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GENE：UBE2V2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UBE2V2
FullNmae ubiquitin conjugating enzyme E2 V2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12495
EnsembleID ENSG00000169139
Uniprot Q15819

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UBE2V2 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
UBE2V2 GO:0000209,GO:0000729,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0006282,GO:0006301,GO:0016567,GO:0031372,GO:0031372,GO:0042275,GO:0070062,GO:0070534,GO:1902523,GO:2000781

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
UBE2V2 hsa:7336 path:hsa05131 Shigellosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
UBE2V2 BCL10 14695475 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
MALT1 UBE2V2 14695475 23180781 ubiquitination reaction enzymatic study InnateDB
UBE2V2 TRIM23 20724660 23180781 ubiquitination reaction enzymatic study InnateDB
UBE2V2 UBA1 20724660 23180781 ubiquitination reaction enzymatic study InnateDB
UBE2V2 UBE2N 16122702 23180781 24145445 physical association anti tag coimmunoprecipitation InnateDB
UBE2N UBE2V2 23180781 26101372 ubiquitination reaction ubiquitinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
AR UBE2V2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 UBE2V2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 UBE2V2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 UBE2V2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA UBE2V2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UBE2V2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 UBE2V2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 UBE2V2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 UBE2V2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 UBE2V2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A UBE2V2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF UBE2V2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 UBE2V2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 UBE2V2 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 UBE2V2 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 UBE2V2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000000B1C9 UBE2V2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000061E50F UBE2V2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000519450 UBE2V2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA UBE2V2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F UBE2V2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 UBE2V2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 UBE2V2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 UBE2V2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 UBE2V2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 UBE2V2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C UBE2V2 20371350 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000610EFA UBE2V2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000039D790 UBE2V2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000C7662 UBE2V2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000034979B UBE2V2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000EC1BE UBE2V2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001481F9 UBE2V2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDAA UBE2V2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000086A4D UBE2V2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000048D44E UBE2V2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000122F23 UBE2V2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 UBE2V2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075B538 UBE2V2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB14 UBE2V2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A UBE2V2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000007FBA UBE2V2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 UBE2V2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 UBE2V2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 UBE2V2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 UBE2V2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 UBE2V2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 UBE2V2 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TRAF6 UBE2V2 25361965 interaction type N/A PTMCode2
UBE2V2 TRAF6 25361965 interaction type N/A PTMCode2
STUB1 UBE2V2 25361965 interaction type N/A PTMCode2
UBE2V2 STUB1 25361965 interaction type N/A PTMCode2
UBE2N UBE2V2 25361965 interaction type N/A PTMCode2
UBE2V2 UBE2N 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
EIF1B UBE2V2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ZNRD2 UBE2V2 25348397 N/A physical interaction ComPPI
CD2BP2 UBE2V2 25348397 N/A physical interaction ComPPI
TRAF6 UBE2V2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
XIAP UBE2V2 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM32 UBE2V2 25348397 N/A physical interaction ComPPI
MKRN3 UBE2V2 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ZYX UBE2V2 25348397 N/A physical interaction ComPPI
UBE2L3 UBE2V2 25348397 N/A physical interaction ComPPI
RHOA UBE2V2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SIAH1 UBE2V2 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBC UBE2V2 11504715 12569095 12834344 16518696 25348397 27898060 N/A physical interaction ComPPI,OmniPath
UBE2N UBE2V2 11473244 11473255 14525934 18316726 19549727 24234451 25348397 27173435 association,physical association two hybrid,experimental interaction detection,x-ray crystallography,physical interaction,in vitro,tandem affinity purification,inference by socio-affinity scoring,two hybrid ComPPI,HPRD,IntAct
CANX UBE2V2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
UBE2B UBE2V2 25348397 N/A physical interaction ComPPI
TRAF2 UBE2V2 25348397 N/A physical interaction ComPPI
RNF8 UBE2V2 25348397 N/A physical interaction ComPPI
ZRANB2 UBE2V2 25348397 N/A physical interaction ComPPI
CPLX1 UBE2V2 25348397 N/A physical interaction ComPPI
EGFR UBE2V2 20029029 24234451 25348397 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
RNF2 UBE2V2 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SNTA1 UBE2V2 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
RAD23B UBE2V2 25348397 N/A physical interaction ComPPI
LRIF1 UBE2V2 14525934 16169070 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
BCL10 UBE2V2 14525934 14695475 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RIF1 UBE2V2 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
STUB1 UBE2V2 25348397 N/A physical interaction ComPPI
RNF11 UBE2V2 25348397 N/A physical interaction ComPPI
UBE2V1 UBE2V2 25348397 N/A physical interaction ComPPI
MOB4 UBE2V2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
UBE2V2 IGSF21 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
UBE2V2 SUV39H2 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
UBE2V2 HLTF 18316726 24234451 25348397 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
UBE2V2 ZNRF1 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2V2 DZIP3 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2V2 RNF144A 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2V2 TRIM5 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2V2 SHPRH 25348397 N/A pull down,physical interaction,physical interaction ComPPI
UBE2V2 OTUB1 25348397 N/A physical interaction ComPPI
UBE2V2 UBXN1 25348397 N/A physical interaction ComPPI
UBE2V2 USP9X 25348397 N/A physical interaction ComPPI
UBE2V2 USP34 25348397 N/A physical interaction ComPPI
UBE2V2 UBXN7 25348397 N/A physical interaction ComPPI
UBE2V2 TTLL12 25348397 N/A physical interaction ComPPI
UBE2V2 VPS26A 25348397 N/A physical interaction ComPPI
UBE2V2 SEC23A 25348397 N/A physical interaction ComPPI
UBE2V2 ZFYVE19 25348397 N/A physical interaction ComPPI
UBE2V2 ZPR1 25348397 N/A physical interaction ComPPI
UBE2V2 UFM1 25348397 N/A physical interaction ComPPI
UBE2V2 RPS21 25348397 N/A physical interaction ComPPI
UBE2V2 TTC9C 25348397 N/A physical interaction ComPPI
UBE2V2 MALT1 25348397 N/A physical interaction ComPPI
UBE2V2 UBE2M 25348397 N/A physical interaction ComPPI
UBE2V2 POLK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBE2V2 TIGD6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBE2V2 RC3H2 25348397 N/A physical interaction ComPPI
UBE2V2 RC3H1 25348397 N/A physical interaction ComPPI
UBE2V2 TP53 25348397 N/A physical interaction ComPPI
UBE2V2 USP14 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
MUL1 UBE2V2 25348397 N/A physical interaction ComPPI
MALSU1 UBE2V2 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
ATP6V1B2 UBE2V2 25348397 N/A physical interaction ComPPI
RBCK1 UBE2V2 24234451 30561431 association virotrap IntAct
TRADD UBE2V2 24234451 30561431 association virotrap IntAct
BIRC2 UBE2V2 24234451 30561431 association virotrap IntAct
SHPRH UBE2V2 17108083 27898060 stimulant N/A OmniPath

Visualization










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