBP FADD 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
E2F6 RYBP 11171983 24234451 25348397 27705803 association,physical association two hybrid,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,IntAct
SKP1 RYBP 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
GABPB1 RYBP 11953439 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
BMI1 RYBP 20601937 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
RING1 RYBP 10369680 14525934 16189514 16943429 24234451 25348397 25416956 27705803 association,physical association two hybrid,experimental interaction detection,pull down,physical interaction,mammalian protein protein interaction trap,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,in vivo,tandem affinity purification,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
RYBP YY1 10369680 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RYBP E2F2 12411495 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
RYBP CASP10 11395500 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
RYBP CASP8 11395500 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
RYBP FADD 11395500 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RYBP RNF2 10369680 14525934 16943429 17070805 20696397 24234451 25348397 26496610 27705803 association,physical association anti tag coimmunoprecipitation,cosedimentation in solution,experimental interaction detection,nuclear magnetic resonance,pull down,surface plasmon resonance,x-ray crystallography,physical interaction,ion exchange chromatography,two hybrid array,in vivo,tandem affinity purification,surface plasmon resonance array,two hybrid prey pooling approach ComPPI,HPRD,IntAct
RYBP CBX2 10369680 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RYBP E2F3 12411495 14525934 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
RYBP E2F4 25348397 N/A physical interaction ComPPI
RYBP ABL1 25348397 N/A physical interaction ComPPI
RYBP MDM2 19098711 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct
RYBP TP53 19098711 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RYBP BCOR 24234451 25348397 27505670 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
RYBP PCGF1 16943429 24234451 25348397 27505670 27705803 association pull down,physical interaction,tandem affinity purification ComPPI,IntAct
RYBP SOCS2 25348397 N/A physical interaction ComPPI
RYBP ZFP42 25348397 N/A physical interaction ComPPI
RYBP ELAVL1 25348397 N/A physical interaction ComPPI
RYBP PCGF2 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
RYBP PCGF3 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
RYBP PCGF5 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
RYBP PCGF6 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
RYBP L3MBTL2 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
RYBP CBX3 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
RYBP TFDP1 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
RYBP MGA 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
RYBP BCORL1 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
RYBP KDM2B 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
RYBP USP7 25348397 N/A physical interaction ComPPI
RYBP FBRS 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
RYBP FBRSL1 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
RYBP CSNK2A1 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
RYBP CSNK2A2 23455922 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
RYBP CSNK2B 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
RYBP GABPB2 25348397 N/A physical interaction ComPPI
RYBP EED 25348397 N/A physical interaction ComPPI
RYBP MORC4 25348397 N/A physical interaction ComPPI
RYBP ATF7IP 25348397 N/A physical interaction ComPPI
RYBP HERC2 25348397 N/A physical interaction ComPPI
RYBP HERC2P3 25348397 N/A physical interaction ComPPI
RYBP AUTS2 24234451 25348397 25519132 27705803 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
RYBP HSPB1 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
RYBP CRK 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RYBP NOS1AP 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RYBP MAPK8IP2 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RYBP FANK1 25348397 N/A physical interaction ComPPI
RYBP DDX5 25348397 N/A physical interaction ComPPI
RYBP MLLT1 25348397 N/A physical interaction ComPPI
RYBP YAF2 25348397 N/A physical interaction ComPPI
RYBP TFDP2 25348397 N/A physical interaction ComPPI
RYBP HDAC1 25348397 N/A physical interaction ComPPI
RYBP DCAF7 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
RYBP TRIM25 25348397 N/A physical interaction ComPPI
RYBP MXD1 25348397 N/A physical interaction ComPPI
RYBP MAX 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
RYBP UBC 17070805 24234451 25348397 physical association anti tag coimmunoprecipitation,isothermal titration calorimetry,pull down ComPPI,IntAct
RYBP H2AC11 17070805 24234451 25348397 colocalization,physical association pull down,imaging technique ComPPI,IntAct
RYBP CBX1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
RYBP XAGE1A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PSMB1 RYBP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
WDR5 RYBP 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
RYBP ABL1 27898060 8943360 inhibition,stimulant N/A OmniPath

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