GENE:SHTN1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | SHTN1 |
| FullNmae | shootin 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:29319 |
| EnsembleID | ENSG00000187164 |
| Uniprot | A0MZ66 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| SHTN1 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| SHTN1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| SHTN1 | GO:0005515,GO:0005737,GO:0005737,GO:0005874,GO:0005875,GO:0006930,GO:0007265,GO:0007409,GO:0015630,GO:0019894,GO:0030027,GO:0030175,GO:0030424,GO:0030426,GO:0031252,GO:0031252,GO:0032488,GO:0038007,GO:0043204,GO:0044295,GO:0044295,GO:0045296,GO:0045773,GO:0048471,GO:0048812,GO:0048812,GO:0051015,GO:0060327,GO:0061163,GO:0061573,GO:2000114,GO:2001224,GO:2001224 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | SHTN1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | SHTN1 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA3 | SHTN1 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | SHTN1 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| CEBPA | SHTN1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | SHTN1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | SHTN1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | SHTN1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | SHTN1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | SHTN1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | SHTN1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | SHTN1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | SHTN1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | SHTN1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| FABP3 | SHTN1 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| YWHAG | SHTN1 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| KEAP1 | SHTN1 | 25348397 | N/A | physical interaction | ComPPI |
| FAM167A | SHTN1 | 25348397 | N/A | physical interaction | ComPPI |
| NTRK1 | SHTN1 | 25348397 | N/A | physical interaction | ComPPI |
| CDH1 | SHTN1 | 25348397 | N/A | physical interaction | ComPPI |
| HSP90B1 | SHTN1 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPL | SHTN1 | 25348397 | N/A | physical interaction | ComPPI |
| BCHE | SHTN1 | 25348397 | N/A | physical interaction | ComPPI |
| UBA2 | SHTN1 | 25348397 | N/A | physical interaction | ComPPI |
| CAV3 | SHTN1 | 25348397 | N/A | physical interaction | ComPPI |
| TFCP2 | SHTN1 | 25348397 | N/A | physical interaction | ComPPI |
| SIRT1 | SHTN1 | 25348397 | N/A | physical interaction | ComPPI |
| NEDD4 | SHTN1 | 25348397 | N/A | physical interaction | ComPPI |
| MEGF10 | SHTN1 | 12421765 14525934 24234451 25348397 | physical association | two hybrid,two hybrid | ComPPI,HPRD,IntAct |
| NDEL1 | SHTN1 | 25348397 | N/A | physical interaction | ComPPI |
| CAP1 | SHTN1 | 25348397 | N/A | physical interaction | ComPPI |
| ESRRG | SHTN1 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| TPM4 | SHTN1 | 25348397 | N/A | physical interaction | ComPPI |
| ZCCHC17 | SHTN1 | 25348397 | N/A | physical interaction | ComPPI |
| LNX1 | SHTN1 | 25348397 | N/A | physical interaction | ComPPI |
| VPS29 | SHTN1 | 25348397 | N/A | physical interaction | ComPPI |
| SHTN1 | IKBKG | 20098747 24234451 25348397 | N/A | protein array,physical interaction | ComPPI,IntAct |
| SHTN1 | AHCYL1 | 25348397 | N/A | physical interaction | ComPPI |
| SHTN1 | UBXN1 | 25348397 | N/A | physical interaction | ComPPI |
| SHTN1 | SEC24A | 25348397 | N/A | physical interaction | ComPPI |
| SHTN1 | UNK | 25348397 | N/A | physical interaction | ComPPI |
| SHTN1 | PSAT1 | 25348397 | N/A | physical interaction | ComPPI |
| SHTN1 | KCTD12 | 25348397 | N/A | physical interaction | ComPPI |
| SHTN1 | OGFR | 25348397 | N/A | physical interaction | ComPPI |
| SHTN1 | TPM1 | 25348397 | N/A | physical interaction | ComPPI |
| SHTN1 | TRMT6 | 25348397 | N/A | physical interaction | ComPPI |
| SHTN1 | NME7 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| SHTN1 | LURAP1L | 25348397 | N/A | physical interaction | ComPPI |
| SHTN1 | MED4 | 25348397 | N/A | physical interaction | ComPPI |
| FASN | SHTN1 | 25348397 | N/A | physical interaction | ComPPI |
| BBOX1 | SHTN1 | 25348397 | N/A | physical interaction | ComPPI |
| SHTN1 | SHTN1 | 24234451 25416956 | physical association | two hybrid array | IntAct |
| ARL6IP5 | SHTN1 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| PRAF2 | SHTN1 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| IKBKG | SHTN1 | 20098747 27898060 | N/A | N/A | OmniPath |
