Gene Information gene info

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GENE：DUT

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DUT
FullNmae deoxyuridine triphosphatase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3078
EnsembleID ENSG00000128951
Uniprot P33316

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DUT immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DUT autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DUT GO:0000287,GO:0001889,GO:0003723,GO:0004170,GO:0004170,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005739,GO:0006139,GO:0006226,GO:0006226,GO:0006231,GO:0006260,GO:0014070,GO:0030547,GO:0032556,GO:0042802,GO:0042975,GO:0043254,GO:0046081,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DUT hsa:1854 path:hsa00240 Pyrimidine metabolism - Homo sapiens (human)
DUT hsa:1854 path:hsa00983 Drug metabolism - other enzymes - Homo sapiens (human)
DUT hsa:1854 path:hsa01100 Metabolic pathways - Homo sapiens (human)
DUT hsa:1854 path:hsa01232 Nucleotide metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
DUT RHOB 19637314 23180781 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 DUT 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 DUT 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 DUT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DUT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DUT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DUT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 DUT N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 DUT 21512034 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000ED600 DUT 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EED18 DUT 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000003ABC4 DUT 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00002971AB DUT 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EC1BE DUT 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000006FDD4 DUT 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK1 DUT 22135298 phosphorylation N/A PhosphoSite
DUT DUT 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SPATA2 DUT 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PLEKHF2 DUT 19060904 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach ComPPI,IntAct
HSPA8 DUT 25348397 N/A physical interaction ComPPI
CDC42 DUT 25348397 N/A physical interaction ComPPI
CFL1 DUT 25348397 N/A physical interaction ComPPI
UBL4A DUT 25348397 N/A physical interaction ComPPI
GABARAPL2 DUT 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
COTL1 DUT 25348397 N/A physical interaction ComPPI
MCM2 DUT 25348397 N/A physical interaction ComPPI
GDI2 DUT 25348397 N/A physical interaction ComPPI
GRB2 DUT 12577067 24234451 25348397 association pull down ComPPI,IntAct
CTBP1 DUT 25348397 N/A physical interaction ComPPI
RHOB DUT 19637314 24234451 25348397 physical association two hybrid ComPPI,IntAct
ARHGDIA DUT 25348397 N/A physical interaction ComPPI
CUL3 DUT 25348397 N/A physical interaction ComPPI
PPARA DUT 25348397 N/A two hybrid,in vitro,in vivo ComPPI
DUT NUDT18 14525934 16189514 19060904 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
DUT PPARD 14525934 25348397 8910358 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
DUT ESR1 14525934 15604093 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
DUT ESRRA 14525934 15604093 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
DUT ESRRG 14525934 15604093 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
DUT LEMD3 25348397 N/A physical interaction ComPPI
DUT RPL38 25348397 N/A physical interaction ComPPI
DUT MRPL14 25348397 N/A physical interaction ComPPI
DUT C19ORF25 25348397 N/A physical interaction ComPPI
DUT ABCE1 25348397 N/A physical interaction ComPPI
DUT AK2 25348397 N/A physical interaction ComPPI
DUT ALDOA 25348397 N/A physical interaction ComPPI
DUT CKS2 25348397 N/A physical interaction ComPPI
DUT CTH 25348397 N/A physical interaction ComPPI
DUT DAZAP1 25348397 N/A physical interaction ComPPI
DUT ELAVL1 25348397 N/A physical interaction ComPPI
DUT ENO1 25348397 N/A physical interaction ComPPI
DUT ENO2 25348397 N/A physical interaction ComPPI
DUT ENO3 25348397 N/A physical interaction ComPPI
DUT FKBP5 25348397 N/A physical interaction ComPPI
DUT FKBP7 25348397 N/A physical interaction ComPPI
DUT FUBP1 25348397 N/A physical interaction ComPPI
DUT G6PD 25348397 N/A physical interaction ComPPI
DUT GAPDH 25348397 N/A physical interaction ComPPI
DUT GPX4 25348397 N/A physical interaction ComPPI
DUT GRPEL1 25348397 N/A physical interaction ComPPI
DUT GSTO1 25348397 N/A physical interaction ComPPI
DUT HINT1 25348397 N/A physical interaction ComPPI
DUT HSPB1 25348397 N/A physical interaction ComPPI
DUT IMPA1 25348397 N/A physical interaction ComPPI
DUT IMPA2 25348397 N/A physical interaction ComPPI
DUT NUDT9 25348397 N/A physical interaction ComPPI
DUT PLIN3 25348397 N/A physical interaction ComPPI
DUT PPA1 25348397 N/A physical interaction ComPPI
DUT PPA2 25348397 N/A physical interaction ComPPI
DUT PPP1R11 25348397 N/A physical interaction ComPPI
DUT PPP5C 25348397 N/A physical interaction ComPPI
DUT PRDX2 25348397 N/A physical interaction ComPPI
DUT PRDX5 25348397 N/A physical interaction ComPPI
DUT RAB11B 25348397 N/A physical interaction ComPPI
DUT SELENBP1 25348397 N/A physical interaction ComPPI
DUT SPR 25348397 N/A physical interaction ComPPI
DUT STIP1 25348397 N/A physical interaction ComPPI
DUT STMN1 25348397 N/A physical interaction ComPPI
DUT TAGLN2 25348397 N/A physical interaction ComPPI
DUT TAGLN3 25348397 N/A physical interaction ComPPI
DUT TKT 25348397 N/A physical interaction ComPPI
DUT TPD52 25348397 N/A physical interaction ComPPI
DUT TRAP1 25348397 N/A physical interaction ComPPI
DUT UMPS 25348397 N/A physical interaction ComPPI
DUT EEF1A1 25348397 N/A physical interaction ComPPI
DUT EEF1A1P5 25348397 N/A physical interaction ComPPI
DUT HNRNPA1 25348397 N/A physical interaction ComPPI
DUT HSPA4L 25348397 N/A physical interaction ComPPI
DUT MSN 25348397 N/A physical interaction ComPPI
DUT RAB1A 25348397 N/A physical interaction ComPPI
DUT RAB1C 25348397 N/A physical interaction ComPPI
DUT RAB1B 25348397 N/A physical interaction ComPPI
DUT TIAL1 25348397 N/A physical interaction ComPPI
DUT TYMS 25348397 N/A physical interaction ComPPI
DUT DUSP13 25348397 N/A physical interaction ComPPI
DUT DUSP13 25348397 N/A physical interaction ComPPI
DUT PINX1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DUT GH1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DUT GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DUT GABARAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DUT KDM4A 23871696 24234451 25348397 association pull down ComPPI,IntAct
DUT CDK8 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
DUT HSPD1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
DUT PDK1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HSPA9 DUT 25348397 N/A physical interaction ComPPI
ALDOC DUT 25348397 N/A physical interaction ComPPI
MGST3 DUT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CDK1 DUT 14525934 8631817 N/A experimental interaction detection HPRD
DUT DUT 14525934 8805593 N/A experimental interaction detection HPRD
SMARCB1 DUT 24234451 30108113 association proximity-dependent biotin identification IntAct
CDK1 DUT 12799180 18212344 19415658 19651622 19664995 20068231 24311590 27898060 8631817 N/A N/A OmniPath
CSNK2A1 DUT 27898060 8389461 N/A N/A OmniPath

Visualization










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